O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies

Molecular insights into regulation of JAK2 in myeloproliferative neoplasms

(2015) O. Silvennoinen et al.   BLOOD

The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours

(2015) S J Thomas et al.   BRITISH JOURNAL OF CANCER

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells

(2015) PARUNYA CHAIYAWAT et al.   ONCOLOGY REPORTS

Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

(2015) Can Küçük et al.   Nature Communications

Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells

(2015) Axel Weber et al.   Cancers

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

(2014) M Girardot et al.   ONCOGENE

Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis

(2014) Anindya Chatterjee et al.   Cell Reports

Aberrant O-GlcNAcylated Proteins: New Perspectives in Breast and Colorectal Cancer

(2014) Parunya Chaiyawat et al.   Frontiers in Endocrinology

O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

(2013) H. M. Itkonen et al.   CANCER RESEARCH

PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis

(2013) A Berger et al.   LEUKEMIA

Cytokine regulation of mammary gland development and epithelial cell functions through discrete activities of Stat proteins

(2013) Bernd Groner et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer

(2013) THANONG PHUEAOUAN et al.   ONCOLOGY REPORTS

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2V617F in mice

(2012) C. Walz et al.   BLOOD

Janus Kinase Deregulation in Leukemia and Lymphoma

(2012) Edwin Chen et al.   IMMUNITY

Discovery ofO-GlcNAc-modified Proteins in Published Large-scale Proteome Data

(2012) Hannes Hahne et al.   MOLECULAR & CELLULAR PROTEOMICS

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

(2012) Oliver Hantschel et al.   Nature Chemical Biology

Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development

(2012) Clifford Liongue et al.   PLoS One

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation

(2010) K. Friedbichler et al.   BLOOD

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective

(2010) Nicolas Guex et al.   ELECTROPHORESIS

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

(2010) K. E. Wellen et al.   GENES & DEVELOPMENT

Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

(2010) Y Shi et al.   LEUKEMIA

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1

(2010) S A Caldwell et al.   ONCOGENE

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease

(2009) G. Li et al.   BLOOD

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2

(2008) F. Grebien et al.   BLOOD

The different functions of Stat5 and chromatin alteration through Stat5 proteins

(2008) Jan-Wilhelm Kornfeld   Frontiers in Bioscience-Landmark

Regulation of theO-Linked β-N-Acetylglucosamine Transferase by Insulin Signaling

(2008) Stephen A. Whelan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH