Article
Cardiac & Cardiovascular Systems
Li Zhou, Xinhao Liu, Min Yan, Wei Zhao, Dan Luo, Jing Liu, Changwei Chen, Yue Ming, Fengjiang Zhang, Qian Li, Lei Du, Jin Liu
Summary: For patients undergoing on-pump cardiac operation, a postoperative nadir hemoglobin below 7.0 g/dL increases the risk of death, while below 9.0 g/dL increases the risk of composite adverse events.
ANNALS OF THORACIC SURGERY
(2021)
Article
Oncology
Michael C. Tjong, Danielle S. Bitterman, Kristen Brantley, Anju Nohria, Udo Hoffmann, Katelyn M. Atkins, Raymond H. Mak
Summary: A prediction model for major adverse cardiac events (MACE) after radiotherapy was developed in patients with locally advanced non-small cell lung cancer (LA-NSCLC). The study found that pre-existing coronary heart disease (CHD), hypertension, and the percentage of left anterior descending (LAD) coronary artery receiving >= 15 Gy (LADV15) were important factors in predicting MACE.
RADIOTHERAPY AND ONCOLOGY
(2022)
Article
Surgery
Timothy G. Gaulton, Hannah Wunsch, Lakisha J. Gaskins, Charles E. Leonard, Sean Hennessy, Michael Ashburn, Colleen Brensinger, Craig Newcomb, Duminda Wijeysundera, Brian T. Bateman, Jennifer Bethell, Mark D. Neuman
Summary: This study investigated the association between preoperative benzodiazepine and Z-drug use and adverse outcomes after surgery, finding that their use increased the odds of adverse postoperative events, particularly when coprescribed with opioids.
Article
Anesthesiology
Tumader Khouja, Jifang Zhou, Walid F. Gellad, Kannop Mitsantisuk, Colin C. Hubbard, Connie H. Yan, Lisa K. Sharp, Gregory S. Calip, Charlesnika T. Evans, Katie J. Suda
Summary: This study evaluates the adverse outcomes and persistent opioid use (POU) after opioid prescriptions by dentists, based on whether opioids were overprescribed or within recommendations. The findings demonstrate that dental prescribing of opioids was associated with adverse outcomes and POU, even when prescriptions were concordant with guidelines. Additional efforts are required to improve analgesic prescribing in dentistry, especially in groups at high risk of opioid-related adverse outcomes.
Article
Cardiac & Cardiovascular Systems
Dmytro Onishchenko, Daniel S. Rubin, James R. van Horne, R. Parker Ward, Ishanu Chattopadhyay
Summary: In this study, a novel artificial intelligence-based Cardiac Comorbidity Risk Score was introduced to predict major adverse cardiac events after elective hip and knee arthroplasty. By using patient electronic health records, this scoring system outperformed the traditional Revised Cardiac Risk Index across all studied subgroups.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Oncology
Michael M. Covell, Charles Bowers, Syed Faraz Kazim, Samantha Varela, Kavelin Rumalla, Meic H. Schmidt, Christian A. Bowers
Summary: By querying a large international surgical registry, we found that preoperative lab values have predictive accuracy for postoperative outcomes of metastatic brain tumor resection. Hypoalbuminemia, thrombocytopenia, and anemia were the strongest predictors of adverse postoperative outcomes.
Article
Cardiac & Cardiovascular Systems
Valery S. Effoe, Mark W. Mewissen, Tanvir K. Bajwa, Jayant Khitha, Louie Kostopoulos, Khawaja A. Ammar, Tonga K. Nfor
Summary: In adults undergoing femoropopliteal interventions, the use of atherectomy was associated with a reduction in major adverse limb events and a significantly decreased risk of major amputations compared to standard treatment.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Velimir S. Peric, Mladjan D. Golubovic, Milan Lazarevic, Tomislav L. Kostic, Dragana S. Stokanovic, Miodrag N. Dordevic, Vesna G. Marjanovic, Marija D. Stosic, Dragan J. Milic
Summary: The study aimed to evaluate the ability of risk prediction models and biomarkers in predicting MACE in elderly patients undergoing major elective vascular surgery, with NT-proBNP being an important predictive factor and the combination of GSCRI and NT-proBNP showing the best predictive performance.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Multidisciplinary Sciences
Xinju Zhao, Qingyu Niu, Liangying Gan, Fan Fan Hou, Xinling Liang, Zhaohui Ni, Yuqing Chen, Junhui Zhao, Brian Bieber, Bruce Robinson, Xiaonong Chen, Li Zuo
Summary: The number of hemodialysis patients in China is increasing rapidly, with most patients being older and primarily affected by chronic glomerulonephritis and diabetes. Some patients also have hepatitis B or C infections. The study provides insights into the demographic and clinical characteristics as well as treatment patterns of HD patients in China.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Mary J. Yeh, Kimberlee Gauvreau, Aimee K. Armstrong, Sarosh P. Batlivala, Ryan Callahan, Todd M. Gudausky, Michael R. Hainstock, Babar Hasan, George T. Nicholson, Michael L. O'Byrne, Shabana Shahanavaz, Sara Trucco, Jeffrey D. Zampi, Lisa Bergersen
Summary: This study aimed to describe the population of early postoperative catheterizations (EPOCs), evaluate procedural safety, compare EPOC patients with non-EPOC patients, and determine risk factors for poor outcomes. The results showed that EPOC was not associated with additional risk.
ANNALS OF THORACIC SURGERY
(2023)
Article
Ophthalmology
Marko M. Popovic, Matthew B. Schlenker, Deva Thiruchelvam, Donald A. Redelmeier
Summary: The safety of oral or topical carbonic anhydrase inhibitors in clinical care was analyzed in a population-based study. The risk of severe adverse reactions was low and similar between oral and topical forms of the medication. These findings support reconsidering the reluctance towards prescribing oral carbonic anhydrase inhibitors.
JAMA OPHTHALMOLOGY
(2022)
Article
Clinical Neurology
Olivier Q. Groot, Dennis Hundersmarck, Amanda Lans, Michiel E. R. Bongers, Aditya V. Karhade, Yue Zhang, Floris R. van Tol, Jorrit-Jan Verlaan, Jahan Mohebali, Joseph H. Schwab
Summary: This study aimed to assess the relationship between postoperative complications and VI in ALSS, finding a 2.7% incidence of complications in the VI group but no significant difference compared to the non-VI group. However, the VI group had significantly higher intraoperative blood loss and blood transfusion compared to the non-VI group.
Article
Surgery
Gustavo Romero-Velez, Jerry Dang, Juan S. Barajas-Gamboa, Terrence Lee-St John, Andrew T. Strong, Salvador Navarrete, Ricard Corcelles, John Rodriguez, Maan Fares, Matthew Kroh
Summary: This study evaluated and compared prediction models for MACE in bariatric surgery using traditional statistical methods and machine learning. The machine learning models showed good discriminant function and can assist clinicians in patient selection and identification of individuals at elevated risk of MACE after bariatric surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Cardiac & Cardiovascular Systems
Lorraine Sazgary, Christian Puelacher, Giovanna Lurati Buse, Noemi Glarner, Andreas Lampart, Daniel Bolliger, Luzius Steiner, Lorenz Guerke, Thomas Wolff, Edin Mujagic, Stefan Schaeren, Didier Lardinois, Jacqueline Espinola, Christoph Kindler, Angelika Hammerer-Lercher, Ivo Strebel, Karin Wildi, Reka Hidvegi, Johanna Gueckel, Christina Hollenstein, Tobias Breidthardt, Katharina Rentsch, Andreas Buser, Danielle M. Gualandro, Christian Mueller
Summary: MACE incidence after non-cardiac surgery is 15.2% at 30 days and 20.6% at 365 days for high-risk patients, with the risk remaining elevated for about 5 months post-surgery.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2021)
Article
Surgery
Eline Diender, Jenske J. M. Vermeulen, Ron Pisters, Paul M. van Schaik, Michel M. P. J. Reijnen, Suzanne Holewijn
Summary: MACE is a common complication during the first 5 years after elective EVAR. Predictors for MACE include ASA score, abdominal aortic diameter, history of atrial fibrillation, history of heart failure, valvular heart disease, and age. These factors could be helpful in optimizing postoperative long-term follow-up.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Nader Zamani, Sherene E. Sharath, Rocky C. Browder, Neal R. Barshes, Jonathan D. Braun, Joseph L. Mills, Panos Kougias, Houssam K. Younes
Summary: This study compared the treatment outcomes of long-segment SFA lesions, showing that DES had better primary-assisted and secondary patency compared to BMS and CS during long-term follow-up. However, CS was associated with a higher risk of acute limb ischemia when stent occlusion occurred.
ANNALS OF VASCULAR SURGERY
(2021)
Review
Oncology
Richard S. Whitlock, Kingsley Ebare, Lily S. Cheng, Douglas S. Fishman, Joseph L. Mills, HaiThuy N. Nguyen, Jed G. Nuchtern, Wenly Ruan, Valeria E. Smith, Kalyani A. Patel, Kevin E. Fisher, Sanjeev A. Vasudevan
Summary: This is the first reported case of pediatric pancreatic angiosarcoma with an activating KDR-internal tandem duplication. Literature on this disease process is very limited.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
(2022)
Article
Surgery
Jessica M. Mayor, Ourania Preventza, Katharine McGinigle, Joseph L. Mills, Miguel Montero-Baker, Ramyar Gilani, Zachary Pallister, Jayer Chung
Summary: Women have been historically under-represented in vascular surgery and cardiovascular medicine trials, and the rate and change in representation of women in trials of common vascular diseases over the last decade is not completely understood. Participants in trials for common vascular diseases are generally not representative of the actual disease population, with women consistently being underrepresented.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Jorge Miranda, Deepa Dongarwar, Hamisu M. Salihu, Miguel Montero-Baker, Ramyar Gilani, Zachary S. Pallister, Joseph L. Mills, Jayer Chung
Summary: The study found that rates of iatrogenic vascular injuries (IaVI's) increased among the top ten most frequently performed inpatient procedures in the United States from 2008 to 2015. Females, the elderly, and Hispanics were more likely to experience IaVI's. Overall, IaVI's independently increased the adjusted odds of mortality by 25%, with Blacks facing a 50% elevated risk compared to Non-Hispanic Whites.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Neal R. Barshes, Deeksha Bidare, Panos Kougias, Joseph L. Mills, Scott A. LeMaire
Summary: This study found that AAA screening has lower diagnostic rates among minority populations and suggests the need for various targeted strategies to address this disparity.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Karen Woo, Jeffrey J. Siracuse, Kyle Klingbeil, Larry W. Kraiss, Nicholas H. Osborne, Niten Singh, Tze-Woei Tan, Shipra Arya, Subhash Banerjee, Marc P. Bonaca, Thomas Brothers, Michael S. Conte, David L. Dawson, Young Erben, Benjamin M. Lerner, Judith C. Lin, Joseph L. Mills, Derek Mittleider, Deepak G. Nair, Leigh Ann O'Banion, Robert B. Patterson, Matthew J. Scheidt, Jessica P. Simons
Summary: The Society for Vascular Surgery created appropriate use criteria (AUC) for managing intermittent claudication using a validated method that combines evidence from medical literature with expert opinion. These criteria serve as a framework for shared decision-making between patients and clinicians. It is important to note that these criteria are not absolute and should be periodically reviewed for relevance.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Panos Kougias, Sherene E. Sharath, Nader Zamani, F. Charles Brunicardi, David H. Berger, Mark A. Wilson
Summary: Patients undergoing major operations within 8 weeks after a positive COVID-19 test have significantly higher postoperative 90-day mortality compared to controls without a COVID-19 diagnosis, regardless of presenting symptoms.
Article
Surgery
Jorge A. Miranda, Zachary Pallister, Sherene Sharath, Lucas Ferrer, Jayer Chung, Brian Lepow, Joseph L. Mills, Miguel Montero-Baker
Summary: This study reviewed the outcomes of venous arterialization (VA) in chronic limb-threatening ischemia (CLTI). The findings suggest that superficial and deep VA are feasible options for limb salvage in patients who cannot undergo conventional revascularization methods.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Deeksha Bidare, Sherene Sharath, Fred Cerise, Neal R. Barshes
Summary: Compared to privately insured patients, Medicaid patients are more likely to undergo leg amputations, which may be associated with factors such as infection, gangrene, type of care, hospital characteristics, and race. Focusing on preventative care and early outpatient referrals could help address this disparity.
SEMINARS IN VASCULAR SURGERY
(2023)
Article
Surgery
Mahmood Kabeil, Max Wohlauer, Mario D'Oria, Vipul Khetarpaul, Riley Gillette, Ethan Moore, Kathryn Colborn, Robert F. Cuff, Leigh Ann O'Banion, Issam Koleilat, Faisal Aziz, Nicolas J. Mouawad
Summary: The study found that during the COVID-19 pandemic, delays in carotid artery operations were primarily due to hospital policies, with most patients not deteriorating or requiring emergency surgery during the delay.
ANNALS OF VASCULAR SURGERY
(2023)
Article
Medicine, Research & Experimental
Panos Kougias, Zhibao Mi, Min Zhan, Jeffrey L. Carson, Hasan Dosluoglu, Peter Nelson, George A. Sarosi Jr, Shipra Arya, L. Erin Norman, Sherene Sharath, Alexandra Scrymgeour, Jade Ollison, Lawrence A. Calais, Kousick Biswas
Summary: The TOP Trial compares the effects of liberal and restrictive postoperative transfusion strategies on adverse outcomes in patients at high risk of postoperative cardiac events. This randomized controlled trial will be conducted in 15 Veterans Affairs hospitals with an expected enrollment of 1520 participants. The primary outcome is a composite endpoint of all-cause mortality, myocardial infarction, coronary revascularization, acute renal failure, or stroke occurring within 90 days after randomization.
CONTEMPORARY CLINICAL TRIALS
(2023)
Review
Endocrinology & Metabolism
Vivienne Chuter, Nicolaas Schaper, Joseph Mills, Robert Hinchliffe, David Russell, Nobuyoshi Azuma, Christian-Alexander Behrendt, Edward J. Boyko, Michael S. Conte, Misty Humphries, Lee Kirksey, Katharine C. McGinigle, Sigrid Nikol, Joakim Nordanstig, Vincent Rowe, Jos C. van den Berg, Maarit Venermo, Robert Fitridge
Summary: Early diagnosis and ongoing monitoring and treatment of peripheral artery disease (PAD) is crucial for reducing the risk of foot ulcer development, non-healing of wounds, infection, amputation, and cardiovascular complications in patients with diabetes. Various non-invasive bedside tests are available for diagnosing PAD, but the most accurate test and its reliability for ongoing monitoring are still uncertain. This systematic review aimed to determine the diagnostic accuracy of non-invasive bedside tests for identifying PAD and their reliability in adults with diabetes. The review included 40 studies on diagnostic accuracy and 7 studies on reliability. Ankle-brachial index (ABI) was the most investigated test. The review found that an ABI <0.9 increases the likelihood of disease, while an ABI within the normal range (≥0.90 and <1.3) does not exclude PAD. Toe-brachial index (TBI) and Doppler waveforms in the pedal arteries were also associated with PAD presence. Several bedside tests showed acceptable reliability, but the margin of error was wide. No single or combination of bedside tests demonstrated superior diagnostic accuracy for PAD in patients with diabetes. However, an ABI of 1.3, TBI <0.70, and absent or monophasic pedal Doppler waveforms can help identify the presence of disease.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Review
Endocrinology & Metabolism
Vivienne Chuter, Nicolaas Schaper, Robert Hinchliffe, Joseph Mills, Nobuyoshi Azuma, Christian-Alexander Behrendt, Edward J. Boyko, Michael S. Conte, Misty Humphries, Lee Kirksey, Katharine C. McGinigle, Sigrid Nikol, Joakim Nordanstig, Vincent Rowe, Russell David, Jos C. van den Berg, Maarit Venermo, Robert Fitridge
Summary: This systematic review aimed to determine the performance of non-invasive bedside tests for predicting the outcomes of DFU healing, minor amputation, and major amputation in people with diabetes and DFU or gangrene. The results showed that a toe pressure of ≥30 mmHg, TcPO2 of ≥25 mmHg, and skin perfusion pressure of ≥40 mmHg were associated with a moderate to large increase in the likelihood of DFU healing. However, there is limited research on the prognostic capacity of bedside testing for healing post-minor amputation or major amputation in people with DFU. Current evidence suggests that an ABI <0.4 may be associated with a large increase in the risk of major amputation.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Endocrinology & Metabolism
Robert Fitridge, Vivienne Chuter, Joseph Mills, Robert Hinchliffe, Nobuyoshi Azuma, Christian-Alexander Behrendt, Edward J. Boyko, Michael S. Conte, Misty Humphries, Lee Kirksey, Katharine C. Mcginigle, Sigrid Nikol, Joakim Nordanstig, Vincent Rowe, David Russell, Jos C. van den Berg, Maarit Venermo, Nicolaas Schaper
Summary: Diabetes-related foot complications, including peripheral artery disease (PAD), are increasing globally and causing major and minor amputations. The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines since 1999. This updated guideline, developed in collaboration with other vascular surgery societies, provides recommendations for diagnosing PAD, estimating healing and amputation outcomes, and treating PAD in individuals with diabetes mellitus and foot ulcers.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Dermatology
Hailey R. Donnelly, Erin D. Clarke, Clare E. Collins, Rebecca A. Collins, David G. Armstrong, Joseph L. Mills, Peta E. Tehan
Summary: The inaugural expert consensus and guidance for Nutrition Interventions in Adults with Diabetic Foot Ulcers (DFU) have provided important guidance for clinicians and revealed inadequacies in the dietary intake of individuals with DFU. Future guidelines should consider evidence-based recommendations and include all essential nutrients for wound healing in DFU.
INTERNATIONAL WOUND JOURNAL
(2023)