Article
Multidisciplinary Sciences
Jinqiao Dong, Lingmei Liu, Chunxia Tan, Qisong Xu, Jiachen Zhang, Zhiwei Qiao, Dandan Chu, Yan Liu, Qun Zhang, Jianwen Jiang, Yu Han, Anthony P. Davis, Yong Cui
Summary: Researchers showed that crystals composed of discrete supramolecular coordination complexes can be exfoliated by sonication to produce free-standing monolayers. These monolayers have complex chiral surfaces and good crystallinity, and the intermolecular interactions sustaining them are purely due to apolar interactions. This unique material exhibits enhanced selectivity towards carbohydrate recognition.
Article
Chemistry, Physical
Chu-Wei Hsu, Takumi Ideta, Keisuke Awaya, Masayuki Tsushida, Tetsuya Sato, Kei-ichi Yanagisawa, Koji Kimoto, Kazuto Hatakeyama, Michio Koinuma, Shintaro Ida
Summary: The study successfully prepared oxynitride 2D crystals with triple perovskite units through the delamination of chemically stable layered oxynitrides, showing photocatalytic activity and the creation of oxynitride 2D crystal film.
CHEMISTRY OF MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Junjie Xu, Wei Li, Biao Zhang, Liang Zha, Wei Hao, Shixin Hu, Jinbo Yang, ShuZhou Li, Song Gao, Yanglong Hou
Summary: The study has successfully prepared free-standing 2D nvdWs hexagonal FeSe with a thickness of only 2.9 nm, demonstrating unique magnetic and semiconducting properties. Temperature variation leads to magnetic transitions, showing great potential for applications.
Article
Chemistry, Multidisciplinary
Veronica Montes-Garcia, Paolo Samori
Summary: This article summarizes the recent research progress on Janus 2D materials, focusing on the unique properties and potential applications brought about by decorating both sides of the surfaces.
Article
Chemistry, Multidisciplinary
Wuqian Guo, Haojie Xu, Yu Ma, Yi Liu, Beibei Wang, Liwei Tang, Lina Hua, Junhua Luo, Zhihua Sun
Summary: This article introduces a new type of semiconductor material with ferroelectric properties, which has high polarization and superior semiconductor performance, and has potential applications in self-driven polarized light detection and other fields.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Xianghui Zhang, Andre Beyer
Summary: This review summarizes recent progress in the mechanical characterization of free-standing 2D materials like graphene and explores their applications in mechanical devices. It is expected that there will be a continuous growth in interest and more systematic experimental work on the mechanics of such ultrathin nanomaterials.
Article
Materials Science, Multidisciplinary
Tumesh Kumar Sahu, Saroj Pratap Sahu, K. P. S. S. Hembram, Jae-Kap Lee, Vasudevanpillai Biju, Prashant Kumar
Summary: Two-dimensional gallium nitride (2D GaN) is a material with a large direct bandgap, high melting point, and large Young's modulus, making it suitable for miniaturized electronic gadgets. In this study, we successfully synthesized free-standing 2D GaN atomic sheets using sonochemical exfoliation and the modified Hummers method. The exfoliated sheets exhibited good chemical phase purity and stability, and showed potential applications in optoelectronics, spintronics, and sensors.
NPG ASIA MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Runfang Fu, Qianqian Shi, Zijun Yong, James C. Griffith, Lim Wei Yap, Wenlong Cheng
Summary: The newly designed Janus plasmene nanosheets achieved efficient photochemical conversion on a flexible polymer substrate, with the potential for adjusting catalytic efficiency by modifying palladium thickness or building block types. A 3D printed artificial tree could continuously convert 30 mL of chemicals in 45 minutes.
MATERIALS HORIZONS
(2021)
Article
Chemistry, Multidisciplinary
Eisuke Yamamoto, Kosuke Fujihara, Yuma Takezaki, Kentaro Ito, Yue Shi, Makoto Kobayashi, Minoru Osada
Summary: Recent progress in 2D materials has led to the exploration of molecularly thin amorphous materials with unique properties and structures. However, the synthesis of molecularly thin amorphous silica remains a challenge, and the existence of free-standing silica nanosheets is still uncertain. In this study, a new chemical protocol is introduced, where solid-state surfactant lamellae with ordered alkyl-chain arrangements act as templates to guide the formation of free-standing amorphous silica nanosheets. Sonication of the lamellar hybrids results in the exfoliation of monolayer amorphous silica nanosheets with a thickness of 0.9 nm. These nanosheets also exhibit high colloidal stability, enabling atomic layer engineering of silica nanocoatings and dielectric nanofilms. This approach offers new insights into the properties and applications of silica.
Article
Chemistry, Multidisciplinary
Shine K. Albert, Sunghee Lee, Prasannavenkatesh Durai, Xiaole Hu, Byeongmoon Jeong, Keunwan Park, So-Jung Park
Summary: The study demonstrates the fabrication of Janus nanosheets from molecular building blocks composed of DNA and peptides, and reveals the formation of nanosheets with distinct DNA and peptide faces. The surprisingly level of structural control is attributed to the exclusive parallel beta-sheet formation of phenylalanine-rich peptides. Furthermore, the predictable and designable peptide interaction is shown to be a promising tool for creating Janus nanostructures with regio-selective and sequence-specific molecular recognition properties.
Article
Materials Science, Multidisciplinary
Raul Zazpe, Hanna Sopha, Jaroslav Charvot, Richard Krumpolec, Jhonatan Rodriguez-Pereira, Jan Michalicka, Jan Mistrik, Dominik Baca, Martin Motola, Filip Bures, Jan M. Macak
Summary: The synthesis of MoTe2 nanosheets by ALD was demonstrated for the first time, showing tight control over thickness and composition. The out-of-plane oriented MoTe2 nanosheets, combined with optimized catalytic edges and fast electron transfer properties, exhibited enhanced catalytic performance for both organic pollutant degradation and hydrogen evolution reactions.
APPLIED MATERIALS TODAY
(2021)
Article
Chemistry, Multidisciplinary
Marc Julian Kloberg, Haoyang Yu, Elisabeth Gross, Felix Eckmann, Tassilo M. F. Restle, Thomas F. Faessler, Jonathan G. C. Veinot, Bernhard Rieger
Summary: The study introduces a novel synthesis method for surface-anisotropic silicon quantum dots on a 2D silicon nanosheet, showing potential in self-assembly, microelectronics, and biology. By exposing only one side of the QDs and introducing two different functional groups, the unique optoelectronic properties of the SiQDs are retained. The anisotropic morphology is confirmed through the aggregation behavior of amphiphilic Janus SiQDs at the water-hexane interface, demonstrating the versatility of these nanoparticles.
ADVANCED MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Mingjun Bai, Junyi Li, Xiaohe Liu, Takayoshi Sasaki, Renzhi Ma
Summary: Self-standing membranes composed of luminescent rare-earth hydroxide and semiconducting oxide nanosheets were fabricated, exhibiting significantly enhanced emission intensity, color purity, and lifetime. The integrated membranes showed tunable color under different excitations. Strong and stable cathodoluminescence was observed under continuous cathode-ray radiation.
ADVANCED OPTICAL MATERIALS
(2022)
Review
Biochemistry & Molecular Biology
Artemii S. Ivanov, Lyubov Pershina, Konstantin G. Nikolaev, Ekaterina Skorb
Summary: Polyelectrolytes play a crucial role in the development of new materials, allowing for the creation of new properties of materials and surfaces. They are utilized in layer-by-layer deposition, free-standing films, and hydrogels, with applications in giving surfaces new properties, designing membranes and sensors, and showcasing applicability in electrical and materials science. Exciting new technologies have been developed with polyelectrolytes over the last five years.
MACROMOLECULAR BIOSCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Lei Xie, Shan Zhou, Xiaofeng Li, Xin Zhang, Hui Zeng, Yanjun He, Jie Zeng, Kang Liang, Lei Jiang, Biao Kong
Summary: Functional nanosheets and heterostructure membrane devices are prepared through a simple interfacial assembly strategy. This monolayered interfacial assembly approach can open up new avenues for the synthesis of functional porous low-dimensional nanomaterials and membrane devices, and expand the palette of materials selection for many applications.
Article
Chemistry, Multidisciplinary
Rujie Sun, Xin Song, Kun Zhou, Yuyang Zuo, Richard Wang, Omar Rifaie-Graham, David J. Peeler, Ruoxiao Xie, Yixuan Leng, Hongya Geng, Giulia Brachi, Yun Ma, Yutong Liu, Lorna Barron, Molly M. Stevens
Summary: This study presents a versatile platform for fabricating fillable microrobots using microfluidic loading and dip sealing (MLDS), which allows for encapsulating different types of cargoes within hollow microrobots and protecting the cargo integrity. The technique is supported by high-resolution 3D printing and an integrated microfluidic loading system, enabling a highly precise loading process and improved cargo loading capacity. The MLDS platform offers new opportunities for targeted drug delivery, environmental sensing, and chemically powered micromotor applications.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Lizebona August Ambattu, Callum Knight, Keng-hui Lin, Amy Gelmi, Leslie Y. Yeo
Summary: This study investigates the effects of short-duration mechanostimulation on endothelial junction stability and barrier capacity. The study found that the integrity of the endothelial barrier can not only recover but also enhance considerably after transient disruption, thanks to the role of calcium and cAMP signaling. Such enhancement in barrier capacity is useful for developing in vitro models that resemble in vivo conditions.
Review
Chemistry, Multidisciplinary
Arman Ahnood, Andre Chambers, Amy Gelmi, Ken-Tye Yong, Omid Kavehei
Summary: The advent of electronic technology for neural interfacing in the past 50 years has transformed medicine and biology. Devices like deep brain stimulators and cochlear implants have revolutionized the treatment of previously untreatable conditions. Semiconducting electrodes have advanced neural interfacing technologies, enabling high precision sensing and stimulation in electrical, biochemical, and optical domains. This emerging class of electrodes offers new opportunities for research and treatment.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Neurosciences
Stephanie A. Maynard, Jonas Ranft, Antoine Triller
Summary: The molecular composition of presynaptic and postsynaptic neuronal terminals is dynamic, and long-term stabilizations in postsynaptic responses are necessary for synaptic development and long-term plasticity. Single-particle tracking and statistical thermodynamics provide methods and frameworks for quantitative descriptions of molecular fluctuations, turnover, stability, and plasticity in synapses. The molecular organization of the synapse is both highly organized and dynamic, and single-particle tracking technologies have improved our understanding of the mechanisms regulating postsynaptic receptor dynamics.
NATURE REVIEWS NEUROSCIENCE
(2023)
Review
Chemistry, Multidisciplinary
Alvaro Fernandez-Galiana, Olga Bibikova, Simon Vilms Pedersen, Molly M. Stevens
Summary: This paper comprehensively introduces the theoretical and practical background of Raman spectroscopy and its advanced variants. It highlights the various aspects of material characterization that Raman scattering can reveal and emphasizes its potential in biomedical material design and development. Additionally, practical recommendations on the integration of Raman techniques into the experimental laboratory toolbox are provided.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Adam Creamer, Alessandra Lo Fiego, Alice Agliano, Lino Prados-Martin, Hakon Hogset, Adrian Najer, Daniel. A. A. Richards, Jonathan. P. P. Wojciechowski, James E. J. Foote, Nayoung Kim, Amy Monahan, Jiaqing Tang, Andre Shamsabadi, Lea N. C. Rochet, Ioanna. A. A. Thanasi, Laura. R. R. de la Ballina, Charlotte. L. L. Rapley, Stephen Turnock, Elizabeth. A. A. Love, Laurence Bugeon, Margaret. J. J. Dallman, Martin Heeney, Gabriela Kramer-Marek, Vijay Chudasama, Federico Fenaroli, Molly. M. M. Stevens
Summary: This study describes a simple method for obtaining colloidally stable and low-fouling semiconducting polymer nanoparticles (SPNs) by grafting poly(ethylene glycol) (PEG) onto the polymer backbone. The functionalized SPNs can be specifically targeted to HER2-positive cancer cells by site-specifically clicking anti-HER2 antibodies, antibody fragments, or affibodies onto the SPN surface. In zebrafish embryos, the PEGylated SPNs show excellent circulation efficiency and the affibody-functionalized SPNs exhibit specific targeting towards HER2-expressing cancer cells in a xenograft model. This covalent PEGylated SPN system holds great potential for cancer theranostics.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Andre Shamsabadi, Tabasom Haghighi, Sara Carvalho, Leah C. C. Frenette, Molly M. M. Stevens
Summary: Nanozymes are nanosized materials that have catalytic properties similar to biological enzymes, making them promising candidates for clinical sensing devices. They can amplify signals in nanosensor-based platforms and improve sensor detection limits. Recent developments have led to highly effective nanozymes that can detect clinically relevant biomarkers, but there are hurdles to overcome before they can be used in clinical diagnostics. This overview discusses the current understanding of nanozymes for disease diagnostics and biosensing applications, and the challenges that need to be addressed for their translation into clinical tests.
ADVANCED MATERIALS
(2023)
Article
Biochemical Research Methods
Oystein ovrebo, Miina Ojansivu, Kimmo Kartasalo, Hanna M. G. Barriga, Petter Ranefall, Margaret N. Holme, Molly M. Stevens
Summary: RegiSTORM is a software that accurately registers multiple STORM channels by identifying fiducial markers in the sample and using them as landmarks for channel registration. It has been demonstrated to work effectively with and without fiducials.
BMC BIOINFORMATICS
(2023)
Article
Biotechnology & Applied Microbiology
Taras Sych, Jan Schlegel, Hanna M. G. Barriga, Miina Ojansivu, Leo Hanke, Florian Weber, R. Beklem Bostancioglu, Kariem Ezzat, Herbert Stangl, Birgit Plochberger, Jurga Laurencikiene, Samir El Andaloussi, Daniel Fuerth, Molly M. Stevens, Erdinc Sezgin
Summary: Lipid nanoparticles, viruses, exosomes and liposomes can be characterized using fluorescence fluctuations analysis. A method called single-particle profiler is introduced to provide information on the content and biophysical properties of thousands of particles within the size range of 5-200 nm. The single-particle profiler is utilized to measure mRNA encapsulation efficiency of lipid nanoparticles, viral binding efficiencies of different nanobodies, and the biophysical heterogeneity of liposomes, lipoproteins, exosomes and viruses.
NATURE BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Sebastien J. P. Callens, Daniel Fan, Ingmar A. J. van Hengel, Michelle Minneboo, Pedro J. Diaz-Payno, Molly M. Stevens, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Summary: The organization of bone cells in landscapes with varying curvatures was studied, revealing a preference for local concavities, multicellular bridging, and collective stress fiber orientation.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Biomedical
Hongya Geng, Emily J. Lupton, Yun Ma, Rujie Sun, Christopher L. Grigsby, Giulia Brachi, Xiaorui Li, Kun Zhou, Daniel J. Stuckey, Molly M. Stevens
Summary: The development of near-infrared light responsive conductive polymers provides a useful theranostic platform for malignant tumors. The self-assembly of ultrathin 2D polypyrrole nanosheets with tunable size distribution enables photoacoustic imaging and photothermal therapy. The pH-responsive features of the nanosheets show potential for accurate and highly efficient theranostics.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Multidisciplinary Sciences
Junfang Zhang, Yuntao Zhu, Christian Njel, Yuxin Liu, Pietro Dallabernardina, Molly M. Stevens, Peter H. Seeberger, Oleksandr Savateev, Felix F. Loeffler
Summary: In this study, a new synthesis strategy for carbon nitride photoelectrodes was introduced through advanced film generation techniques. This method involved spin coating pretreatment of a conductive substrate with a multipurpose polymer and a supramolecular precursor, followed by chemical vapor deposition to synthesize dual-layer carbon nitride photoelectrodes. The polymer improved the polymerization degree and electrical conductivity of carbon nitride, leading to state-of-the-art photoelectrochemical performance and high yields in C-H functionalization.
NATURE COMMUNICATIONS
(2023)
Review
Materials Science, Multidisciplinary
Ke Shi, Chuwen Song, Yayi Wang, Rona Chandrawati, Yiyang Lin
Summary: This review presents recent advances in the design of bioinspired systems that mimic transmembrane signaling in synthetic and living cells. The building of cell-like membranous structures and the construction of interfacial recognition between chemical or biological components are summarized. The possibilities of mimicking transmembrane signaling with transducer integrated systems are highlighted, along with the potential for applying supramolecular materials to interact with surface receptors on the plasma membrane.
COMMUNICATIONS MATERIALS
(2023)
Article
Materials Science, Biomaterials
Stephanie L. Fung, Jarrod P. Cohen, E. Thomas Pashuck, Catherine E. Miles, Joseph W. Freeman, Joachim Kohn
Summary: Tissue resorption and remodeling are important for successful healing and regeneration. This study focuses on the design of biomaterials that can respond to the regenerative processes in native tissue. By incorporating specific peptide sequences, the researchers have developed a tyrosol-derived peptide-polyester block copolymer that can be selectively degraded by proteases. The study demonstrates the potential of proteolytic-guided degradation in tissue regeneration.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Biochemical Research Methods
Vernon LaLone, Aleksandra Aizenshtadt, John Goertz, Froydis Sved Skottvoll, Marco Barbero Mota, Junji You, Xiaoyu Zhao, Henriette Engen Berg, Justyna Stokowiec, Minzhi Yu, Anna Schwendeman, Hanne Scholz, Steven Ray Wilson, Stefan Krauss, Molly M. Stevens
Summary: Confocal Raman spectral imaging (RSI) enables label-free visualization of molecules in biological specimens without sample preparation. qRamanomics, an integrated bioanalytical methodology, is developed to quantify the deconvoluted spectra for quantitative spatial chemotyping of biomolecules. It is applied to assess specimen variation and maturity in 3D liver organoids and identify biomolecular response signatures from liver-altering drugs, facilitating drug metabolism and accumulation monitoring.
CELL REPORTS METHODS
(2023)
