Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer

Quercetin-induced miR-200b-3p regulates the mode of self-renewing divisions in pancreatic cancer

(2017) Clifford C. Nwaeburu et al.   Molecular Cancer

Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis

(2017) E Agarwal et al.   ONCOGENE

MiR-650 represses high-risk non-metastatic colorectal cancer progression via inhibition of AKT2/GSK3β/E-cadherin pathway

(2017) Chunxian Zhou et al.   Oncotarget

Peroxiredoxin 2 is associated with colorectal cancer progression and poor survival of patients

(2017) LingLong Peng et al.   Oncotarget

Long noncoding RNA PVT1 promotes cervical cancer progression through epigenetically silencing miR-200b

(2016) Shaorong Zhang et al.   APMIS

MiR-200b promotes the cell proliferation and metastasis of cervical cancer by inhibiting FOXG1

(2016) Fei Zeng et al.   BIOMEDICINE & PHARMACOTHERAPY

A negative feedback loop between miR-200b and the nuclear factor-κB pathway via IKBKB/IKK-β in breast cancer cells

(2016) Hewen Wu et al.   FEBS Journal

BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis

(2016) Bobak Parang et al.   GUT

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family

(2016) Mohammed A. Suliman et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

miR-539 inhibits prostate cancer progression by directly targeting SPAG5

(2016) Hongtuan Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Peroxiredoxin II Is Essential for Maintaining Stemness by Redox Regulation in Liver Cancer Cells

(2016) Taeho Kwon et al.   STEM CELLS

Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer

(2016) Rong Wang et al.   Oncotarget

Examining plasma microRNA markers for colorectal cancer at different stages

(2016) Yan Sun et al.   Oncotarget

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62

(2015) W Wang et al.   ONCOGENE

The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers

(2015) S T Kundu et al.   ONCOGENE

microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs

(2015) Yi Pan et al.   RNA Biology

miR-612 negatively regulates colorectal cancer growth and metastasis by targeting AKT2

(2015) L Sheng et al.   Cell Death & Disease

The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer

(2015) Yuling Li et al.   Oncotarget

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma

(2015) Anna Trzeciecka et al.   Oncotarget

Peroxiredoxin 2 is involved in vasculogenic mimicry formation by targeting VEGFR2 activation in colorectal cancer

(2014) Shouru Zhang et al.   MEDICAL ONCOLOGY

Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

(2014) Maria Angelica Cortez et al.   MOLECULAR THERAPY

STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer

(2014) Z Zhang et al.   ONCOGENE

miR-200b Inhibits Prostate Cancer EMT, Growth and Metastasis

(2014) LaTanya V. Williams et al.   PLoS One

Peroxiredoxin 2 knockdown by RNA interference inhibits the growth of colorectal cancer cells by downregulating Wnt/β-catenin signaling

(2013) Weidong Lu et al.   CANCER LETTERS

Prognostic role of serum AZGP1, PEDF and PRDX2 in colorectal cancer patients

(2013) Dengbo Ji et al.   CARCINOGENESIS

miR-200b and miR-200c as Prognostic Factors and Mediators of Gastric Cancer Cell Progression

(2013) H. Tang et al.   CLINICAL CANCER RESEARCH

Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines

(2013) Jiu-Xu Bai et al.   ENDOCRINOLOGY

Perturbation of MicroRNA-370/Lin-28 homolog A/nuclear factor kappa B regulatory circuit contributes to the development of hepatocellular carcinoma

(2013) Wen-Ping Xu et al.   HEPATOLOGY

MicroRNA-200b Stimulates Tumour Growth in TGFBR2-Null Colorectal Cancers by Negatively Regulating p27/kip1

(2013) Yuxuan Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Peroxiredoxin 2 is upregulated in colorectal cancer and contributes to colorectal cancer cells’ survival by protecting cells from oxidative stress

(2013) Weidong Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways

(2013) X Li et al.   ONCOGENE

MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2

(2012) Li Liang et al.   GASTROENTEROLOGY

Polymorphisms of peroxiredoxin 1, 2 and 6 are not associated with esophageal cancer

(2012) Bo Zhang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

(2011) S. Agrawal-Singh et al.   BLOOD

MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1

(2011) L Sun et al.   ONCOGENE

miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1

(2010) J. D. Roybal et al.   MOLECULAR CANCER RESEARCH

Differential expression of peroxiredoxins in prostate cancer: Consistent upregulation of PRDX3 and PRDX4

(2010) Anamika Basu et al.   PROSTATE

Differential tissue-specific protein markers of vaginal carcinoma

(2009) K Hellman et al.   BRITISH JOURNAL OF CANCER

The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

(2009) Hugh K Arnold et al.   EMBO JOURNAL