Article
Biochemistry & Molecular Biology
Sowmya P. Mohandas, Linu Balan, Jayanath Gopi, B. S. Anoop, Sooraj P. Mohan, Rosamma Philip, Sherine Sonia Cubelio, I. S. Bright Singh
Summary: PHBV films produced from Bacillus cereus MCCB 281 exhibit moderate surface roughness and hydrophilicity, showing good cell attachment and proliferation of L929 fibroblasts, as well as excellent blood compatibility for potential use in tissue engineering and medical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Zexian Xu, Yali Li, Dian Xu, Li Li, Yaoxiang Xu, Liqiang Chen, Yanshan Liu, Jian Sun
Summary: Nano-hydroxyapatite (nHA) is enhanced with fluorinated graphene oxide (FG) to improve its formability, mechanical properties, antimicrobial activity, and clinical application. The nHA/FG composite scaffold shows improved mechanical properties, with a uniform distribution of FG. The composite scaffold exhibits satisfactory cytocompatibility and antibacterial properties.
Article
Biophysics
S. Thanka Rajan, Mitun Das, A. Arockiarajan
Summary: The study demonstrates that the development of niobium and niobium oxide thin films on Mg alloys using sputtering technique can improve the corrosion resistance and biocompatibility of the alloys. The thin-film coated Mg alloys exhibited good corrosion resistance and cell proliferation capability.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Review
Materials Science, Ceramics
S. Thanka Rajan, B. Subramanian, A. Arockiarajan
Summary: Thin films are an ideal surface treatment for enhancing the properties of permanent implant materials, such as biodegradation resistance, mechanical strength, and biocompatibility. The success of implants in clinical practice depends on the interaction between cells and material surfaces, and recent developments in biomaterials have introduced various coatings to address these issues.
CERAMICS INTERNATIONAL
(2022)
Article
Engineering, Biomedical
Nikhil Anand, Neha Mehrotra, Kaushik Pal
Summary: In this study, a biodegradable Zn-1Mg-1Cu-1HA (ZHA) and Zn-1Mg-1Cu-1ZrO2 (ZZR) composite was created using the stir-casting process and enhanced with a ceramic composite coating by electrodeposition technique. Microstructural analysis revealed uniform distribution of fine MgZn2 and CuZn2 phases in an α-Zn matrix. The mechanical test confirmed high tensile and compressive properties of the ZZR composite, along with low corrosion rate and degradation rate, and good cell viability. Overall, the coated ZZR composite shows promise as a material for implant applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Materials Science, Ceramics
Marzena Fandzloch, Weronika Bodylska, Adam W. Augustyniak, Katarzyna Roszek, Anna Jaromin, Anna Lukowiak
Summary: Highly bioactive binary and ternary nanoparticles, including xerogel (88SiO2-12CaO) and glass (69SiO2-25CaO-6P2O5), greatly enhanced the formation process of hydroxyapatite. The deposition of a HA layer on the glasses was analyzed by various techniques and a superior apatite-mineralization ability was achieved. The most promising candidate with comparable bioactivity to Bioglass is solvXG78P6.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Physical
Wojciech Zieba, Joanna Czarnecka, Tomasz Rusak, Monika Zieba, Artur P. Terzyk
Summary: The study presents the cytotoxicity of single-walled carbon nanohorn (SWCNH) oxidized materials on A549 and HDF cell lines, as well as the hemocompatibility on human and porcine blood samples. Results show correlation between specific surface area of materials and platelet aggregation, and the I-D/I-G ratio from Raman spectra with hemoglobin release from erythrocytes.
Article
Engineering, Mechanical
S. Karthikeyan, B. Mohan, S. Kathiresan, G. Anbuchezhiyan
Summary: In the Rotational Magnetorheological Abrasive Flow Finishing (R-MRAFF) process, Magnetic Field Intensity (MFI) plays a crucial role in the formation of ferrous chains for finishing. Three different MFI values were chosen for finishing on Stainless Steel 316L (SS 316L), showing improvements in wettability, corrosion resistance, and hemocompatibility. Increasing MFI values led to hydrophilic surface, reduced corrosion rate, and decreased platelet adhesion on SS 316L implants.
SURFACE TOPOGRAPHY-METROLOGY AND PROPERTIES
(2022)
Article
Chemistry, Physical
S. Thanka Rajan, Mitun Das, A. Arockiarajan
Summary: In this study, tantalum oxide thin films were deposited onto the surface of AZ31B alloy using the sputtering process, and their biocompatibility and corrosion resistance were evaluated. The results showed that the Ta-based thin films significantly enhanced the corrosion resistance of the magnesium alloy, exhibited good bioactivity, and had good hemocompatibility.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Nanoscience & Nanotechnology
Giuseppa Biddeci, Gaetano Spinelli, Marina Massaro, Serena Riela, Paola Bonaccorsi, Anna Barattucci, Francesco Di Blasi
Summary: This study aimed to investigate the in vitro mechanism of halloysite nanotubes (HNTs) internalization into living cells using phagocytic and non-phagocytic cell lines. The results showed that the internalization process of HNTs is energy-dependent, with different characteristics in non-phagocytic and phagocytic cells. The study also identified the involvement of clathrin-dependent and independent endocytosis in non-phagocytic cells, and the participation of microtubules in phagocytic cells in the cellular trafficking of HNTs.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Materials Science, Ceramics
Subha Balakrishnan, Varun Prasath Padmanabhan, Ravichandran Kulandaivelu, T. S. Sankara Narayanan Nellaiappan, Suresh Sagadevan, Suriati Paiman, Faruq Mohammad, Hamad A. Al-Lohedan, Prasanna Kumar Obulapuram, Won Chun Oh
Summary: This study investigated the characteristics of hydroxyapatite (HAP) doped with Fe, forming Fe-HAP composites with superior properties compared to pure HAP. Among the Fe-HAP composites, 10Fe-HAP exhibited the best performance, with increased physicochemical and biological properties attributed to interactions between Ca2+ and Fe-doped HAP.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Ceramics
Sikta Panda, Mizuki Kazama, Takahiro Kawai, Chandan Kumar Biswas, Subhankar Paul
Summary: Ti alloy sheets were bio-activated using a two-step thermo-chemical treatment followed by biomimetic mineralization. The resulting hydroxyapatite layer improved mechanical properties, corrosion resistance, cytocompatibility, and bactericidal activity.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Paper & Wood
Muhammad Wajid Ullah, Fazli Subhan, Sehrish Manan, Mazhar Ul-Islam, Khulood Fahad Alabbosh, Tahseen Kamal, Khalid Ali Khan, Jun Liu, Guang Yang, Jianzhong Sun
Summary: This study investigated the effect of acetylated bacterial cellulose (ABC) on its biological performance. Acetylation improved the structural properties of ABC, resulting in enhanced fiber arrangement, optical transparency, hydrophobicity, mechanical strength, and thermal stability. The ABC scaffolds showed improved cell adhesion and proliferation, 3D cell growth pattern, hemocompatibility, and protein adsorption, indicating their potential use in tissue engineering and regenerative medicines.
Article
Materials Science, Paper & Wood
Ioana Cristina Marinas, Gratiela Gradisteanu Pircalabioru, Eliza Oprea, Elisabeta-Irina Geana, Irina Zgura, Cosmin Romanitan, Elena Matei, Marian Angheloiu, Oana Brincoveanu, Mihaela Georgescu, Mariana Carmen Chifiriuc
Summary: This study aimed to develop a multifunctional bioactive wound dressing using two invasive plant species. The researchers successfully functionalized a microporous cellulosic sponge from Gleditsia triacanthos pods and added Phytolacca americana fruit extract for its bioactive properties. The sponge demonstrated controlled release of bioactive compounds, promoted wound healing, inhibited microbial growth, and had anti-inflammatory effects.
Article
Polymer Science
Ana M. Pinilla-Torres, Paola Y. Carrion-Garcia, Celia N. Sanchez-Dominguez, Hugo Gallardo-Blanco, Margarita Sanchez-Dominguez
Summary: The modification of branched polyethyleneimine with mesquite gum improved its hemocompatibility for biomedical applications. The synthesized copolymer showed good buffer capacity, non-hemolytic properties, and potential for use in transfection, polymeric nanoparticles, and biomaterials.
Article
Engineering, Biomedical
Ludovica Parisi, Federico Rivara, Camila A. Costa, Rodriguo P. F. Abuna, Daniela B. Palioto, Guido M. Macaluso
Summary: The study introduces aptamers to control biomaterial surface bioactivity, promoting platelet activation in vitro and bone regeneration in vivo, showing a potential for enhancing periodontal regenerative therapies.
BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Physical
Chuan-Pei Lee, Bayu-Tri Murti, Po-Kang Yang, Francesca Rossi, Carlo Carraro, Roya Maboudian
Summary: A cobalt oxide-decorated silicon carbide nano-tree array electrode was synthesized for micro-supercapacitor applications, showing extremely hydrophilic surface characteristics for enhanced charge transfer at the electrode/aqueous electrolyte interface. The well-standing architecture provided a directional charge transport route along the length of SiC nanowires, leading to excellent areal capacitance and stability in cyclic voltammetry measurements for 2000 cycles at a high scan rate of 150 mV s(-1).
Article
Multidisciplinary Sciences
Paola Lagonegro, Stefano Rossi, Nicolo Salvarani, Francesco Paolo Lo Muzio, Giacomo Rozzi, Jessica Modica, Franca Bigi, Martina Quaretti, Giancarlo Salviati, Silvana Pinelli, Rossella Alinovi, Daniele Catalucci, Francesca D'Autilia, Ferdinando Gazza, Gianluigi Condorelli, Francesca Rossi, Michele Miragoli
Summary: Myocardial infarction leads to millions of deaths worldwide, mainly due to fibrillation originating from damaged areas of the left ventricle. Conventional medical interventions can restore blood flow but fail to address the bioelectrical alteration caused by the infarct. Researchers have developed biocompatible silicon carbide nanowires that can connect isolated beating cardiomyocytes, restoring physiological cell-cell conductance. By injecting these nanowires into the infarcted regions, impulse propagation can be rapidly reinstated, improving electrogram parameters and conduction velocity. This nanomedical intervention shows promise in reducing ventricular arrhythmia after acute myocardial infarction.
NATURE COMMUNICATIONS
(2022)
Article
Information Science & Library Science
Carlo Galli, Maria Teresa Colangelo, Stefano Guizzardi
Summary: The introduction of abstracts to replace article summaries in 1990 acknowledged the changing trends in linguistic reporting. Language used in article abstracts and summaries became more informal in the 1970s, with a shift towards a greater emphasis on the future and language indicating author confidence.
LEARNED PUBLISHING
(2022)
Article
Chemistry, Physical
Valentina Zannier, Ang Li, Francesca Rossi, Sachin Yadav, Karl Petersson, Lucia Sorba
Summary: In order to use III-V compound semiconductors as active channel materials in advanced electronic and quantum devices, it is important to achieve a good epitaxial growth on silicon substrates. The study reports on the selective-area growth of GaP/InGaP/InP/InAsP buffer layer nanotemplates on GaP substrates which are closely lattice-matched to silicon, suitable for the integration of in-plane InAs nanowires. The results demonstrate that a growth sequence of thin layers with progressively increasing lattice parameters is effective to efficiently relax the strain and eventually obtain high quality in-plane InAs nanowires on large lattice-mismatched substrates.
Article
Chemistry, Multidisciplinary
Claudio Ferrari, Giovanni Attolini, Matteo Bosi, Cesare Frigeri, Paola Frigeri, Enos Gombia, Laura Lazzarini, Francesca Rossi, Luca Seravalli, Giovanna Trevisi, Riccardo Lolli, Lucrezia Aversa, Roberto Verucchi, Nahida Musayeva, Muhammad Alizade, Sevinj Quluzade, Teimur Orujov, Francesco Sansone, Laura Baldini, Francesco Rispoli
Summary: In this study, amino-functionalized carbon nanotubes were used to produce resistive sensors for detecting nitroaromatic explosives through their interaction with vapor. The sensors demonstrated simple construction, low power consumption, and potential for portable device preparation.
Article
Computer Science, Interdisciplinary Applications
Carlo Galli, Roberto Sala, Maria Teresa Colangelo, Stefano Guizzardi
Summary: A literature search revealed the use of a common template in the reporting of in vitro testing of natural anti-inflammatory compounds. The template was observed in 65 reports published between 2008 and 2019, with distinct hallmarks in data plotting, endpoints, and graphical representation. However, no new reports following this format were published in 2020. The consistent format template may improve report readability, but further examination is needed to understand its rationale, validity of endpoints, and reasons for abandonment.
Article
Chemistry, Physical
Lorenzo Peri, Domenic Prete, Valeria Demontis, Valentina Zannier, Francesca Rossi, Lucia Sorba, Fabio Beltram, Francesco Rossella
Summary: In this study, a significant reduction in thermal conductivity in III-V semiconductor nanowires was achieved by introducing periodic crystal-lattice twin planes. These twinning superlattice nanowires exhibited improved thermoelectric properties, making them promising nanomaterials for high-efficiency thermoelectric energy harvesting.
Article
Chemistry, Multidisciplinary
Omer Arif, Valentina Zannier, Francesca Rossi, Diego De Matteis, Katharina Kress, Marta De Luca, Ilaria Zardo, Lucia Sorba
Summary: Nanowire geometry offers the possibility of obtaining semiconductor heterostructures that are not achievable in planar systems, allowing for the exploration of new optical transitions and vibrational properties. High-quality superlattice nanowires have shown improved thermoelectric properties and the potential for engineering photonic and phononic properties at the nanoscale.
Article
Optics
Matteo L. Zaffalon, Francesca Cova, Mingming Liu, Alessia Cemmi, Ilaria Di Sarcina, Francesca Rossi, Francesco Carulli, Andrea Erroi, Carmelita Roda, Jacopo Perego, Angiolina Comotti, Mauro Fasoli, Francesco Meinardi, Liang Li, Anna Vedda, Sergio Brovelli
Summary: Radiation detection is crucial in various fields, and CsPbBr3 nanocrystals have shown exceptional radiation hardness under high doses of radiation. By fluorination treatment, the scintillation efficiency of CsPbBr3 has been significantly enhanced, while maintaining high radiation hardness.
Article
Chemistry, Multidisciplinary
Maria Teresa Colangelo, Maria Luisa Vicedomini, Silvana Belletti, Paolo Govoni, Stefano Guizzardi, Carlo Galli
Summary: A polynucleotide-hyaluronic acid compound shows promise in improving soft tissue regeneration, but more advanced 3D culture models are needed to better understand its effects on target cells.
APPLIED SCIENCES-BASEL
(2023)
Article
Information Science & Library Science
Stefano Guizzardi, Maria Teresa Colangelo, Prisco Mirandola, Carlo Galli
Summary: The present study used a proprietary software, LIWC 2022, to assess the degree of narrativity in scientific abstracts obtained from Pubmed. By applying pre-set dictionaries, the software attributed scores for Staging, Plot Progression, and Cognitive Tension to the texts. The researchers found that abstracts in the biomedical literature do not exhibit the typical narrative arc observed in novels, but they do possess a diverse yet reproducible narrative pattern. Reviews tend to have a higher degree of narrativity compared to primary studies.
Article
Cell & Tissue Engineering
Stefano Guizzardi, Maria Teresa Colangelo, Prisco Mirandola, Carlo Galli
Summary: Research shows that artificial intelligence can provide smart tools to screen massive amounts of literature and automatically identify research topics, which is of great significance for the development of bone regeneration.
REGENERATIVE MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
L. Seravalli, M. Bosi, P. Fiorenza, S. E. Panasci, D. Orsi, E. Rotunno, L. Cristofolini, F. Rossi, F. Giannazzo, F. Fabbri
Summary: The use of gold nanoparticles in the chemical vapor deposition growth of two-dimensional molybdenum disulfide has been shown to influence the synthesis of large monolayer MoS2 flakes, as well as modify the optical and electronic properties of MoS2 triangular domains. This suggests a potential method for localized synthesis of two-dimensional materials with improved properties.
NANOSCALE ADVANCES
(2021)
Article
Chemistry, Multidisciplinary
A. Portone, L. Bellucci, D. Convertino, F. Mezzadri, G. Piccinini, M. A. Giambra, V. Miseikis, F. Rossi, C. Coletti, F. Fabbri
Summary: By employing single crystalline graphene to modify the sulfurization dynamics of copper foil, large-area Cu9S5 crystals could be deterministically synthesized, enabling the epitaxial growth of layered materials with different crystalline symmetries and the synthesis of heterostructures with a large lattice constant mismatch.
NANOSCALE ADVANCES
(2021)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)