期刊
MACROMOLECULAR MATERIALS AND ENGINEERING
卷 302, 期 11, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mame.201700258
关键词
antimicrobial surface; biomimetic surface; polyhydroxyalkanoate; surface modification
资金
- National Natural Science Foundation of China [51572110, 31470934]
- Natural Science Foundation of Guangdong Province of China [2016A030313085]
- Science and Technology Planning Project of Guangdong Province of China [2015A020212025]
- Key Project of Guangdong Science and Technology Program [2014B010105007]
Biomaterials for in vivo application should induce positive interaction with various histocytes and inhibit bacteria inflection as well. Cells and/or bacteria response to the extracellular environment is therefore the basic principle to design the biomaterials surface in order to induce the specific biomaterial-biological interaction. Polyhydroxyalkanoate (PHAs) are of growing interests because of their natural origin, biodegradability, biocompatibility, and thermoplasticity; however, quite inert and intrinsic hydrophobic characteristics have hindered their extensive usage in medical applications. Surface modification of PHAs tailors the chemistry, wettability, and topography without altering the bulk properties, and introduces specific proteins/peptides and/or antibacterial agents to mediate cell-matrix interactions. This review describes the recent developments on the surface modification of PHAs to construct cell compatible and antibacterial surfaces.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据