期刊
MECHANISMS OF DEVELOPMENT
卷 145, 期 -, 页码 26-31出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mod.2017.03.005
关键词
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资金
- Francis Crick Institute - Cancer Research UK [FC001051]
- UK Medical Research Council [FC001051]
- Wellcome Trust [FC001051, WT098326MA]
- IST Austria
- European Research Council under Horizon research and innovation programme [680037]
- The Francis Crick Institute [10054, 10051] Funding Source: researchfish
- European Research Council (ERC) [680037] Funding Source: European Research Council (ERC)
By applying methods and principles from the physical sciences to biological problems, D'Arcy Thompson's On Growth and Form demonstrated how mathematical reasoning reveals elegant, simple explanations for seemingly complex processes. This has had a profound influence on subsequent generations of developmental biologists. We discuss how this influence can be traced through twentieth century morphologists, embryologists and theoreticians to current research that explores the molecular and cellular mechanisms of tissue growth and patterning, including our own studies of the vertebrate neural tube. (C) 2017 Elsevier B.V. All rights reserved.
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