Article
Construction & Building Technology
Zhe Zeng, Bin Liu, Derun Zhang
Summary: It is known that asphalt concrete has three unit response functions: complex modulus, relaxation modulus, and creep compliance. This study systematically compares and evaluates three classical methods for interconverting these functions. The results show that all three methods can provide reasonable results with wide and appropriate relaxation/retardation time range. However, the windowing method is found to have fewer solving issues and is recommended for asphalt concrete determination.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Construction & Building Technology
Lei Xi, Rong Luo, Qiang Ma, Chongzhi Tu, Yasir Ibrahim Shah
Summary: This study developed an improved method to determine the continuous relaxation spectrum of asphalt materials, demonstrating compliance with LVE theory and physical causality. The generated relaxation spectrum was accurate enough to compare the storage modulus and loss modulus values recalculated by the relaxation spectrum with those predicted by master curve models, highlighting the limitations of the Kramers-Kronig relation for establishing the relaxation spectrum of asphalt materials. Additionally, the generated relaxation spectrum was utilized to construct the relaxation modulus of mixtures and to develop the stiffness modulus of binders, both consistent with LVE theory and physical causality.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
A. R. Dusane, P. Lenarda, M. Paggi
Summary: This study experimentally characterizes and computationally models the viscoelastic response of commercially available backsheet materials, proposing small-strain viscoelastic models based on Prony-series and Fractional Calculus. The models are validated with experimental data and show good predictability, aiding in the design and simulation of a more comprehensive digital-twin model of PV modules.
MECHANICS OF MATERIALS
(2023)
Article
Polymer Science
Jusuf Ibrulj, Ejub Dzaferovic, Murco Obucina, Manja Kitek Kuzman
Summary: This research aims to determine the relaxation and creep modulus of 3D printed materials through experiments and numerical analysis. The study considered the temperature effect on relaxation modulus and used the finite volume method and DMA analysis. The experimental and numerical results showed a good agreement.
Article
Polymer Science
Anna Stankiewicz
Summary: The goal of this paper is to study the applicability of the relaxation spectrum of the fractional Maxwell model (FMM) to the description of the relaxation spectra of polymers. Analytical formulas for the relaxation time and frequency spectra of the FMM model were derived, and the monotonicity and asymptotic properties of the spectra were analyzed. The existence of local extrema of the relaxation spectra was examined and a simple procedure for checking their existence or absence was developed. The applicability of the continuous-discrete spectrum of FMM to describe commonly used relaxation spectra in rheology was also investigated.
Article
Urology & Nephrology
Jianli Wang, Jiawei Chen, Xincheng Gao, Bing Li
Summary: This study aims to evaluate the viscoelastic properties of fresh porcine ureter and demonstrates the applicability of the QLV theory in describing its stress relaxation function. The eight constants of ureteral tissue are determined through data fitting with the model.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2022)
Article
Multidisciplinary Sciences
M. Gabriela Espinosa, Gaston A. Otarola, Jerry C. Hu, Kyriacos A. Athanasiou
Summary: This study utilized vibrometry as a rapid and non-contact method for dynamic mechanical characterization of knee cartilage, revealing significant differences among different cartilages and suggesting that meniscus may lack shock absorption abilities.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2021)
Article
Engineering, Mechanical
Marco Amabili, Prabakaran Balasubramanian, Giovanni Ferrari
Summary: This study explores the increase in damping with vibration amplitude and the increase in stiffness with vibration frequency in nonlinear vibrations of rectangular plates. A fractional linear solid model is applied to capture these phenomena and the frequency-dependent nonlinear damping. The results are compared with experimental data, showing good agreement in various aspects of the vibration response.
NONLINEAR DYNAMICS
(2021)
Article
Polymer Science
Anna Stankiewicz
Summary: The paper discusses the recovery of the relaxation spectrum of linear viscoelastic materials from discrete-time noise-corrupted measurements of relaxation modulus obtained in the stress relaxation test. A class of robust algorithms is proposed to approximate the continuous spectrum of relaxation frequencies, with a quadratic identification index adopted. Tikhonov regularization combined with generalized cross-validation is used to ensure the stability of the scheme, and the series expansions using different basis functions are studied as examples.
Article
Biotechnology & Applied Microbiology
Rosti Readioff, Brendan Geraghty, Yalda A. Kharaz, Ahmed Elsheikh, Eithne Comerford
Summary: This study qualitatively investigated the contribution of proteoglycans (PGs) to the biomechanical behavior of the canine cranial cruciate ligament (CCL). The results suggest that altering PGs content changes the microstructural organization and viscoelasticity of the CCLs, which may predispose to injury and lead to knee joint osteoarthritis.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Mechanics
Wei Cao, Andrew Lacroix, Y. Richard Kim
Summary: Asphalt concrete materials exhibit pressure dependence in response to mechanical loading, but the study showed that confining conditions have minimal impact on molecular processes during relaxation due to low aggregate mobility. The research developed a triaxial linear viscoelastic characterization framework to predict dynamic modulus with high accuracy, and found that pressure sensitivity is fully assigned to the equilibrium modulus.
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS
(2022)
Article
Engineering, Biomedical
Samantha Stewart, Wenquan Ou, Helim Aranda-Espinoza, Shaik O. Rahaman, Xiaoming He
Summary: Ovarian follicles develop in a regulated mechanical microenvironment, and disruptions to this microenvironment can cause infertility. The viscoelastic properties of ovarian tissue have not been extensively studied. This study characterizes the elastic and viscoelastic properties of ovarian tissue from both reproductive age groups of domestic cats and identifies possible connections between mechanical and compositional heterogeneities. These findings may have important implications for biomimetic follicle culture.
ACTA BIOMATERIALIA
(2023)
Article
Materials Science, Multidisciplinary
Valentina Balbi, Tom Shearer, William J. Parnell
Summary: This article discusses the decomposition of the tensorial relaxation function for isotropic and transversely isotropic modified quasi-linear viscoelastic models. It demonstrates how to formulate the constitutive equation using a convenient decomposition of the relaxation tensor into scalar components and tensorial bases. It also shows that the bases must be symmetrically additive, ensuring consistency with the elastic limit.
MATHEMATICS AND MECHANICS OF SOLIDS
(2023)
Article
Materials Science, Ceramics
Naoyuki Kitamura, Takahiko Hayashido, Nana Matsushita, Kohei Fukumi, Hiroaki Uchiyama, Hiromitsu Kozuka
Summary: The viscoelastic behavior of alkali and alkaline earth aluminophosphate glasses was studied, and it was found that there are differences in the activation energy of the relaxation modulus between different series. Dynamic viscoelasticity measurements showed a difference in the dissociation energies of weak and strong bonds at the glass transition temperature.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2022)
Article
Polymer Science
Jehyeok Choi, Kwang Soo Cho, Mi Kyung Kwon
Summary: The relaxation spectrum of unentangled polymer solution is derived using the self-similarity approach, but this method does not work for entangled polymeric fluids. This paper confirms the universality of the exponent in the polymer melt spectrum by employing a new regression algorithm.
Article
Engineering, Biomedical
Fei Fang, Roscoe T. H. Linstadt, Guy M. Genin, Kollbe Ahn, Stavros Thomopoulos
Summary: Current surgical techniques for repairing torn rotator cuff tendons do not result in mechanically competent tendon-to-bone attachments, leading to high failure rates. A biocompatible and high-strength chitosan bioadhesive is proposed to improve tendon-to-bone repair strength and promote healing.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Civil
Yuan Feng, Yu Chen, Yifei Yao, Xiaowei Li, Aili Zhang, Guy M. M. Genin
Summary: This study investigates the structural changes of brain tissue after injury and suggests that changes in the neuro-vasculature may alter the mechanical responses of brain tissue, predisposing individuals to subsequent injuries.
ENGINEERING STRUCTURES
(2022)
Article
Engineering, Environmental
Chao Guo, Jingjing Hu, Wenqiang Gao, Peipei Gao, Zhiyan Cao, Ning Liu, Xue Wang, Wenju Liu, Jianjun Zhao, Jingao Dong, Guy M. Genin, Li Hong Zhou
Summary: The trichomes of Arabidopsis thaliana and Chinese cabbage accumulate Cd2+ complexes more rapidly and to a higher concentration when mechanically stimulated, suggesting a mechanobiological pathway for enhancing heavy metal detoxification. This acceleration in Cd2+ storage requires signaling through trichomes, as seen in comparisons with gl1-1 mutants.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Multidisciplinary Sciences
Usama Ismail, Roger A. Rowe, John Cashin, Guy M. Genin, Mohamed A. Zayed
Summary: Deep vein thrombosis (DVT) is a serious condition that is difficult to treat. Current treatment options are limited in effectiveness. We developed a new thrombectomy device that uses a sequestered approach to improve the treatment of DVT. The device shows promise for treating high risk large-volume DVT.
SCIENTIFIC REPORTS
(2022)
Review
Chemistry, Multidisciplinary
Hui Zhang, Yufei Ma, Yijie Wang, Lin Niu, Rui Zou, Min Zhang, Hao Liu, Guy M. Genin, Ang Li, Feng Xu
Summary: This article reviews the soft-hard tissue interfaces found in the body and their application in bioinspired engineering materials. It also describes a range of manufacturing technologies related to interfacial tissue engineering, hydrogel bioadhesion, and healthcare and medical devices.
Article
Engineering, Biomedical
Yan Hu, Yuanbo Jia, Siwei Wang, Yufei Ma, Guoyou Huang, Tan Ding, Dayun Feng, Guy M. Genin, Zhao Wei, Feng Xu
Summary: Injectable hydrogels have the potential to promote healing of brain lesions, but current challenges arise from the mismatch between the hydrogel and the brain tissue. This study develops a self-healing hydrogel that mimics the composition, stiffness, and viscoelasticity of native brain tissue, and shows promising results in an in vivo mouse model of brain lesions.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Biomedical
Rohit Gupta, Prashant Gupta, Sean Wang, Artem Melnykov, Qisheng Jiang, Anushree Seth, Zheyu Wang, Jeremiah J. Morrissey, Ige George, Sumanth Gandra, Pratik Sinha, Gregory A. Storch, Bijal A. Parikh, Guy M. Genin, Srikanth Singamaneni
Summary: By conjugating fluorescent gold nanorods with antibodies, conventional lateral-flow assays can achieve ultrahigh sensitivity, with a 1,000-fold improvement compared to laboratory-based tests. Plasmonically enhanced LFAs, read out using a standard fluorescence scanner, demonstrated 30-fold improvements in dynamic range and detection limits over gold-standard enzyme-linked immunosorbent assays and showed high clinical sensitivity and specificity for SARS-CoV-2 antibodies and antigens. This enhanced performance can also be achieved using an inexpensive portable scanner for the detection of IL-6 and SARS-CoV-2 nucleocapsid protein. The use of plasmonically enhanced LFAs offers significant advantages in sensitivity, speed, dynamic range, ease of use, and cost, making them promising for point-of-care diagnostics.
NATURE BIOMEDICAL ENGINEERING
(2023)
Editorial Material
Engineering, Biomedical
Derrick Dean, Amrinder S. Nain, Guy M. Genin
ACTA BIOMATERIALIA
(2023)
Review
Pharmacology & Pharmacy
Delaram Shakiba, Guy M. Genin, Silviya P. Zustiak
Summary: Mechanical forces play a central role in the interaction between cancer treatments and cells/tissues. In addition to electrostatic forces, mechanical factors also affect drug or immune cell targeting and therapeutic efficacy. This review explores the impact of mechanobiology on drug and immunotherapy resistance and responsiveness, as well as the use of in vitro systems for discovering these effects.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Editorial Material
Pharmacology & Pharmacy
Feng Xu, Hui Guo, Silviya P. Zustiak, Guy M. Genin
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Editorial Material
Multidisciplinary Sciences
Farid Alisafaei, Hamidreza Moheimani, Elliot L. Elson, Guy M. Genin
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Multidisciplinary Sciences
Ethan D. Hoppe, Victor Birman, Iden Kurtaliaj, C. Matt Guilliams, Barbara G. Pickard, Stavros Thomopoulos, Guy M. Genin
Summary: Studying the hooks of Harpagonella palmeri, researchers found strategies used by the plant to distribute loads, which could potentially double repair strength in surgical reattachment of tendon to bone compared to uniform suture distribution.
PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Zhiqiang Meng, Hujie Yan, Mingchao Liu, Wenkai Qin, Guy M. Genin, Chang Qing Chen
Summary: Information processing using material's own properties has gained increasing interest. A mechanical metamaterial system is demonstrated for material-based encoding and storage of data through programmed reconfigurations of the metamaterial's structured building blocks.
Article
Materials Science, Biomaterials
Eesha Khare, Xiangjun Peng, Zaira Martin-Moldes, Guy M. Genin, David L. Kaplan, Markus J. Buehler
Summary: Model verification is critical for scientific accountability, transparency, and learning. In this study, a model verification approach was applied to a molecular dynamics simulation, successfully replicating the key findings of the original model and gaining new insights. Improvements in model validation processes, particularly through enhanced documentation methods, were discussed. This protocol for model verification can be further applied to validate other simulations.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Xiangjun Peng, Yuxuan Huang, Guy M. Genin
Summary: Cells transmit mechanical signals through the extracellular matrix (ECM) and the pericellular matrix (PCM), but the presence of PCM weakens the transmission. However, elongation or contraction of cells can compensate for this effect and enable long-range force transmission. These findings are relevant to mechanical signaling in development, wound healing, and fibrosis.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2023)
Article
Engineering, Biomedical
Xinyao Zhu, Yifan Liu, Jing Ye, Wei Xu, Xuexia Zhao, Tianyan Liu
Summary: This study reveals the adverse effect of acid on dentin in terms of degradation of its fracture toughness. The peritubular dentin plays a significant role in enhancing the dentin's fracture resistance capability. The findings highlight the importance of structural integrity for dentin.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Priya Ranganathan, Vijayakumari Sugumaran, Bargavi Purushothaman, Ajay Rakkesh Rajendran, Balakumar Subramanian
Summary: The study aims to design and fabricate an ultra-easier multi-functional biomedical polymeric scaffold loaded with unique equimolar Ca:P phasic bioactive glass material. The results showed that the G:BG (1:2) ratio is the more appropriate composition for enhanced bio-mineralization and higher surface area. The scaffold can induce mitogenesis in osteoblast cells for hard tissue regeneration and rapid collagen secretion in fibroblast cells for soft tissue regeneration.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Ziad Guerfi, Oum keltoum Kribaa, Hanane Djouama
Summary: Hydroxyapatite, a biocompatible and bioactive ceramic material, has been widely studied in fields such as orthopedics and plastic surgery. The use of computational tools, especially density functional theory, has become increasingly important in research. In this study, Hydroxyapatite was synthesized using the double decomposition method and quantum mechanical computations were performed using density functional theory. The experimental and computational results confirmed the successful synthesis of Hydroxyapatite and showed good agreement in spectroscopic characterizations.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Sally AbdulHussain Kadhum, Nassier A. Nassir
Summary: In this research, porous composites were successfully prepared and reinforced for bone scaffold applications. The functional groups, pore structure, and composition distribution of the materials were characterized using techniques such as FTIR, Atomic Force Microscopy (AFM), and Scanning Electron Microscopy (SEM).
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Veronika Geiger, Felicitas Mayinger, Moritz Hoffmann, Marcel Reymus, Bogna Stawarczyk
Summary: The study investigated the mechanical properties of four additively manufactured denture base resins in different measurement environments, and found that the measurement environment impacts the strength and fracture toughness of the materials.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Junxiao Wang, Amatjan Sawut, Rena Simayi, Huijun Song, Xueying Jiao
Summary: The development of cost-effective and eco-friendly conductive hydrogels with excellent mechanical properties, self-healing capabilities, and non-toxicity is of great significance in the field of biosensors.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Yijun Zhou, Lisa Ho, Ayan Samanta, Philip Procter, Cecilia Persson
Summary: In this study, soft, non-setting biomaterials based on Hyalectin gels and different morphological parameters of hydroxyapatite (HA) particles were evaluated as potential augmentation materials for orthopaedic implant fixation. The results showed that constructs reinforced with irregularly shaped nano-HA particles and spherically shaped micro-HA particles had significantly higher pull-out force compared to the control group.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Mehdi Jahandardoost, Donald Ricci, Abbas S. Milani, Mohsen Jahandardoost, Dana Grecov
Summary: Tubular flow diverters are important for treating cerebral aneurysms. A new design called VR-eCLIPs has been developed to cover the neck of challenging bifurcation aneurysms. A finite element model has been used to simulate the implantation processes of VR-eCLIPs and assess potential plastic deformation.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Marek Traczynski, Adam Patalas, Katarzyna Roslan, Marcin Suszynski, Rafa l Talar
Summary: This article evaluates the forces acting on intravenous needles during insertion into the skin and selects the most suitable model for future research. The experimental results show that needle size, insertion angle, and insertion speed have an influence on the measured force values.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Chester Jar, Andrew Archibald, Monica Gibson, Lindsey Westover
Summary: This study evaluates the ASIST technique for assessing the stability of dental implants. The results show that the ASIST technique can reliably measure the interfacial stiffness of dental implants, which is not significantly influenced by different abutment types. This method may provide an improved non-invasive way to measure the stability of dental implants.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Ali Kamali, Kaveh Laksari
Summary: In this paper, a UNet-based neural network model (El-UNet) is developed to infer the spatial distributions of mechanical parameters. The El-UNet shows superior performance in terms of accuracy and computational cost compared to other neural network models. A self-adaptive spatial loss weighting approach is proposed, which achieves the most accurate reconstructions in equal computation times.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Chunyan Yu, Yanju Lu, Jinhui Pang, Lu Li
Summary: In this study, a safe and effective hemostatic composite sponge was developed by combining chitosan and hydroxypropylmethylcellulose (HPMC). The sponge exhibited excellent flexibility and rapid hemostatic ability in vitro. In vivo assessments showed that the sponge had the shortest clotting time and minimal blood loss.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Zhongliang Yu, Lin Yu, Junjie Liu
Summary: The study proposes incorporating functionally graded tablets into nacreous composites to enhance both stiffness and damping properties. Analytical formulae and numerical experiments demonstrate the effectiveness of this design, surpassing existing homogeneous composites in performance.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Marc Graham, Sandra Klinge
Summary: This study investigates the macroscopic diffusion behavior of heterogeneous gels using a homogenization method in a finite element framework. Two materials, calcifying PDMA and PAAm, were studied, and the results show that the diffusivity of PDMA has a strong nonlinear dependence on the solute molecule radius.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Abdur-Rasheed Alao
Summary: This study aimed to find the optimal sandblasting parameters for roughening YTZP surfaces. Through experimental and statistical analysis, the best setting was found to be IA = 45 degrees, AP = 110 μm, ST = 20 s, and P = 400 kPa, which resulted in the maximum surface roughness, phase transformation, and shear bond strength.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)