Deoxygenation of Ethers To Form Carbon-Carbon Bonds via Nickel Catalysis

In this article a successful protocol was developed to construct carbon carbon bonds by the extrusion of the O atom of ethers-via nickel catalysis in the presence of reductants. This methodology is featured as a highly economic route to construct sp(3)-sp(3) C-C bonds through dual C-O activation of ethers with good functional group tolerance.