T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

Homing to solid cancers: a vascular checkpoint in adoptive cell therapy using CAR T-cells

(2016) Ann Ager et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Armored CAR T-cells: utilizing cytokines and pro-inflammatory ligands to enhance CAR T-cell anti-tumour efficacy

(2016) Oladapo O. Yeku et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting the tumour profile using broad spectrum chimaeric antigen receptor T-cells

(2016) Shoba A. Navai et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Optimizing T-cell receptor gene therapy for hematologic malignancies

(2016) Emma C. Morris et al.   BLOOD

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

(2016) Kole T. Roybal et al.   CELL

Mechanisms of T cell organotropism

(2016) Hongmei Fu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Homing in on the Sweet Side of Immune Checkpoint Biology

(2016) Steven R. Barthel et al.   IMMUNITY

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

(2016) Roberto Tinoco et al.   IMMUNITY

New Strategies for the Treatment of Solid Tumors with CAR-T Cells

(2016) Hao Zhang et al.   International Journal of Biological Sciences

Imprinting of Skin/Inflammation Homing in CD4+T Cells Is Controlled by DNA Methylation within theFucosyltransferase 7Gene

(2016) Matthias Pink et al.   JOURNAL OF IMMUNOLOGY

Associations of Insulin and IGFBP-3 with Lung Cancer Susceptibility in Current Smokers

(2016) Gloria Y. F. Ho et al.   JNCI-Journal of the National Cancer Institute

Safety of targeting tumor endothelial cell antigens

(2016) Samuel C. Wagner et al.   Journal of Translational Medicine

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

(2016) Benjamin P. Kleinstiver et al.   NATURE

Prospects for gene-engineered T cell immunotherapy for solid cancers

(2016) Christopher A Klebanoff et al.   NATURE MEDICINE

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

(2016) Danny N. Khalil et al.   Nature Reviews Clinical Oncology

Tumour-infiltrating lymphocytes in melanoma prognosis and cancer immunotherapy

(2016) Nayoung Lee et al.   PATHOLOGY

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells

(2016) Brad Dykstra et al.   STEM CELLS

Associations of Insulin and IGFBP-3 with Lung Cancer Susceptibility in Current Smokers

(2016) Gloria Y. F. Ho et al.   JNCI-Journal of the National Cancer Institute

Effector, Memory, and Dysfunctional CD8+T Cell Fates in the Antitumor Immune Response

(2016) John Reiser et al.   Journal of Immunology Research

Producer T cells: Using genetically engineered T cells as vehicles to generate and deliver therapeutics to tumors

(2016) Alexander K. Tsai et al.   OncoImmunology

Role of Radiation Therapy as Immune Activator in the Era of Modern Immunotherapy for Metastatic Malignant Melanoma

(2015) Derick Okwan-Duodu et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells

(2015) A. Lo et al.   CANCER RESEARCH

Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice

(2015) X. Liu et al.   CANCER RESEARCH

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

(2015) H. G. Caruso et al.   CANCER RESEARCH

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

(2015) Sonja Kleffel et al.   CELL

Tumor-Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma

(2015) L. Zhang et al.   CLINICAL CANCER RESEARCH

Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis

(2015) Jasmeen S Merzaban et al.   GLYCOBIOLOGY

Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice

(2015) Zhenghui Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advanced research on vasculogenic mimicry in cancer

(2015) Lili Qiao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

From mice to humans: developments in cancer immunoediting

(2015) Michele W.L. Teng et al.   JOURNAL OF CLINICAL INVESTIGATION

Diverse Inflammatory Cytokines Induce Selectin Ligand Expression on Murine CD4 T Cells via p38α MAPK

(2015) Mark E. Ebel et al.   JOURNAL OF IMMUNOLOGY

CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo

(2015) Francisco Velázquez et al.   JOURNAL OF IMMUNOLOGY

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential

(2015) Erika M. Yazawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?

(2015) Samuel C. Wagner et al.   Journal of Translational Medicine

A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer

(2015) Mythili Koneru et al.   Journal of Translational Medicine

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes

(2015) Ignazio Caruana et al.   NATURE MEDICINE

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Rationally engineered Cas9 nucleases with improved specificity

(2015) I. M. Slaymaker et al.   SCIENCE

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

(2015) J. David Peske et al.   Nature Communications

Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints

(2015) M. E. Mikucki et al.   Nature Communications

Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer

(2015) A. W. Lund et al.   Cancer Discovery

T-cell-based Immunotherapy: Adoptive Cell Transfer and Checkpoint Inhibition

(2015) R. Houot et al.   Cancer Immunology Research

PD-1 Restrains Radiotherapy-Induced Abscopal Effect

(2015) S. S. Park et al.   Cancer Immunology Research

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications

(2015) Aitziber Buqué et al.   OncoImmunology

Understanding high endothelial venules: Lessons for cancer immunology

(2015) Ann Ager et al.   OncoImmunology

The diagnostic value of serum carcino-embryonic antigen, alpha fetoprotein and carbohydrate antigen 19-9 for colorectal cancer

(2015) Jian-Xia Yan et al.   Journal of Cancer Research and Therapeutics

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Ex vivo fucosylation of third-party human regulatory T cells enhances anti-graft-versus-host disease potency in vivo

(2014) S. Parmar et al.   BLOOD

Current concepts in the diagnosis and management of cytokine release syndrome

(2014) D. W. Lee et al.   BLOOD

Systemic inflammation promotes lung metastasis via E-selectin upregulation in mouse breast cancer model

(2014) Man Jiang et al.   CANCER BIOLOGY & THERAPY

Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?

(2014) Inge Marie Svane et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Enhancement of T cell recruitment and infiltration into tumours

(2014) C. Oelkrug et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Radiation-enhanced cell migration/invasion process: A review

(2014) Coralie Moncharmont et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

TIM-1 Glycoprotein Binds the Adhesion Receptor P-Selectin and Mediates T Cell Trafficking during Inflammation and Autoimmunity

(2014) Stefano Angiari et al.   IMMUNITY

Marked anti-tumor effects of CD8+CD62L+T cells from melanoma-bearing mice

(2014) Yunmei Liao et al.   IMMUNOLOGICAL INVESTIGATIONS

Stat6 Signaling Suppresses VLA-4 Expression by CD8+ T Cells and Limits Their Ability to Infiltrate Tumor Lesions In Vivo

(2014) K. Sasaki et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Dynamically Regulate Selectin Ligand Function during Multiple Challenge Contact Hypersensitivity

(2014) Latasha D. Abeynaike et al.   JOURNAL OF IMMUNOLOGY

IL-2: The First Effective Immunotherapy for Human Cancer

(2014) S. A. Rosenberg   JOURNAL OF IMMUNOLOGY

Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors

(2014) Gregory T Motz et al.   NATURE MEDICINE

A Potential Role for Immunotherapy in Thyroid Cancer by Enhancing NY-ESO-1 Cancer Antigen Expression

(2014) Viswanath Gunda et al.   THYROID

CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

(2014) H.-J. Kim et al.   Cancer Immunology Research

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

(2013) D Bedognetti et al.   BRITISH JOURNAL OF CANCER

Simultaneous Targeting of Tumor Antigens and the Tumor Vasculature Using T Lymphocyte Transfer Synergize to Induce Regression of Established Tumors in Mice

(2013) D. Chinnasamy et al.   CANCER RESEARCH

EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss

(2013) J. H. Sampson et al.   CLINICAL CANCER RESEARCH

The miRNAs in the pathgenesis of osteosarcoma 

(2013) Qingge Fu   Frontiers in Bioscience-Landmark

Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L

(2013) C. Marcela Díaz-Montero et al.   IMMUNOLOGIC RESEARCH

Cognate antigen directs CD8+ T cell migration to vascularized transplants

(2013) Jeffrey M. Walch et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

(2013) Bernd H. Zinselmeyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of Leukotriene B4 Receptor-1 on CD8+ T Cells Is Required for Their Migration into Tumors To Elicit Effective Antitumor Immunity

(2013) R. K. Sharma et al.   JOURNAL OF IMMUNOLOGY

Targeting T-cell migration in inflammatory bowel disease

(2013) J. Marsal et al.   JOURNAL OF INTERNAL MEDICINE

Genetically engineered T cells for the treatment of cancer

(2013) M. Essand et al.   JOURNAL OF INTERNAL MEDICINE

Anti-angiogenesis and metastasis: a tumour and stromal cell alliance

(2013) L. Moserle et al.   JOURNAL OF INTERNAL MEDICINE

Vascular E-Selectin Expression Correlates with CD8 Lymphocyte Infiltration and Improved Outcome in Merkel Cell Carcinoma

(2013) Olga K. Afanasiev et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Melanoma stem cells and metastasis: mimicking hematopoietic cell trafficking?

(2013) Nayoung Lee et al.   LABORATORY INVESTIGATION

Cytokine patterns in patients with cancer: a systematic review

(2013) Bodo E Lippitz   LANCET ONCOLOGY

Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes

(2013) Nandini Mondal et al.   Cell Adhesion & Migration

Tumor Endothelial Cells

(2013) A. C. Dudley   Cold Spring Harbor Perspectives in Medicine

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

Ways to Enhance Lymphocyte Trafficking into Tumors and Fitness of Tumor Infiltrating Lymphocytes

(2013) Matteo Bellone et al.   Frontiers in Oncology

CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy

(2012) Sivan Sapoznik et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Adoptive T-Cell Therapy Using Autologous Tumor-Infiltrating Lymphocytes for Metastatic Melanoma

(2012) Richard Wu et al.   CANCER JOURNAL

Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation

(2012) S. R. Barthel et al.   CANCER RESEARCH

NF- B Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells

(2012) R. Muthuswamy et al.   CANCER RESEARCH

Differential regulation and impact of fucosyltransferase VII and core 2 β1,6-N-acetyl-glycosaminyltransferase for generation of E-selectin and P-selectin ligands in murine CD4+T cells

(2012) Micha F. Schroeter et al.   IMMUNOLOGY

Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

(2012) Scott Wilkie et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Suppressing T cell motility induced by anti–CTLA-4 monotherapy improves antitumor effects

(2012) Maria Grazia Ruocco et al.   JOURNAL OF CLINICAL INVESTIGATION

Galectin-1 Triggers an Immunoregulatory Signature in Th Cells Functionally Defined by IL-10 Expression

(2012) F. Cedeno-Laurent et al.   JOURNAL OF IMMUNOLOGY

Tumor-specific CD4+ Melanoma Tumor-infiltrating Lymphocytes

(2012) Kevin M. Friedman et al.   JOURNAL OF IMMUNOTHERAPY

Lack of Functional Selectin Ligand Interactions Compromises Long Term Tumor Protection by CD8+ T Cells

(2012) Felicity C. Stark et al.   PLoS One

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

(2012) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

(2012) Jane L. Messina et al.   Scientific Reports

Suicide Gene Therapy to Increase the Safety of Chimeric Antigen Receptor-Redirected T Lymphocytes

(2012) Monica Casucci et al.   Journal of Cancer

High endothelial venules (HEVs) in human melanoma lesions

(2012) Ludovic Martinet et al.   OncoImmunology

Unique Ectopic Lymph Node-Like Structures Present in Human Primary Colorectal Carcinoma Are Identified by Immune Gene Array Profiling

(2011) Domenico Coppola et al.   AMERICAN JOURNAL OF PATHOLOGY

Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells

(2011) J. S. Merzaban et al.   BLOOD

VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth

(2011) Natasha Y. Frank et al.   CANCER RESEARCH

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

(2011) L. Martinet et al.   CANCER RESEARCH

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF- 

(2011) J. Lohr et al.   CLINICAL CANCER RESEARCH

The biology of CD44 and HCELL in hematopoiesis: the ‘step 2-bypass pathway’ and other emerging perspectives

(2011) Robert Sackstein   CURRENT OPINION IN HEMATOLOGY

Subsets of human CD4+ regulatory T cells express the peripheral homing receptor CXCR3

(2011) André Hoerning et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD44 and HCELL: Preventing hematogenous metastasis at step 1

(2011) Pieter P. Jacobs et al.   FEBS LETTERS

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

(2011) Catherine Larochelle et al.   FEBS LETTERS

Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes

(2011) Nadia Anikeeva et al.   IMMUNOLOGIC RESEARCH

Mechanisms regulating chemokine receptor activity

(2011) Laura D. Bennett et al.   IMMUNOLOGY

Cytotoxic T lymphocyte perforin and Fas ligand working in concert even when Fas ligand lytic action is still not detectable

(2011) David Hassin et al.   IMMUNOLOGY

CXCR3 ligands: redundant, collaborative and antagonistic functions

(2011) Joanna R Groom et al.   IMMUNOLOGY AND CELL BIOLOGY

Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions

(2011) Jeffrey C Nolz et al.   Immunotherapy

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire ofN- andO-Glycans without Direct Incorporation

(2011) Steven R. Barthel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells

(2011) Daniel T. Fisher et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolic Inhibition of Galectin-1-Binding Carbohydrates Accentuates Antitumor Immunity

(2011) Filiberto Cedeno-Laurent et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots

(2011) Ziv Shulman et al.   NATURE IMMUNOLOGY

The Shedding of CD62L (L-Selectin) Regulates the Acquisition of Lytic Activity in Human Tumor Reactive T Lymphocytes

(2011) Shicheng Yang et al.   PLoS One

Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells

(2011) S. P. Thankamony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

(2011) Sachie Hiratsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focus on Adoptive T Cell Transfer Trials in Melanoma

(2010) Liat Hershkovitz et al.   Clinical & Developmental Immunology

Transduction of Tumor-Specific T Cells with CXCR2 Chemokine Receptor Improves Migration to Tumor and Antitumor Immune Responses

(2010) W. Peng et al.   CLINICAL CANCER RESEARCH

T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes

(2010) Monika Raab et al.   IMMUNITY

Memory T-cell trafficking: new directions for busy commuters

(2010) Federica M. Marelli-Berg et al.   IMMUNOLOGY

Differential regulation of human and murine P-selectin expression and function in vivo

(2010) Zhenghui Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+T cell concentration determines their efficiency in killing cognate antigen–expressing syngeneic mammalian cells in vitro and in mouse tissues

(2010) Sadna Budhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of a Nascent Galectin-1 Chimeric Molecule for Studying the Role of Leukocyte Galectin-1 Ligands and Immune Disease Modulation

(2010) F. Cedeno-Laurent et al.   JOURNAL OF IMMUNOLOGY

Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants?

(2010) Amanda W. Lund et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The DNA demethylating agent 5-aza-2′-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells

(2010) Maika Almstedt et al.   LEUKEMIA RESEARCH

Embryonic trafficking of    T cells to skin is dependent on E/P selectin ligands and CCR4

(2010) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention

(2009) G. Gorfu et al.   CURRENT MOLECULAR MEDICINE

Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer

(2009) Bernhard Mlecnik et al.   GASTROENTEROLOGY

Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions

(2009) Jennifer K. Mulligan et al.   HUMAN IMMUNOLOGY

Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration

(2009) Robert Sackstein   IMMUNOLOGICAL REVIEWS

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

IL-4 Suppresses Very Late Antigen-4 Expression Which is Required for Therapeutic Th1 T-cell Trafficking Into Tumors

(2009) Kotaro Sasaki et al.   JOURNAL OF IMMUNOTHERAPY

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies

(2009) Marc Pellegrini et al.   NATURE MEDICINE

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

T Cell Trafficking in Allergic Asthma: The Ins and Outs

(2008) Benjamin D. Medoff et al.   Annual Review of Immunology

Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc

(2008) S. Yakubenia et al.   BLOOD

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

(2008) Jennifer A. Wargo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Equilibrium between Host and Cancer Caused by Effector T Cells Killing Tumor Stroma

(2008) B. Zhang et al.   CANCER RESEARCH

Interleukin-15/Interleukin-15R  Complexes Promote Destruction of Established Tumors by Reviving Tumor-Resident CD8+ T Cells

(2008) M. Epardaud et al.   CANCER RESEARCH

Homeostatic Proliferation Plus Regulatory T-Cell Depletion Promotes Potent Rejection of B16 Melanoma

(2008) J. Kline et al.   CLINICAL CANCER RESEARCH

IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit

(2008) Kotaro Sasaki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of β7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease

(2008) Maria Apostolaki et al.   GASTROENTEROLOGY

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

(2008) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

(2008) Rachael A. Clark et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sialyl lewisx antigen-expressing human CD4+ T and CD8+ T cells as initial immune responders in memory phenotype subsets

(2008) Yue Zhang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Orchestrating the orchestrators: chemokines in control of T cell traffic

(2008) Shannon K Bromley et al.   NATURE IMMUNOLOGY

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

(2008) Robert Sackstein et al.   NATURE MEDICINE

Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

(2008) Naomi N. Hunder et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance

(2008) M Campoli et al.   ONCOGENE

Mechanisms of leucocyte recruitment to the inflamed large intestine: redundancy in integrin and addressin usage

(2008) L. V. BELL et al.   PARASITE IMMUNOLOGY

T-cell recruitment to the intestinal mucosa

(2008) William W. Agace   TRENDS IN IMMUNOLOGY

The highway code of T cell trafficking

(2007) FM Marelli-Berg et al.   JOURNAL OF PATHOLOGY

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

(2007) Ronald J Buckanovich et al.   NATURE MEDICINE