Article
Nutrition & Dietetics
Lei Chu, Deqi Su, Hexing Wang, Dilihumaer Aili, Bahegu Yimingniyazi, Qingwu Jiang, Jianghong Dai
Summary: This study aimed to explore the relationship between antibiotic exposures from different sources and type 2 diabetes in middle-aged and older people through urinary antibiotic biomonitoring. The results showed that antibiotic exposure from sources associated with food and drinking water significantly increased the risk of developing type 2 diabetes in middle-aged and older adults.
Article
Endocrinology & Metabolism
Tao Liu, Weihong Liu
Summary: The study found that elevated urinary angiotensinogen levels were associated with a higher risk of stroke events in patients with type 2 diabetes mellitus. Serum angiotensinogen levels, on the other hand, were not significantly associated with the risk. Furthermore, this association was only observed in patients with an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m².
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2022)
Article
Public, Environmental & Occupational Health
Shih-Chun Pan, Ching-Chun Huang, Bing-Yu Chen, Wei-Shan Chin, Yue Leon Guo
Summary: This study aimed to determine whether air pollutants modify the effects of gestational diabetes mellitus (GDM) on the occurrence of diabetes mellitus (DM). The results showed that exposure to high levels of PM2.5 and O-3 increases the risk of DM, and GDM acts synergistically with PM2.5 exposure in DM development.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Szu-Yuan Wu, Wan -Ming Chen, Yi-Chan Chen, Ming-Feng Chiang, Ming-Che Lee, Ruey-Shyang Soong
Summary: This study investigated the association between H1-antihistamine use and hepatocellular carcinoma (HCC) risk in type 2 diabetes mellitus (T2DM) patients without hepatitis B or C virus infection. The results showed that the use of antihistamines significantly reduced the risk of HCC in these patients, and a dose-response relationship was observed.
DIABETES & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Yoo Hyun Um, Tae-Won Kim, Jong-Hyun Jeong, Seung-Chul Hong, Ho-Jun Seo, Kyung-Do Han
Summary: This study found a significant increase in the risk of insomnia in patients with diabetic retinopathy (DR). Men and younger age groups were more vulnerable to insomnia. Sex, age, DM duration, and chronic kidney disease (CKD) status interacted with DR status to further increase the risk of insomnia.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Liyao Fu, Ying Zhou, Jiaxing Sun, Zhenhua Xing, Yongjun Wang, Shi Tai
Summary: Living alone was associated with a significantly higher risk of all-cause mortality in patients with type 2 diabetes compared to those living with one or more adults.
FRONTIERS IN MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
David D. Berg, Filipe A. Moura, Andrea Bellavia, Benjamin M. Scirica, Stephen D. Wiviott, Deepak L. Bhatt, Itamar Raz, Erin A. Bohula, Robert P. Giugliano, Jeong-Gun Park, Mark W. Feinberg, Eugene Braunwald, David A. Morrow, Marc S. Sabatine
Summary: A risk model for atherothrombosis in patients with type 2 diabetes mellitus (T2DM) was developed and validated using data from 42,181 patients. The model identified 16 independent predictors of myocardial infarction (MI) or ischemic stroke (IS). The model performed well in validation and has the potential to improve risk assessment and clinical decision-making.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Yeong-Jang Lin, Chih-Chiang Chien, Chung-Han Ho, Hung-An Chen, Chao-Yu Chen
Summary: Patients newly diagnosed with SLE had a significantly higher risk of developing type 2 diabetes compared to matched controls during the follow-up period, especially among women and low-income SLE patients.
Article
Endocrinology & Metabolism
Meifang Han, Ke Ma, Xiaojing Wang, Weiming Yan, Hongwu Wang, Jie You, Qiuxia Wang, Huilong Chen, Wei Guo, Tao Chen, Qin Ning, Xiaoping Luo
Summary: The study found that COVID-19 patients with type 2 diabetes mellitus (T2DM) were more likely to have lymphopenia, hyperglycemia, and higher levels of certain laboratory parameters. The mortality rate was significantly elevated in diabetic cases, along with higher levels of inflammatory cytokines.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Chin-Hsiao Tseng
Summary: This study did not find a significant effect of vildagliptin on dementia risk, as no significant results were observed in either the unmatched or matched cohort.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Zhenhuang Zhuang, Xue Dong, Jinzhu Jia, Zhonghua Liu, Tao Huang, Lu Qi
Summary: This study found that a healthy sleep pattern is associated with a lower risk of type 2 diabetes mellitus (T2DM). They constructed a metabolomic signature consisting of 153 metabolites, which was strongly correlated with sleep pattern and inversely associated with T2DM risk. Mendelian randomization analysis further indicated a causal relationship between the metabolomic signature and incident T2DM.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Shuo Zhao, Ming-Li Liu, Bing Huang, Fu-Rong Zhao, Ying Li, Xue-Ting Cui, Rong Lin
Summary: This study found that elevated levels of short-chain acylcarnitine C2 were associated with increased risk of cardiovascular disease in patients with type 2 diabetes mellitus and this association remained significant even after adjusting for potential confounders.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Michelle D. Kelsey, Adam J. Nelson, Jennifer B. Green, Christopher B. Granger, Eric D. Peterson, Darren K. McGuire, Neha J. Pagidipati
Summary: Cardiovascular disease is a major concern for individuals with type 2 diabetes mellitus, and aggressive risk factor management is crucial for these high-risk patients. Recommendations and guidelines from professional societies in cardiology, endocrinology, nephrology, and general medicine in the United States and Europe provide guidance on cardiovascular risk reduction for patients with type 2 diabetes mellitus. While there are some differences in risk stratification, treatment targets for low-density lipoprotein-cholesterol and blood pressure, as well as the use of specific medications, overall there is significant alignment across recommendations from different professional societies.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Annika Vestergaard Kvist, Mohamad I. Nasser, Peter Vestergaard, Morten Frost, Andrea M. Burden
Summary: A study in Denmark from 1997 to 2017 found that the incidence rates of fractures were higher in patients with type 1 and type 2 diabetes compared to those without diabetes, except for foot fractures. The incidence of hip fractures decreased by 35.2%, 47.0%, and 23.4% in patients with type 1 diabetes, type 2 diabetes, and without diabetes, respectively, over the last 5 years. However, vertebral fractures increased by 14.8%, 18.5%, and 38.9% in the same groups. After age adjustment, patients with type 1 diabetes still had a higher risk of fractures compared to those without diabetes, while patients with type 2 diabetes had a risk similar to those without diabetes.
Article
Endocrinology & Metabolism
Oscar H. Roa Duenas, Anna C. Van der Burgh, Till Ittermann, Symen Ligthart, M. Arfan Ikram, Robin Peeters, Layal Chaker
Summary: Current evidence suggests an increased risk of type 2 diabetes in individuals with hypothyroidism and lower FT4 levels within the reference range. However, the evidence in this area is still limited and further population-based studies are needed to confirm this association.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)