期刊
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 77, 期 -, 页码 1290-1301出版社
ELSEVIER
DOI: 10.1016/j.msec.2017.03.279
关键词
Clinical application; Extracellular matrix; Decellularized tendon; Recellularization
资金
- National Nature Science Fund of China [81472064]
- Natural Science Fund of Zhejiang Province [Z15H060002, LY17H010003]
- funds of Science and Technology Dept Intent of Zhejiang Province [2009C03014-1]
- Zhejiang Xinmiao Talents Program [2016R413035, 2015R413021]
Tendon injuries impose significant clinical burdens on healthcare systems worldwide. At present, no therapeutic methods can cure tendon injuries in an ideal manner. With the development and improvement of decellularization technology, tendon extracellular matrix (ECM) can develop into novel scaffolds with potential for repairing injured tendons. Proper agents and decellularization protocols were developed to obtain tendon ECMs, and the method used to recellularize the tendon ECM was explored to create bio-functional neotendons for transplants. Further, preliminary testing was done to evaluate the reparative capacity of decellularized tendon scaffolds (DTSs). Here, we assess developments in tendon decellularization and recellularization processes, as well as the possibility for advancing DTSs into clinical applications based on recent findings. (C) 2017 Published by Elsevier B.V.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据