Article
Mathematics
Yifan Gao, Lei Zhang, Chuanyue Wang, Xiaoyuan Zheng, Qianling Wang
Summary: This paper proposes a method for target assignment in three-dimensional scenarios based on evolutionary game theory, to enhance the operational efficiency and achieve maximum utility for multi-UAVs.
Article
Mathematics, Applied
Thomas A. Wettergren
Summary: The replicator dynamics of two-player evolutionary games with delays are examined. We investigate the stability in situations where the delays on cost contributions and benefit contributions may be different. It is shown that increasing one delay can lead to instability, but further increases in the delay can bring back stability, followed by more instability, and so on. This is in contrast to the case where costs and benefits share a common delay, where only a simple destabilization occurs. A Hopf bifurcation analysis is employed to analyze the phenomenon for a general version of evolutionary games and conditions for stabilizing and destabilizing phenomena are identified. Specific examples of snowdrift game and division of labor game are used to illustrate the results and numerical examples are provided to validate the claims.
APPLIED MATHEMATICS AND COMPUTATION
(2023)
Article
Computer Science, Information Systems
Ahmed A. Alabdel Abass, Narayan B. Mandayam, Zoran Gajic
Summary: Studied evolutionary game on graph with players' behavior affected by total number of players and number of each type of players.
Article
Mathematics, Applied
Md. Rajib Arefin, Jun Tanimoto
Summary: Human behaviors are strongly influenced by social norms, and this study shows that injunctive social norms can lead to bi-stability in evolutionary games. Different games exhibit different outcomes, with some showing the possibility of coexistence or a stable equilibrium.
APPLIED MATHEMATICS AND COMPUTATION
(2024)
Article
Physics, Multidisciplinary
Jianhong Ke, Ping-Ping Li, Zhenquan Lin
Summary: The study focuses on the evolutionary snowdrift game with an update rule of dissatisfaction-driven replicator on regular lattices. The equilibrium cooperation frequency fc against the cost-to-benefit ratio r has a step-like piecewise structure when dissatisfaction threshold K is small and transitions to a typical continuous form with increasing K. Analysis of stability and microscopic evolution helps interpret the emergence and disappearance of discontinuous transitions at critical values of r and snapshots of spatial strategy distribution patterns display the system's evolution. Numerical simulations show coexistence of cooperators and defectors for r < 2/3 and pure phase with only defectors for r > 3/4, with results consistent with those obtained by the master equation approach.
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
(2022)
Article
Engineering, Chemical
Chulwook Park
Summary: This paper proposes a mechanism for obtaining behavioral structures by simulating network-agent dynamics in an evolutionary public good game with available social learning. Relative payoffs and mutation play significant roles in the evolution of player strategies.
Article
Green & Sustainable Science & Technology
Yanwei You, Yuquan Chen, Yujun You, Qi Zhang, Qiang Cao
Summary: This paper aims to explore the potential of AI in the future of education using evolutionary game analysis. Strategies to improve the effectiveness of the education model in the AI era were identified, including positive supervision by schools and active involvement of students in AI technology. Schools can provide effective suggestions and practical guidelines to help students succeed academically and embrace future trends in AI education.
Article
Computer Science, Information Systems
Mengli Wang, Lipeng Song
Summary: This paper addresses the issue of spam and phishing emails, proposing an evolutionary game model to determine an effective defense strategy. The optimal number of protected users is influenced by factors such as email opening probability, attack cost, and attack loss. The study shows that the defense strategy is effective for maximizing defense resources in combating spam and phishing emails.
JOURNAL OF INFORMATION SECURITY AND APPLICATIONS
(2021)
Article
Physics, Fluids & Plasmas
Sayak Bhattacharjee, Vikash Kumar Dubey, Archan Mukhopadhyay, Sagar Chakraborty
Summary: Although nonconvergent evolution of population states in ecological and evolutionary contexts is well-known, there is a lack of insightful game-theoretic interpretations in evolutionary game theory literature. In this study, we utilize the concept of relative entropy from information theory to construct a game-theoretic interpretation for periodic orbits in deterministic discrete-time evolutionary game dynamics, specifically focusing on the two-player two-strategy case. We propose a consistent generalization of the evolutionarily stable strategy, called information stable orbit, which compares the total payoff obtained by an evolving mutant against itself. Additionally, we explore the connection between the information stable orbit and the dynamical stability of the corresponding periodic orbit.
Article
Mathematics, Interdisciplinary Applications
Tianyu Ren, Junjun Zheng
Summary: Altruistic sanctions play a crucial role in promoting cooperation in human society, and introducing a tolerance-based expulsion mechanism can significantly enhance cooperation, stabilize it under negative conditions, and determine the optimal threshold for implementation of expulsion.
CHAOS SOLITONS & FRACTALS
(2021)
Article
Mathematics, Applied
Qin Luo, Linjie Liu, Xiaojie Chen
Summary: This paper investigates the dynamics of cooperation in the N-person stag hunt game in various population structures. Utilizing the replicator equation, Markov process, and pair approximation approach, the study reveals the evolutionary characteristics of cooperation in the game across different scenarios.
PHYSICA D-NONLINEAR PHENOMENA
(2021)
Article
Chemistry, Multidisciplinary
N'guessan Yves-Roland Douha, Masahiro Sasabe, Yuzo Taenaka, Youki Kadobayashi
Summary: In the digital era, smart-home users need to prioritize cybersecurity education and training to protect their privacy and security. However, high training costs hinder widespread adoption. This study analyzes the costs and benefits of different cybersecurity investment strategies for smart-home users in the context of cyberattacks.
APPLIED SCIENCES-BASEL
(2023)
Article
Computer Science, Information Systems
Mohammad Hossein Ghasemian Koochaksaraei, Abolfazl Toroghi Haghighat, Mohammad Hossein Rezvani
Summary: The paper proposes a method to model the exchange of VM instances among CSPs using a combination of barter and evolutionary game theory. The proposed model does not require monetary exchange or separate contracts, and it leads to a 5% improvement in social welfare and a 3% reduction in the number of contracts.
CLUSTER COMPUTING-THE JOURNAL OF NETWORKS SOFTWARE TOOLS AND APPLICATIONS
(2023)
Article
Multidisciplinary Sciences
Christopher H. Lean, W. Ford Doolittle, Joseph P. Bielawski
Summary: Understanding community-level selection requires considering both community-level inheritance and community-level heritability, which are often conflated. Treating communities as interactors provides a more plausible and empirically supportable model for the role of ecological communities in evolution.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Physics, Multidisciplinary
Chaoqian Wang, Kangshuo Hui
Summary: A new type of group game called the involution game is proposed, where individuals compete for fixed resources by effort. Research shows that more abundant resources promote involution, while an increase in the relative utility of more effort aggravates involution. Increasing the cost of more effort may exacerbate involution in some cases, but ultimately leads to a disincentive to involution.
Article
Biochemical Research Methods
Gregory J. Kimmel, Philip Gerlee, Philipp M. Altrock
PLOS COMPUTATIONAL BIOLOGY
(2019)
Article
Oncology
Gregory J. Kimmel, Mark Dane, Laura M. Heiser, Philipp M. Altrock, Noemi Andor
Article
Multidisciplinary Sciences
Mehdi Damaghi, Jeffrey West, Mark Robertson-Tessi, Liping Xu, Meghan C. Ferrall-Fairbanks, Paul A. Stewart, Erez Persi, Brooke L. Fridley, Philipp M. Altrock, Robert A. Gatenby, Peter A. Sims, Alexander R. A. Anderson, Robert J. Gillies
Summary: The harsh microenvironment of ductal carcinoma in situ (DCIS) selects for a Warburg Effect (WE) phenotype through constitutive transcriptional reprogramming, with KLF4 potentially being an inducer of the WE phenotype. In vitro results were used to simulate DCIS phenotypic evolution using a mathematical model.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Ecology
Daria Miroshnychenko, Etienne Baratchart, Meghan C. Ferrall-Fairbanks, Robert Vander Velde, Mark A. Laurie, Marilyn M. Bui, Aik Choon Tan, Philipp M. Altrock, David Basanta, Andriy Marusyk
Summary: The study demonstrates that spontaneous fusions between cancer cells can lead to partial recombination, increasing heterogeneity and phenotypic plasticity of tumor cells, accelerating their ability to adapt to new selective pressures.
NATURE ECOLOGY & EVOLUTION
(2021)
Article
Biology
Gregory J. Kimmel, Frederick L. Locke, Philipp M. Altrock
Summary: CAR T cell therapy relies on engineered T cells expanding in vivo after chemotherapy-induced lymphodepletion. A mathematical model was developed to explain T cell-tumor cell interactions, showing that cure is a stochastic event influenced by patient variability. The model suggests optimizing tumor-killing rate and CAR T cells' carrying capacity to improve therapy outcomes.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Review
Oncology
Noemi Andor, Philipp M. Altrock, Navami Jain, Ana P. Gomes
Article
Oncology
Meghan C. Ferrall-Fairbanks, Nicholas H. Chakiryan, Boris I. Chobrutskiy, Youngchul Kim, Jamie K. Teer, Anders Berglund, James J. Mule, Michelle Fournier, Erin M. Siegel, Jasreman Dhillon, Seyed Shayan A. Falasiri, Juan F. Arturo, Esther N. Katende, George Blanck, Brandon J. Manley, Philipp M. Altrock
Correction
Biology
Gregory J. Kimmel, Frederick L. Locke, Philipp M. Altrock
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Biochemical Research Methods
Philip Gerlee, Philipp M. Altrock, Adam Malik, Cecilia Krona, Sven Nelander
Summary: This article studies the Allee effect in cancer using an individual-based model. The study finds that autocrine signaling plays a crucial role in the generation of the Allee effect, where low cell densities can lead to reduced or negative growth rate. The results of the model are consistent with experimental observations and have important implications for understanding and treating cancer dynamics.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Letter
Hematology
Guranda Chitadze, Anna Stengel, Cathrin John-Klaua, Julien Bruckmueller, Heiko Trautmann, Michaela Kotrova, Franziska Darzentas, Miriam Kelm, Karol Pal, Nikos Darzentas, Lorenz Bastian, Britta Kehden, Wiebke Wessels, Aeint-Steffen Stroeh, Hans -Heinrich Oberg, Philipp M. Altrock, Constance Baer, Manja Meggendorfer, Nicola Goekbuget, Claudia D. Baldus, Claudia Haferlach, Monika Brueggemann
Article
Biochemical Research Methods
Gregory J. Kimmel, Richard J. Beck, Xiaoqing Yu, Thomas Veith, Samuel Bakhoum, Philipp M. Altrock, Noemi Andor
Summary: Chromosome missegregations are common and can lead to drastic differences between daughter cells and parental cells. A mathematical model has been developed to account for cell-to-cell diversity caused by missegregations. The model can be used to understand selection and genotype-to-phenotype mapping, and has application in studying the upper limit of missegregation rate in cancer populations.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Hematology
Erin A. Dean, Gregory J. Kimmel, Matthew J. Frank, Ali Bukhari, Nasheed M. Hossain, Michael D. Jain, Saurabh Dahiya, David B. Miklos, Philipp M. Altrock, Frederick L. Locke
Summary: We investigated the relationship between total metabolic tumor volume (MTV) on positron emission tomography (PET) scans and circulating tumor DNA (ctDNA) in patients with relapsed/refractory large B-cell lymphoma receiving axicabtagene ciloleucel (axi-cel). Our results suggested that nonprogressing hypermetabolic lesions on 1-month PET represent ongoing treatment responses, and their composition may be elucidated by concurrently examining the ctDNA.
Article
Oncology
Meghan C. Ferrall-Fairbanks, Abhishek Dhawan, Brian Johnson, Hannah Newman, Virginia Volpe, Christopher Letson, Markus Ball, Anthony M. Hunter, Maria E. Balasis, Traci Kruer, Nana Adjoa Ben-Crentsil, Jodi L. Kroeger, Robert Balderas, Rami S. Komrokji, David A. Sallman, Jing Zhang, Rafael Bejar, Philipp M. Altrock, Eric Padron
Summary: Our study reveals the differentiation trajectories of CD34+ hematopoietic stem and progenitor cells (HSPC) in chronic myelomonocytic leukemia (CMML) and identifies the monocytic-biased trajectory as an adverse feature associated with poorer outcomes. We find that cytokine receptor diversity is elevated in GMP-like cells, which contributes to the monocytic-biased state. Hypomethylating agents and hematopoietic stress are found to affect the monocytic-biased state. Our findings suggest that deconvoluting HSPC compartments and exploring therapeutic strategies to mitigate the monocytic-biased differentiation trajectory should be further investigated in other myeloid neoplasms.
BLOOD CANCER DISCOVERY
(2022)
Article
Multidisciplinary Sciences
Brian Johnson, Philipp M. Altrock, Gregory J. Kimmel
Summary: Research shows that in public goods games, the traits of production and neighborhood size of individuals coevolve, leading to the emergence of a dimorphic population. Population size plays a crucial role in determining the final state of the population, with small populations potentially branching or experiencing extinction of subpopulations.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Biology
Gregory J. Kimmel, Philip Gerlee, Joel S. Brown, Philipp M. Altrock
COMMUNICATIONS BIOLOGY
(2019)