Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida

Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy

(2017) Emily L. Que et al.   Integrative Biology

A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice

(2017) Bo Xiong et al.   PLoS Genetics

Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes

(2016) Ling Han et al.   CURRENT BIOLOGY

Down-regulation of the liver-derived plasma protein fetuin-B mediates reversible female infertility

(2016) J. Floehr et al.   MOLECULAR HUMAN REPRODUCTION

Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes

(2016) E. Dietzel et al.   MOLECULAR HUMAN REPRODUCTION

Structure of IZUMO1–JUNO reveals sperm–oocyte recognition during mammalian fertilization

(2016) Umeharu Ohto et al.   NATURE

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex

(2016) Halil Aydin et al.   NATURE

Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors

(2015) Eusebio S Pires et al.   Oncotarget

Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B

(2014) Walter Stöcker et al.   BIOLOGICAL CHEMISTRY

A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans

(2014) Matteo A. Avella et al.   JOURNAL OF CELL BIOLOGY

Juno is the egg Izumo receptor and is essential for mammalian fertilization

(2014) Enrica Bianchi et al.   NATURE

Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

(2014) Emily L. Que et al.   Nature Chemistry

Identification of Potential Oviductal Factors Responsible for Zona Pellucida Hardening and Monospermy During Fertilization in Mammals1

(2013) Irene Mondéjar et al.   BIOLOGY OF REPRODUCTION

Fetuin-B, a Liver-Derived Plasma Protein Is Essential for Fertilization

(2013) Eileen Dietzel et al.   DEVELOPMENTAL CELL

SAS1B protein [ovastacin] shows temporal and spatial restriction to oocytes in several eutherian orders and initiates translation at the primary to secondary follicle transition

(2013) Eusebio S. Pires et al.   DEVELOPMENTAL DYNAMICS

Functional and structural insights into astacin metallopeptidases

(2012) F. Xavier Gomis-Rüth et al.   BIOLOGICAL CHEMISTRY

Oocytes use the plasminogen-plasmin system to remove supernumerary spermatozoa

(2012) Pilar Coy et al.   HUMAN REPRODUCTION

Secretome profile of mouse oocytes after activation using mass spectrum

(2012) Qiuping Peng et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy

(2012) Anna D. Burkart et al.   JOURNAL OF CELL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Structural basis for the sheddase function of human meprin   metalloproteinase at the plasma membrane

(2012) J. L. Arolas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization

(2011) Monika Sachdev et al.   DEVELOPMENTAL BIOLOGY

Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates

(2011) Christoph Becker-Pauly et al.   MOLECULAR & CELLULAR PROTEOMICS

Proenzyme Structure and Activation of Astacin Metallopeptidase

(2010) Tibisay Guevara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gamete Recognition in Mice Depends on the Cleavage Status of an Egg's Zona Pellucida Protein

(2010) G. Gahlay et al.   SCIENCE