Analysis of Monoclonal Antibodies in Human Serum as a Model for Clinical Monoclonal Gammopathy by Use of 21 Tesla FT-ICR Top-Down and Middle-Down MS/MS

Rapid and improved characterization of therapeutic antibodies and antibody related products using IdeS digestion and subunit analysis

(2016) Jonathan Sjögren et al.   ANALYST

Using Mass Spectrometry to Quantify Rituximab and Perform Individualized Immunoglobulin Phenotyping in ANCA-Associated Vasculitis

(2016) John R. Mills et al.   ANALYTICAL CHEMISTRY

Characterization of Therapeutic Monoclonal Antibodies at the Subunit-Level using Middle-Down 193 nm Ultraviolet Photodissociation

(2016) Victoria C. Cotham et al.   ANALYTICAL CHEMISTRY

Comprehensive Assessment of M-Proteins Using Nanobody Enrichment Coupled to MALDI-TOF Mass Spectrometry

(2016) J. R. Mills et al.   CLINICAL CHEMISTRY

Screening Method for M-Proteins in Serum Using Nanobody Enrichment Coupled to MALDI-TOF Mass Spectrometry

(2016) M. C. Kohlhagen et al.   CLINICAL CHEMISTRY

Laboratory testing in monoclonal gammopathy of renal significance (MGRS)

(2016) Nelson Leung et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Monitoring free light chains in serum using mass spectrometry

(2016) David R. Barnidge et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Harnessing Fc receptor biology in the design of therapeutic antibodies

(2016) Peter Sondermann et al.   CURRENT OPINION IN IMMUNOLOGY

Diagnosis, risk stratification and management of monoclonal gammopathy of undetermined significance and smoldering multiple myeloma

(2016) N. W. C. J. van de Donk et al.   International Journal of Laboratory Hematology

Characterization of Drug-Product-Related Impurities and Variants of a Therapeutic Monoclonal Antibody by Higher Energy C-Trap Dissociation Mass Spectrometry

(2015) Deyun Wang et al.   ANALYTICAL CHEMISTRY

Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis

(2015) Yongle Pang et al.   ANALYTICAL CHEMISTRY

Monitoring oligoclonal immunoglobulins in cerebral spinal fluid using microLC-ESI-Q-TOF mass spectrometry

(2015) David R. Barnidge et al.   JOURNAL OF NEUROIMMUNOLOGY

21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis

(2015) Christopher L. Hendrickson et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Detecting monoclonal immunoglobulins in human serum using mass spectrometry

(2015) John R. Mills et al.   METHODS

Analysis of Monoclonal Antibody Sequence and Post-translational Modifications by Time-controlled Proteolysis and Tandem Mass Spectrometry

(2015) Lichao Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

ProSight Lite: Graphical software to analyze top-down mass spectrometry data

(2015) Ryan T. Fellers et al.   PROTEOMICS

Using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to detect monoclonal immunoglobulin light chains in serum and urine

(2015) David R. Barnidge et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Full Antibody Primary Structure and Microvariant Characterization in a Single Injection Using Transient Isotachophoresis and Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry

(2014) Rabah Gahoual et al.   ANALYTICAL CHEMISTRY

Advantages of Extended Bottom-Up Proteomics Using Sap9 for Analysis of Monoclonal Antibodies

(2014) Kristina Srzentić et al.   ANALYTICAL CHEMISTRY

Middle-Down Analysis of Monoclonal Antibodies with Electron Transfer Dissociation Orbitrap Fourier Transform Mass Spectrometry

(2014) Luca Fornelli et al.   ANALYTICAL CHEMISTRY

Antibody–drug conjugates—A new wave of cancer drugs

(2014) Hervé Bouchard et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Detecting monoclonal light chains in urine: microLC-ESI-Q-TOF mass spectrometry compared to immunofixation electrophoresis

(2014) Chad M. Botz et al.   BRITISH JOURNAL OF HAEMATOLOGY

Using Mass Spectrometry to Monitor Monoclonal Immunoglobulins in Patients with a Monoclonal Gammopathy

(2014) David R. Barnidge et al.   JOURNAL OF PROTEOME RESEARCH

Phenotyping Polyclonal Kappa and Lambda Light Chain Molecular Mass Distributions in Patient Serum Using Mass Spectrometry

(2014) David R. Barnidge et al.   JOURNAL OF PROTEOME RESEARCH

A new tool for monoclonal antibody analysis

(2014) Yan An et al.   mAbs

The therapeutic monoclonal antibody market

(2014) Dawn M Ecker et al.   mAbs

An integrated top-down and bottom-up proteomic approach to characterize the antigen-binding fragment of antibodies

(2014) Lennard Dekker et al.   PROTEOMICS

Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

(2013) Yuan Mao et al.   ANALYTICAL CHEMISTRY

Characterization of immunoglobulin by mass spectrometry with applications for the clinical laboratory

(2013) David Murray et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Characterization of Therapeutic Antibodies and Related Products

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma: A Review of the Current Understanding of Epidemiology, Biology, Risk Stratification, and Management of Myeloma Precursor Disease

(2012) A. Agarwal et al.   CLINICAL CANCER RESEARCH

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

(2012) Luca Fornelli et al.   MOLECULAR & CELLULAR PROTEOMICS

Probing deamidation in therapeutic immunoglobulin gamma (IgG1) by ‘bottom-up’ mass spectrometry with electron transfer dissociation

(2010) Raju Mukherjee et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

(2009) Pavel V. Bondarenko et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mass spectrometry for structural characterization of therapeutic antibodies

(2008) Zhongqi Zhang et al.   MASS SPECTROMETRY REVIEWS