A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target

Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid–Induced Macrophage Cell Death through Enhancing Ceramide Production

(2016) Yuwen Zhang et al.   JOURNAL OF IMMUNOLOGY

Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells

(2016) F Yan et al.   LEUKEMIA

The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2′-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells

(2015) Fei Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation

(2015) X N Gao et al.   LEUKEMIA

Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells

(2014) Ulrike Harjes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of fatty acid binding protein 4 is involved in the cell growth of oral squamous cell carcinoma

(2014) DOKSA LEE et al.   ONCOLOGY REPORTS

Restoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation

(2014) F Yan et al.   Cell Death & Disease

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

(2013) F. Wang et al.   SCIENCE

FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women

(2011) Ximena Terra et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity

(2011) Hong Lan et al.   JOURNAL OF LIPID RESEARCH

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells

(2010) Mary YK Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Cytidine deaminases: AIDing DNA demethylation?

(2010) E. L. Fritz et al.   GENES & DEVELOPMENT

Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia

(2010) S Deneberg et al.   LEUKEMIA

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

(2010) Michael G Kharas et al.   NATURE MEDICINE

Evidence for a Relationship between VEGF and BMI Independent of Insulin Sensitivity by Glucose Clamp Procedure in a Homogenous Group Healthy Young Men

(2010) Michaela Loebig et al.   PLoS One

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

(2009) R. Garzon et al.   BLOOD

Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients

(2009) K. Hancke et al.   BREAST CANCER RESEARCH AND TREATMENT

Involvement of serum vascular endothelial growth factor family members in the development of obesity in mice and humans☆

(2009) Javier Gómez-Ambrosi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Emerging Functions and Mechanisms of Mammalian Fatty Acid–Binding Proteins

(2008) Judith Storch et al.   Annual Review of Nutrition

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

(2008) K. H. Metzeler et al.   BLOOD

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

(2008) Masato Furuhashi et al.   NATURE REVIEWS DRUG DISCOVERY