期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 139, 期 10, 页码 3623-3626出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.7b00065
关键词
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资金
- National Science Foundation [CHE-1307404, CTS-0120978]
- Binational Science Foundation [2014116]
- National Institutes of Health [MH110975]
We describe the preparation of cross linked, polymeric organic nanoparticles(ONPs) with a single, covalently linked DNA strand. The structure and functionalities of the ONPs are controlled by the synthesis of their parent linear block copolymers that provide monovalency, fluorescence and narrow size distribution. The ONP can also guide the deposition of chloroaurate ions allowing gold nanoparticles (AuNPs) to be prepared using the ONPs as templates. The DNA strand on AuNPs is shown to preserve its functions.
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