Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery

标题
Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery
作者
关键词
protein tyrosine phosphatase, PTP1B, enzyme, NMR spectroscopy, X-ray crystallography, allostery, protein dynamics, fast and intermediate timescale dynamics
出版物
MOLECULAR CELL
Volume 65, Issue 4, Pages 644-658.e5
出版商
Elsevier BV
发表日期
2017-02-17
DOI
10.1016/j.molcel.2017.01.014

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