Nucleosome–nucleosome interactions via histone tails and linker DNA regulate nuclear rigidity

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleosomal arrays self‐assemble into supramolecular globular structures lacking 30‐nm fibers

(2016) Kazuhiro Maeshima et al.   EMBO JOURNAL

CTCF: making the right connections

(2016) Rodolfo Ghirlando et al.   GENES & DEVELOPMENT

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo

(2016) Chen Chen et al.   MOLECULAR BIOLOGY OF THE CELL

SMC complexes: from DNA to chromosomes

(2016) Frank Uhlmann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nongenetic functions of the genome

(2016) M. Bustin et al.   SCIENCE

Uncovering the forces between nucleosomes using DNA origami

(2016) J. J. Funke et al.   Science Advances

Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C

(2015) Tsung-Han S. Hsieh et al.   CELL

Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo

(2015) Maria Aurelia Ricci et al.   CELL

Lamins: the structure and protein complexes

(2015) Yosef Gruenbaum et al.   CURRENT OPINION IN CELL BIOLOGY

Structural and functional diversity of Topologically Associating Domains

(2015) Job Dekker et al.   FEBS LETTERS

Lamins at the crossroads of mechanosignaling

(2015) Selma Osmanagic-Myers et al.   GENES & DEVELOPMENT

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

(2015) Adrian L. Sanborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

(2015) Takashi Furusawa et al.   Nature Communications

The tethering of chromatin to the nuclear envelope supports nuclear mechanics

(2015) Sarah M. Schreiner et al.   Nature Communications

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units

(2014) F. Song et al.   SCIENCE

Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes

(2013) Lu Gan et al.   CHROMOSOMA

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Genome organization and long-range regulation of gene expression by enhancers

(2013) Andrea Smallwood et al.   CURRENT OPINION IN CELL BIOLOGY

The role of the nucleosome acidic patch in modulating higher order chromatin structure

(2013) A. A. Kalashnikova et al.   Journal of the Royal Society Interface

Probing the compressibility of tumor cell nuclei by combined atomic force–confocal microscopy

(2013) Marina Krause et al.   PHYSICAL BIOLOGY

Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations

(2013) Ashwat Visvanathan et al.   PLoS One

Chromatin Compaction Protects Genomic DNA from Radiation Damage

(2013) Hideaki Takata et al.   PLoS One

Broken nuclei – lamins, nuclear mechanics, and disease

(2013) Patricia M. Davidson et al.   TRENDS IN CELL BIOLOGY

Revisiting higher-order and large-scale chromatin organization

(2012) Qian Bian et al.   CURRENT OPINION IN CELL BIOLOGY

Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure

(2012) Yoshinori Nishino et al.   EMBO JOURNAL

Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres

(2012) Eden Fussner et al.   EMBO REPORTS

Condensins: universal organizers of chromosomes with diverse functions

(2012) T. Hirano   GENES & DEVELOPMENT

Microneedle-based analysis of the micromechanics of the metaphase spindle assembled in Xenopus laevis egg extracts

(2012) Yuta Shimamoto et al.   Nature Protocols

Nuclear lamin functions and disease

(2012) Veronika Butin-Israeli et al.   TRENDS IN GENETICS

Chromosomes without a 30-nm chromatin fiber

(2012) Yasumasa Joti et al.   Nucleus

Nuclear Mechanics in Disease

(2011) Monika Zwerger et al.   Annual Review of Biomedical Engineering

Insights into the Micromechanical Properties of the Metaphase Spindle

(2011) Yuta Shimamoto et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Nuclear mechanics in differentiation and development

(2011) Bernhard Hampoelz et al.   CURRENT OPINION IN CELL BIOLOGY

Chromatin structure: does the 30-nm fibre exist in vivo?

(2010) Kazuhiro Maeshima et al.   CURRENT OPINION IN CELL BIOLOGY

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

(2010) A. Buxboim et al.   JOURNAL OF CELL SCIENCE

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

Revealing the high-resolution three-dimensional network of chromatin and interchromatin space: A novel electron-microscopic approach to reconstructing nuclear architecture

(2009) Jacques Rouquette et al.   CHROMOSOME RESEARCH

Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber

(2009) Maarten Kruithof et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamics of Chromatin Decondensation Reveals the Structural Integrity of a Mechanically Prestressed Nucleus

(2008) Aprotim Mazumder et al.   BIOPHYSICAL JOURNAL

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ

(2008) M. Eltsov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA