C-terminus of the P4-ATPase ATP8A2 functions in protein folding and regulation of phospholipid flippase activity

P4-ATPases as Phospholipid Flippases—Structure, Function, and Enigmas

(2016) Jens P. Andersen et al.   Frontiers in Physiology

Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

(2015) S. Lee et al.   EMBO JOURNAL

Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival

(2014) J. A. Coleman et al.   JOURNAL OF CELL SCIENCE

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2

(2014) A. L. Vestergaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

(2014) K. Segawa et al.   SCIENCE

C-Terminal Truncations of the Saccharomyces cerevisiae PMA1 H + -ATPase Have Major Impacts on Protein Conformation, Trafficking, Quality Control, and Function

(2013) A. Brett Mason et al.   EUKARYOTIC CELL

Differential Phospholipid Substrates and Directional Transport by ATP-binding Cassette Proteins ABCA1, ABCA7, and ABCA4 and Disease-causing Mutants

(2013) Faraz Quazi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Auto-inhibition of Drs2p, a Yeast Phospholipid Flippase, by Its Carboxyl-terminal Tail

(2013) Xiaoming Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P4-ATPases: lipid flippases in cell membranes

(2013) Rosa L. Lopez-Marques et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

(2013) Mattia Malvezzi et al.   Nature Communications

Phospholipid flippases: Building asymmetric membranes and transport vesicles

(2012) Tessy T. Sebastian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport

(2012) Jonathan A. Coleman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Missense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar atrophy and quadrupedal locomotion

(2012) Onur Emre Onat et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

P4-ATPase ATP8A2 acts in synergy with CDC50A to enhance neurite outgrowth

(2012) Qin Xu et al.   FEBS LETTERS

Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2

(2012) J. A. Coleman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases

(2012) R. D. Baldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in a P-Type ATPase Gene Cause Axonal Degeneration

(2012) Xianjun Zhu et al.   PLoS Genetics

Critical Role of the β-Subunit CDC50A in the Stable Expression, Assembly, Subcellular Localization, and Lipid Transport Activity of the P4-ATPase ATP8A2

(2011) Jonathan A. Coleman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions of phospholipid flippases

(2010) K. Tanaka et al.   JOURNAL OF BIOCHEMISTRY

Heteromeric Interactions Required for Abundance and Subcellular Localization of Human CDC50 Proteins and Class 1 P4-ATPases

(2010) Lieke M. van der Velden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump

(2010) Jesper V. Møller et al.   QUARTERLY REVIEWS OF BIOPHYSICS

P4 ATPases - Lipid flippases and their role in disease

(2009) Dineke E. Folmer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Localization, Purification, and Functional Reconstitution of the P4-ATPase Atp8a2, a Phosphatidylserine Flippase in Photoreceptor Disc Membranes

(2009) Jonathan A. Coleman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

(2009) Takehiro Shinoda et al.   NATURE

Regulation of a Golgi flippase by phosphoinositides and an ArfGEF

(2009) Paramasivam Natarajan et al.   NATURE CELL BIOLOGY