Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry

Fully automated 5-plex fluorescent immunohistochemistry with tyramide signal amplification and same species antibodies

(2017) Wenjun Zhang et al.   LABORATORY INVESTIGATION

Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma

(2016) Elizabeth D Thompson et al.   GUT

Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trial

(2016) Kei Muro et al.   LANCET ONCOLOGY

Predictive biomarkers for checkpoint inhibitor-based immunotherapy

(2016) Geoffrey T Gibney et al.   LANCET ONCOLOGY

New immunotherapies targeting the PD-1 pathway

(2015) Jordan M. Chinai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

(2015) Anthony J. Sadler et al.   Nature Communications

The therapeutic promise of disrupting the PD-1/PD-L1 immune checkpoint in cancer: unleashing the CD8 T cell mediated anti-tumor activity results in significant, unprecedented clinical efficacy in various solid tumors

(2015) Emanuela Romano et al.   Journal for ImmunoTherapy of Cancer

Correlation between infiltration of FOXP3+ regulatory T cells and expression of B7-H1 in the tumor tissues of gastric cancer

(2014) Jingying Hou et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis

(2014) Edward C. Stack et al.   METHODS

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Tumor-Reactive CD8+ T Cells in Metastatic Gastrointestinal Cancer Refractory to Chemotherapy

(2013) S. Turcotte et al.   CLINICAL CANCER RESEARCH

Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer

(2013) M. Sznol et al.   CLINICAL CANCER RESEARCH

Guidelines and considerations for conducting experiments using tissue microarrays

(2013) Mohammad Ilyas et al.   HISTOPATHOLOGY

Increased PD-1 expression on CD4+ and CD8+ T cells is involved in immune evasion in gastric cancer

(2012) Hiroaki Saito et al.   JOURNAL OF SURGICAL ONCOLOGY

Expression of tumour-specific antigens underlies cancer immunoediting

(2012) Michel DuPage et al.   NATURE

Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection

(2010) Y.-Y. Wu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD4+CD25+CD127low/− regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression

(2009) Li-Song Shen et al.   CLINICAL IMMUNOLOGY

Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner

(2009) Xiang-Liang Yuan et al.   CLINICAL IMMUNOLOGY

Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer

(2008) H E Lee et al.   BRITISH JOURNAL OF CANCER

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY