Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species

The potential role of Akt phosphorylation in human cancers

(2017) J. Cicenas   INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS

Creatine supplementation with methylglyoxal: a potent therapy for cancer in experimental models

(2016) Aparajita Pal et al.   AMINO ACIDS

Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells

(2016) Mahua R. Das et al.   BMC CANCER

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

ROS and energy metabolism in cancer cells: alliance for fast growth

(2015) Sang Won Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2

(2015) Yi Guo et al.   CANCER BIOLOGY & THERAPY

High Expression of Pyruvate Kinase M2 is Associated with Chemosensitivity to Epirubicin and 5-Fluorouracil in Breast Cancer

(2015) Yang Lin et al.   Journal of Cancer

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma

(2015) Shanmugasundaram Ganapathy-Kanniappan et al.   Oncotarget

Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes

(2015) Barbara Chiavarina et al.   Oncotarget

Immunomodulation of macrophages by methylglyoxal conjugated with chitosan nanoparticles against Sarcoma-180 tumor in mice

(2013) Adrita Chakrabarti et al.   CELLULAR IMMUNOLOGY

A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells

(2013) Cinzia Antognelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Advanced glycation end-products induce injury to pancreatic beta cells through oxidative stress

(2012) N. Lin et al.   DIABETES & METABOLISM

Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells bothin vitroandin vivo

(2012) Junghyun Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Methylglyoxal induces mitochondria-dependent apoptosis in sarcoma

(2011) A. Ghosh et al.   BIOCHEMISTRY-MOSCOW

Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocysts

(2011) Fu-Jen Huang et al.   ENVIRONMENTAL TOXICOLOGY

Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose

(2011) Ki Mo Kim et al.   EXPERIMENTAL CELL RESEARCH

Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin

(2010) Zhi-Jun Sun et al.   APOPTOSIS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Triple-negative breast cancer: Present challenges and new perspectives

(2010) Franca Podo et al.   Molecular Oncology

Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells

(2009) Junghyun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Critical evaluation of toxic versus beneficial effects of methylglyoxal

(2009) D. Talukdar et al.   BIOCHEMISTRY-MOSCOW

A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells

(2008) Hyun Kyoung Lee et al.   JOURNAL OF NEUROCHEMISTRY