Article
Medicine, Research & Experimental
Elias B. Nascimento Jr., R. L. Romero, Marcela M. G. B. Dutra, Bernd L. Fiebich, Igor D. G. Duarte, Marcio M. Coelho
Summary: The activation of 5-HT1D and 5-HT7 receptors plays a role in mechanical allodynia induced by 5-HT in mice, while peripheral 5-HT3 receptors have an inhibitory role in the nociceptive response induced by 5-HT or carrageenan.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Cell Biology
Dasa Cizkova, Milan Cizek, Marcela Maloveska, Marta Kmetova, Vladimir Kmet, Dobroslava Bujnakova
Summary: The findings suggest that cell-free L. casei 21L10 supernatant may have potential in attenuating LPS-induced inflammation, inhibiting proliferation, and promoting apoptosis/necrosis. While this study provides insight into using L. casei exoproducts as anti-inflammatory or anti-proliferative agents for gut diseases, further data is required to confirm their efficacy.
Article
Nutrition & Dietetics
Hye Ryeon Yang, Du Hyeon Hwang, Ramachandran Loganathan Mohan Prakash, Jong-Hyun Kim, Il-Hwa Hong, Suk Kim, Euikyung Kim, Changkeun Kang
Summary: This study investigated the effects of ficin, a natural cysteine protease, on fibrin and blood coagulation. The results demonstrated that ficin possessed fibrinolytic activity and could increase prothrombin time and activated partial thromboplastin time. Additionally, ficin shortened the length of infarcted regions in a rat model. Therefore, ficin may serve as a potential alternative for preventing and treating thrombosis-related cardiovascular disorders.
Article
Oncology
Dong Lu, Minghui Yu, Lu Chen, Jianqiang Ye, Liquan Huang, Guangwei Zhu, Bin Lan
Summary: This study found that EB1089 can alleviate LPS-induced inflammation by promoting the expression of VDR, thus reducing apoptosis in intestinal epithelial cells.
ANNALS OF TRANSLATIONAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Xiao-Yan Wang, Wen-Gang Liu, Ai-Sheng Hou, Yu-Xiang Song, Yu-Long Ma, Xiao-Dong Wu, Jiang-Bei Cao, Wei-Dong Mi
Summary: This study found that the dysfunction of EAAT3 is associated with POCD, and riluzole can improve POCD symptoms. This study provides a new therapeutic target for the treatment of POCD.
Article
Biotechnology & Applied Microbiology
Yongjun Yang, Shijun Fan, Qian Chen, Yongling Lu, Yuanfeng Zhu, Xiaoli Chen, Lin Xia, Qianying Huang, Jiang Zheng, Xin Liu
Summary: This study reveals that AuNPs aggravate the hepatotoxic effect of LPS by amplifying ROS-dependent crosstalk in hepatic macrophages and hepatocytes.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Cell Biology
Yumeng Huang, Qian Ji, Yanyan Zhu, Shengqiao Fu, Shuangwei Chen, Liangmei Chu, Yongfei Ren, Yue Wang, Xuan Lei, Jia Gu, Ningzheng Tai, Dadong Liu
Summary: This study found that peripheral 5-HT deficiency can reduce NET formation, alleviate lung inflammation and reduce mortality in sepsis-induced acute lung injury (ALI). It was also found that peripheral 5-HT deficiency can reduce the accumulation of platelets and NETs in the lungs of septic mice. The study uncovers a mechanism by which peripheral 5-HT aggravates sepsis-induced ALI by promoting NET formation in the lungs.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Sumithra Devi Mani, Muthukumar Govindan, Mehanathan Muthamilarasan, Radhakrishnan Nagarathnam
Summary: The study demonstrated that kappa-carrageenan effectively reduced leaf spot disease in tomato plants, inhibited pathogen colonization, enhanced peroxidase activity, and modulated chloroplast proteome expression. This biopolymer shows promise as an inducer of antioxidant defense and a regulator of chloroplast proteome in tomato plants.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Neda Aliabbasi, Zahra Emam-Djomeh, Gholamreza Askari, Maryam Salami
Summary: This study investigated the impact of different kappa-carrageenan concentrations on the gel morphology, physicochemical properties, and release behavior, finding that ideal gel structures and properties can be obtained at certain concentrations. Additionally, the study highlighted the protective effect of kappa-carrageenan/PBA gels on curcumin and their high efficiency in colon-targeting delivery.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Physiology
Qianghu Tang, Baijie Tu, Xuejun Jiang, Jun Zhang, Lulu Bai, Pan Meng, Longbin Zhang, Xia Qin, Bin Wang, Chengzhi Chen, Zhen Zou
Summary: The study found that exposure to CBNPs during pregnancy can increase the sensitivity of offspring to LPS, leading to more severe lung injury symptoms. This intergenerational effect may be related to DNA hypermethylation caused by CBNPs.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2021)
Article
Urology & Nephrology
Lirui Wang, Jiangtao Li, Chen Yu
Summary: The study indicated that SENP3 played a significant regulatory role in LPS-induced AKI, inducing cell apoptosis through protein deSUMOylation and exacerbating damage to renal tubular epithelial cells.
Article
Cell Biology
Zhe Li, Tong Xu, Lin Peng, Xinyu Tang, Qianru Chi, Ming Li, Shu Li
Summary: Nanoplastics pollution poses a huge threat to the ecosystem, and this study found that polystyrene nanoplastics can aggravate lipopolysaccharide-induced renal cell apoptosis through oxidative stress.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Medicine, Research & Experimental
Weiqing Tang, Liu Luo, Baoji Hu, Mingzhi Zheng
Summary: This study demonstrated that butorphanol may alleviate LPS-induced inflammation and apoptosis in cardiomyocytes by upregulating KOR expression, providing a novel insight into the potential therapeutic effects of butorphanol.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
ChoEen Kim, DucDat Le, Mina Lee
Summary: Species of Podocarpus are traditionally used for various treatments, and diterpenoids isolated from P. macrophyllus show potential anti-inflammatory effects against inflammatory bowel disease.
Article
Cell Biology
Qiming Gong, Yan Jiang, Xiuhong Pan, Yanwu You
Summary: Fractalkine (FKN) interacts positively with Wnt/beta-catenin signaling in macrophages, playing a crucial role in LPS-induced acute kidney injury (AKI). FKN overexpression can attenuate LPS-induced macrophage apoptosis and promote their transformation into the beneficial M2 type, suggesting a potential therapeutic target for kidney injury.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2021)
Article
Oceanography
Lina Cai, Xiaoqi Jiang, Xiaojun Yan, Yan Bai, Jianqiang Liu, Menghan Yu, Rong Tang, Jingjing Jiang
Summary: A new method named Shield and Vortex 1-2 (SAV1-2) was established to extract spatial texture information from sun glitter observed from satellites. The method was used to extract sea surface texture detail information around Diaoyu Dao and its affiliated islands. The results showed stable shield effects and Karman vortex streets upstream and downstream of the islands, with the dominant direction of the Kuroshio Current being east. The study also analyzed the changes in water temperature, color, and chlorophyll a concentration.
ACTA OCEANOLOGICA SINICA
(2023)
Article
Agricultural Engineering
Yahui Bo, Ruirui Chu, Danni Sun, Xiangyuan Deng, Chengxu Zhou, Xiaojun Yan, Roger Ruan, Pengfei Cheng
Summary: Microalgae cannot fulfill the bait demand for aquaculture due to limitations in light intensity and other unfavorable conditions. This study selected 6 mixotrophic microalgae and screened for the optimal strains and organic carbon sources. Thalassiosira pseudonana and Chlorella sp. were found to be suitable for mixotrophic culture. When glycerol was added, Thalassiosira pseudonana showed a 1.67-fold increase in maximum cell density compared to the photoautotrophic group, while Chlorella sp. exhibited a 1.69-fold increase with acetic acid. Metabolomic analysis revealed that mixotrophic bait microalgae could promote the accumulation of lipids and amino acids.
BIORESOURCE TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Huan Jiang, Jiabao Hu, Huihui Xie, Man Zhang, Chunyang Guo, Youyi Zhang, Yaya Li, Cheng Zhang, Shanliang Xu, Danli Wang, Xiaojun Yan, Yajun Wang, Xubo Wang
Summary: In this study, the morphological and histological characteristics of the pharyngeal sac in Pampus argenteus were examined using histochemical techniques and electron microscopy. The pharyngeal sac showed unique characteristics such as well-developed muscular walls, weakly keratinized epithelium, numerous goblet cells, and needle-like processes on the papillae. RNA-seq analysis revealed that phenotype-associated genes were upregulated, while genes related to nutrient digestion and absorption were downregulated in the pharyngeal sac.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Wenhao Li, Qiang Gao, Yanjie Hu, Yutong Shi, Xiaojun Yan, Lijian Ding, Shan He
Summary: Benzofuran-containing compounds are a promising scaffold with a wide range of pharmacological properties for drug development. A new benzofuran derivative, dibetanide, was discovered and characterized, featuring an unusual conjugated triene side chain. The structure and absolute configuration of the compound were determined using experimental and computational methods. The compound exhibited inhibitory activity against Botrytis cinerea, suggesting potential antibacterial properties.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Environmental Sciences
Siwen Zhang, Xiaohui Chen, Zongjun Ji, Xiaojun Yan, Kunpeng Kong, Yuanyang Cai, Qichao Zhu, Muhammad Atif Muneer, Fusuo Zhang, Liangquan Wu
Summary: Aluminum (Al) toxicity is a serious threat to root formation and crop growth due to soil acidification. This study focused on the effect of Al3+ on citrus roots in acidified red soil. The results showed that rapid soil acidification occurred in pomelo orchards, and optimized fertilization and liming treatments effectively reduced Al toxicity in roots and increased yield by improving soil pH and base saturation. Structural equation modeling confirmed the importance of increasing soil pH and base saturation while decreasing exchangeable Al for citrus production in acidic soil.
LAND DEGRADATION & DEVELOPMENT
(2023)
Article
Political Science
Xiaojun Yan, La Li
Summary: In this article, we examine how autocratic regimes, in particular China, use political propaganda to facilitate policy reversals of major significance. Through analyzing extensive propaganda materials, we find that the Chinese Communist Party employs a systematic, precise, multi-dimensional, and multi-layered discursive engineering project to reverse its policies effectively. This coordinated maneuver of state narrative is key in achieving the smooth and successful policy reversal.
GOVERNANCE-AN INTERNATIONAL JOURNAL OF POLICY ADMINISTRATION AND INSTITUTIONS
(2023)
Article
Biochemistry & Molecular Biology
Minhui Xu, Jiji Li, Baoying Guo, Kaida Xu, Yingying Ye, Xiaojun Yan
Summary: In this study, a new sequence was used to investigate the classification systems and phylogenetic relationships within Mytiloidea. The mitogenome of Vignadula atrata was analyzed, showing a close relationship with Bathymodiolus and novel gene rearrangements within Mytiloidea. This study provides valuable insights into the taxonomic histories and evolutionary relationships of marine mussels.
BIOCHEMICAL GENETICS
(2023)
Article
Agricultural Engineering
Xia Xiao, Yang-Yang Liu, Xiao-Jun Yan, Xiao-Na Wang, Bin-Yuan Hu, Song Chen, Yan-Yan Zhu, Zhao-Jie Wang, Tian-Zhen Xie, Ying-Jie He, Li-Xing Zhao, Yun-Li Zhao, Xiao-Dong Luo
Summary: Allium chinense G. Don, known as Ganoderma of vegetables, has been used historically to treat blood stasis syndrome and reduce brain damage caused by reduced oxygen-carrying capacity. The anti-hypoxic effect of A. chinense was investigated using a mouse model of cerebral anoxia, and 16 compounds were isolated, showing potential anoxia-tolerant activity in vitro. These compounds also regulated oxidative stress markers and suppressed the expression of inflammatory proteins. This study provides a new nutritional strategy for A. chinense against cerebral anoxia and altitude illness.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Jianquan Song, Hejing Zhao, Linxin Zhang, Zheng Li, Jichang Han, Chengxu Zhou, Jilin Xu, Xiaohui Li, Xiaojun Yan
Summary: This study revealed that the heat shock transcription factor PtHSF1 positively regulates the synthesis of triacylglycerol and fucoxanthin in Phaeodactylum tricornutum. Overexpression of PtHSF1 increased the contents of triacylglycerol and fucoxanthin and upregulated key enzyme genes involved in their biosynthesis pathways. Gene silencing of PtHSF1 had the opposite effect. This study provided insights into the regulation mechanisms of PtHSF1-mediated triacylglycerol and fucoxanthin synthesis.
PLANT AND CELL PHYSIOLOGY
(2023)
Article
Plant Sciences
Xiaojun Yan, Delian Ye, Yafu Tang, Muhammad Atif Muneer, Peter Christie, Congyue Tou, Weidong Xu, Bingrong Shen, Jinxian Xu, Jiangzhou Zhang
Summary: Quantitative analysis using life cycle assessment was conducted to assess the environmental impacts of plum production in Zhao'an county, southeast China. The farms were categorized into four groups based on yield and environmental impacts. Excessive fertilizer application was identified as the main source of environmental impacts, and reducing fertilizer usage without compromising plum yield could be achieved by studying farms with high yield and low environmental impact. These results provide an important foundation for improving plum production management and promoting "green" agricultural development by reducing environmental impacts.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Environmental Sciences
Rong Tang, Lina Cai, Xiaojun Yan, Xiaomin Ye, Yuzhu Xu, Jie Yin
Summary: The response of environmental factors in Zhoushan Fishery to Typhoon In-fa was analyzed using satellite and reanalysis data. The study revealed that the typhoon caused a decrease in sea surface temperature and an overall decrease in sea surface salinity. The concentration of chlorophyll a initially decreased and then increased due to the typhoon's effect on phytoplankton growth. These changes in environmental factors have significant impacts on fish behavior and community composition in fisheries.
Article
Genetics & Heredity
Kaifen Zhang, Yongdong Zhou, Weihua Song, Lihua Jiang, Xiaojun Yan
Summary: In this study, RAD-seq analysis was performed on 54 individuals of Larimichthys crocea to investigate its genetic structure and diversity at the genome level. The study revealed distinct genetic differentiation between the large yellow croaker populations in the Ningde and Zhoushan coastal waters. Different genetic diversity indices indicated a differentiation trend between wild and farmed populations in Ningde. Genetically differentiated genomic regions and genes related to fatty acid metabolism and growth were identified. These findings contribute to the understanding of genetic differentiation and adaptation in Larimichthys crocea, and provide a theoretical basis for the conservation and restoration of its genetic resources.
Article
Chemistry, Physical
Shengwen Zou, Jun Kang, Yuzheng Zhang, Mingjing Qi, Xiaojun Yan, Xiaoliang Zhang, Jianmei Huang
Summary: In this work, transition metal nickel ion (Ni2+) was introduced into CsPbI3 nanocrystals (NCs) to stabilize their black phase. The optimized CsPbI3 NCs film exhibited a record photoactive black-phase stability time of 54 hours. The doped Ni2+-CsPbI3 NCs solutions maintained bright red emission even after vigorous stirring and long-term storage, showing improved stability and photoluminescence quantum yield.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Fisheries
Sentao Chen, Peng Shi, Qingkai Feng, Xiaoting Qiu, Jilin Xu, Xiaojun Yan, Chengxu Zhou
Summary: In this study, a new C-type lectin (Rpcl) was identified from the Manila clam Ruditapes philippinarum, and its potential role in feeding and feed selection was investigated. The results showed that Rpcl had a carbohydrate recognition domain (CRD) and could selectively agglutinate with different microalgae. Feeding experiments revealed that Rpcl expression in the lip and gill of the clam fed with certain microalgae exhibited a significant upward trend with the change of time.
Article
Chemistry, Inorganic & Nuclear
Wenfeng Hao, Xiaojun Yan, Xiliang Guo, Wentao Wang, Taihong Yan, Jia-Nan Zhang, Wenfu Yan
Summary: Cs-137(+) is the main radioactive nuclide in nuclear wastewater. The efficient and fast removal of radioactive Cs+ from wastewater is essential for the safe use of nuclear energy and human health. In this study, a green and facile synthesis method of low-silica CHA zeolite with exceptional selectivity and deep removal ability for radioactive Cs-137(+) from real nuclear power wastewater was reported.
INORGANIC CHEMISTRY FRONTIERS
(2023)