Article
Biophysics
Masoud Eskandani, Morteza Eskandani, Somayeh Vandghanooni, Bahman Navidshad, Farzad Mirzaei Aghjehgheshlagh, Ali Nobakht
Summary: This study successfully enhanced the bioavailability of L-carnitine (LC) using solid lipid nanoparticles (SLNs) as carriers and demonstrated the protective effects of LC-SLNs against intracellular oxidative stress damages.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Environmental Sciences
Chantale Andre, Samuel Turgeon, Caroline Peyrot, Kevin James Wilkinson, Joelle Auclair, Nadia Menard, Francois Gagne
Summary: This study examines the toxicity of different sizes of poly-styrene nanoparticles (PsNP) to marine clams. The results show that PsNP of smaller sizes accumulate more in the digestive gland and have higher oxidative stress and tissue damage. Moreover, the 100 nm PsNP also alters levels of the circadian metabolite melatonin.
MARINE POLLUTION BULLETIN
(2023)
Article
Environmental Sciences
Iteb Boughattas, Nesrine Zitouni, Marouane Mkhinini, Omayma Missawi, Sondes Helaoui, Sabrine Hattab, Moncef Mokni, Noureddine Bousserrhine, Mohamed Banni
Summary: This study investigated the effects of biochar on earthworms in soil remediation. The results showed that in the presence of biochar, the bioavailability of Cd and 2,4-D increased in earthworms, along with an increase in micronuclei frequency and a decrease in lysosomal membrane stability. Histopathological examination revealed numerous alterations in animals exposed to contaminants without any amelioration when biochar was added. The biochemical response of earthworms demonstrated that in the presence of biochar, animals tended to alleviate the toxicity of Cd and 2,4-D.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Maria Rachele Guascito, Maria Giulia Lionetto, Franco Mazzotta, Marianna Conte, Maria Elena Giordano, Roberto Caricato, Anna Rita De Bartolomeo, Adelaide Dinoi, Daniela Cesari, Eva Merico, Laura Mazzotta, Daniele Contini
Summary: In this study, the toxicity of atmospheric particulate matter (PM) was investigated through in vitro experiments. The results showed correlations between extracellular and intracellular toxicity indicators, and significant effects of combustion sources on these toxicity indicators. Additionally, the advection of African dust resulted in lower intrinsic toxicity indicators.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Sabrine Hattab, Iteb Boughattas, Tiziana Cappello, Nesrine Zitouni, Ghada Touil, Ilef Romdhani, Alexandre Livet, Nourreddine Bousserrhine, Mohamed Banni
Summary: Heavy metal pollution has harmful consequences on soil fertility, and earthworms are used as test organisms to evaluate the ecotoxicity of polluted soils. This study exposed Eisenia andrei to polymetallic contaminated soils for 7 and 14 days in southeastern Tunisia. The results showed increased heavy metal accumulation, genotoxicity, and cytotoxicity in earthworms after 14 days of exposure, as well as changes in biochemical and transcriptional responses. These findings support the use of earthworms as bioindicator species for pollution monitoring and provide valuable information about the harmful impact of biota exposure to contaminated soils.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Marine
Nadezda Vladimirovna Dovzhenko, Victor Pavlovich Chelomin, Andrey Alexandrovich Mazur, Sergey Petrovich Kukla, Valentina Vladimirovna Slobodskova, Aleksandra Anatolievna Istomina, Avianna Fayazovna Zhukovskaya
Summary: The ingress of nanoparticles of metal oxides and microfragments of synthetic polymers into a marine environment causes unpredictable consequences. However, the effects of these particles are difficult to predict due to a lack of ecotoxicological information. In a laboratory experiment on Mytilus trossulus, it was found that both CuO-NPs and mu PSs induced oxidative stress and had varying degrees of impact on the mollusks.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Una Stamenovic, Sladana Davidovic, Sandra Petrovic, Andreja Leskovac, Milovan Stoiljkovic, Vesna Vodnik
Summary: Two Ag-PANI/PVP nanocomposites with similar silver content but different morphologies were prepared by integrating silver nanoparticles during oxidative polymerization. These nanocomposites showed strong antimicrobial potential against indicator microbial strains, making them suitable for non-medical applications like wastewater treatment.
NEW JOURNAL OF CHEMISTRY
(2021)
Review
Environmental Sciences
Ingra Tais Malacarne, Daniel Vitor De Souza, Barbara Dos Anjos Rosario, Milena De Barros Viana, Camilo Dias Seabra Pereira, Debora Estadella, Jean Nunes dos Santos, Daniel Araki Ribeiro
Summary: Crack-cocaine can induce genotoxicity and oxidative stress in mammalian cells, and studies have shown evidence supporting its role as a chemical carcinogen. However, the impact of inflammatory response after exposure to crack-cocaine remains inconclusive.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Toxicology
Nancy B. Andrioli, Gabriela Chaufan
Summary: The study evaluated the genotoxicity and oxidative stress in the A549 cell line exposed to sublethal concentrations of Iprodione. The increase in Iprodione concentrations slightly raised the probability of belonging to the genotoxic category, while oxidative stress analysis showed a significant linear increase in SOD and a significant linear decrease in GSH and GST.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Narayanam Phani Satyanarayana Acharyulu, Arya Sohan, Pravallika Banoth, Srinivasu Chintalapati, Sejal Doshi, Venu Reddy, Chella Santhosh, Andrews Nirmala Grace, Luis De Los Santos Valladares, Pratap Kollu
Summary: This study prepared nickel ferrite nanoparticles and nickel/nickel ferrite graphene oxide nanocomposites and evaluated their toxic effects on E. coli cells. The results showed that the nanocomposites induced cell death in E. coli through reactive oxygen species (ROS) generation and oxidative stress.
Article
Pharmacology & Pharmacy
Pamela Soledad Bustos, Melisa de los Angeles Quinteros, Diego Sebastian Gomez, Maria Gabriela Ortega, Paulina Laura Paez, Natalia Lorena Guinazu
Summary: This study investigated the effects of silver bionanoparticles (AgNPs) on human trophoblasts, revealing changes in cell morphology, reduced cell viability, alterations in redox balance with increased ROS and RNS levels, as well as protein oxidation and genotoxic damage. The cytotoxicity of AgNPs was found to be mediated by nitric oxide and glutathione pathways, highlighting differences in toxicity mechanisms between eukaryotic and prokaryotic cells and emphasizing the importance of toxicity evaluation for the safety of AgNPs with pharmaceutical applications.
Review
Biochemistry & Molecular Biology
Monika Sharma, Nikhil Maheshwari, Fahim Halim Khan, Riaz Mahmood
Summary: The extensive use of harmful pesticides in agriculture, including Carbendazim (CBZ), poses serious threats to the environment and human health. CBZ has been found to cause various health problems, including endocrine disruption, embryo toxicity, and neurodegenerative disorders.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Wenfeng Zhu, Yake Liu, Wei Wang, Zihua Zhou, Jin-hua Gu, Zexu Zhang, Huanjian Sun, Fan Liu
Summary: The study revealed that CoNPs exert toxicity on human vascular endothelial cells by depleting intracellular Fe2+ level, leading to activation of HIF-1 alpha. Supplementation of Fe2+, especially in the form of Fe(CH3CHOHCOO)(2) and Fe(CH2COO)(2), mitigates CoNP toxicity.
BIOSCIENCE REPORTS
(2021)
Article
Engineering, Environmental
Mislav Mustapic, Zvonko Glumac, Marija Heffer, Milorad Zjalic, Ivan Proloscic, Mostafa Masud, Senka Blazetic, Ana Vukovic, Motasim Billah, Aslam Khan, Suzana Segota, Md Shahriar Al Hossain
Summary: The research developed a drug delivery system based on combined AC/DC magnetic fields, using a magnetic syringe device to stimulate drug release and reduce cell viability, with the removal of drug carriers to prevent potential side effects in the patient's body.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Engineering, Environmental
Ashiq Ahamed, Lili Liang, Ming Yang Lee, Johan Bobacka, Grzegorz Lisak
Summary: Engineered nanomaterials (ENMs) are a novel class of materials with superior physicochemical properties compared to conventional materials, but can potentially release into the environment and pose toxic effects. Research focuses on the transformations and potential risks of ENMs in consumer products, aiming to ensure their safe application.
JOURNAL OF HAZARDOUS MATERIALS
(2021)