Article
Chemistry, Analytical
Caifen Chen, Dan Li, Baokang Jin
Summary: A selective and sensitive electrochemical biosensor is developed for detecting bisphenol A (BPA) by target-induced chain release. The biosensor utilizes a premodified gold electrode to immobilize capture DNA, and the binding of BPA to the aptamer leads to the release of the DNA chain, resulting in a reduction of the current signal.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Seowon Lee, Won Jae Kim, Minsub Chung
Summary: The importance of specific DNA detection is discussed in various fields, with a focus on label-free DNA sensing using techniques like electrochemical impedance spectroscopy and quartz crystal microbalance. The study reveals the etching effect of the ferro/ferricyanide redox couple on gold electrodes, and how experimental parameters and probe-DNA concentrations can be optimized for signal amplification in detecting complementary DNA.
Article
Materials Science, Multidisciplinary
Ambale Murthy Madhusudhana, Kikkeri Narasimha Shetty Mohana, Mahesh Bhaskar Hegde, Ningappa Kumara Swamy, Santhosh Arehalli Shivamurthy
Summary: An electrochemical sensor was developed for the detection of caffeine by drop-casting ZnO/GO-phenol formaldehyde amine (ZnO/GO-PFA) nanocomposite onto a graphite electrode. The sensor exhibited strong electrocatalytic behavior and a linear oxidation peak in the concentration range of 5-155 μM with a detection limit of 0.15 μM. The increased surface area of ZnO/GO led to improved stability and repeatability.
DIAMOND AND RELATED MATERIALS
(2022)
Article
Chemistry, Analytical
Ferdaous Maatouk, Mouna Maatouk, Barhoumi Houcine, Nicole Jaffrezic
Summary: A simple and inexpensive DNA biosensor based on a gold nanoparticle/glutathione matrix was developed for characterizing DNA hybridization, showing excellent sensitivity in detecting target DNA and interactions with drugs and micropollutants in wastewater. The biosensor had a linear response range from 7 pM to 5 nM and could efficiently measure interactions in the dynamic range of 1 pM to 10 mu M.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Yu Zheng, Lele Wang, Li Xu, Yan Li, Xue Yang, Zhenzhou Yang, Lanying Li, Min Ding, Shuzhen Ren, Feiyan Gong, Jinxue Chang, Chengming Cao, Yanli Wen, Liang Li, Gang Liu
Summary: RNA interference (RNAi) technology has great potential in agriculture. Researchers have developed a novel RNA electrochemical biosensor for analyzing RNA molecules in GM maize samples. The biosensor shows high sensitivity and specificity, providing a reliable measurement method for RNAi safety and quality assessment.
Article
Biology
Kevin S. Kuchinski, Kara D. Loos, Danae M. Suchan, Jennifer N. Russell, Ashton N. Sies, Charles Kumakamba, Francisca Muyembe, Placide Mbala Kingebeni, Ipos Ngay Lukusa, Frida N'Kawa, Joseph Atibu Losoma, Maria Makuwa, Amethyst Gillis, Matthew LeBreton, James A. Ayukekbong, Nicole A. Lerminiaux, Corina Monagin, Damien O. Joly, Karen Saylors, Nathan D. Wolfe, Edward M. Rubin, Jean J. Muyembe Tamfum, Natalie A. Prystajecky, David J. McIver, Christian E. Lange, Andrew D. S. Cameron
Summary: This study evaluated the feasibility of using hybridization probe capture technique to recover more extensive genomic information from specimens. The results showed that probe capture achieved more genome sequence compared to standard amplicon sequencing protocols, and identified new coronaviruses. The study suggests that probe capture can be effectively used alongside other sequencing technologies for high-throughput discovery and surveillance of coronaviruses.
Article
Engineering, Electrical & Electronic
Stefano Bonaldo, Lara Franchin, Elisabetta Pasqualotto, Erica Cretaio, Carmen Losasso, Arianna Peruzzo, Alessandro Paccagnella
Summary: The influence of bovine serum albumin (BSA) protein on the electrochemical response of a DNA-based biosensor is explored. The steric hindrance caused by BSA greatly affects the electrochemical signal and decreases the device sensitivity. A novel treatment method using proteinase K is proposed to improve the genosensor sensitivity.
IEEE SENSORS JOURNAL
(2023)
Article
Biophysics
Appan Roychoudhury, James W. Dear, Till T. Bachmann
Summary: This study presents a new strategy and level of mechanistic understanding for ultrasensitive detection of short, non-coding RNAs without target amplification or chemical modification using electrochemical biosensors. The optimized arrangements of the EIS biosensor system enabled the detection of microRNA-122, a known biomarker for liver injury.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Physical
Lei Wang, Kathleen Frisella, Pattarachai Srimuk, Oliver Janka, Guido Kickelbick, Volker Presser
Summary: The study found that the addition of Ca2+ and dissolved oxygen in the solution exacerbates the capacity fading of LiFePO4, while Na+ and Mg2+ have little influence on its stability. By continuously flushing nitrogen into the electrolyte and coating the electrode material with carbon, the stability of LiFePO4 was significantly enhanced, with the capacity retention of 82% in 10 cycles under certain conditions.
SUSTAINABLE ENERGY & FUELS
(2021)
Article
Chemistry, Analytical
Mei Zhao, Guangrong Zou, Jing Tang, Jingyi Guo, Fang Wang, Zilin Chen
Summary: 5-carboxycytosine (5caC) is a crucial intermediate form in DNA methylation and demethylation processes, and its distribution and quantity have significant effects on organism's normal physiological activities. Due to its low abundance, detecting 5caC presents a challenge. In response, we propose a selective method for 5caC detection using differential pulse voltammetry (DPV) at a glassy carbon electrode (GCE) with probe labeling. This method allows quantitative detection of 5caC with good linearity and a low detection limit. It offers a promising alternative for 5caC detection in clinical samples.
ANALYTICA CHIMICA ACTA
(2023)
Article
Materials Science, Multidisciplinary
B. Munirathinam, J. P. B. van Dam, A. Herrmann, W. D. van Driel, F. De Buyl, S. J. F. Erich, L. G. J. van der Ven, O. C. G. Adan, J. M. C. Mol
Summary: The study explores water diffusion, interfacial ion transport, and delamination behavior in a silicone-coated copper model system, mimicking a typical microelectronics packaging system. The results show the formation of strong hydrogen bonds between water molecules and the silicone network, which plays a crucial role in the system's stability. Additionally, ion transport processes at the silicone/copper interface in a humid atmosphere are investigated using scanning Kelvin probe studies, revealing the importance of exploring ion and water transport for detailed reliability assessment of polymer encapsulated LEDs and microelectronics.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Mingyuan Zhao, Xiaoli Zhao, Ritong Sun, Jian Zhang, Haixia Wang, Chao Shi, Cuiping Ma, Yong Li
Summary: A simple electrochemical DNA biosensor was developed for rapid and specific determination of DNA using electrical potential-assisted hybridization. The biosensor showed rapid detection capability with controlled potential, linear relationship with target DNA concentrations, and good specificity for distinguishing mismatched sequences. It is a promising diagnostic tool for DNA detection.
ANALYTICAL LETTERS
(2022)
Article
Biotechnology & Applied Microbiology
Huicong Wang, Hongru Pian, Lihua Fan, Jian Li, Jifei Yang, Zhi Zheng
Summary: African swine fever (ASF) is a devastating infectious disease affecting domestic pigs and wild boar. Multiple-probe-assisted DNA capture and amplification technology (MADCAT) is a novel method for detecting ASFV directly from whole blood or other complex matrices, which is sensitive, simple, and high-throughput. MADCAT achieves ultrafast and high-throughput detection by specifically capturing the target DNA onto a 96-well plate for subsequent amplification.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Review
Chemistry, Analytical
Comnea-Stancu Ionela Raluca, Jacobus (Koos) Frederick van Staden, Raluca-Ioana Stefan-van Staden
Summary: This article provides a summary of the recent developments in electrochemical sensors targeting atrazine. It discusses the use of nanoscale materials as electrode modifiers and compares different analytical parameters. The difficulties and opportunities for developing new sensing technology are also explored.
ANALYTICAL LETTERS
(2022)
Article
Engineering, Electrical & Electronic
Ummama Saeed, Batool Fatima, Dilshad Hussain, Shan E. Zahra Jawad, Muhammad Imran, Muhammad Najam-ul-Haq
Summary: Prostate cancer is a leading cause of mortality, and the PSA test has limitations in its reliability. This study shows that electrochemical sensing using lanthanum tungstate nanoflakes can enhance the accuracy of prostate cancer detection by detecting leucine and valine, which are potential diagnostic biomarkers for prostate cancer.
IEEE SENSORS JOURNAL
(2023)