Article
Environmental Sciences
Eka Djatnika Nugraha, June Mellawati, Wahyudi, Chutima Kranrod, Makhsun, Hirofumi Tazoe, Haeranah Ahmad, Masahiro Hosoda, Naofumi Akata, Shinji Tokonami
Summary: The study in Mamuju, Indonesia, found high levels of natural radionuclides and heavy metals in the soil, indicating moderate contamination. The pollution indices and correlation analyses showed potential hazards to human health in Mamuju due to the presence of Pb and other heavy metals. Measures need to be taken to address and monitor the environmental pollution in Mamuju.
Article
Remote Sensing
J. O. Ondieki, C. O. Mito, M. Kaniu
Summary: This study investigates the use of remote sensing and geographic information system techniques to accurately detect radioactive minerals in high background radiation areas. The study used spectral signatures of soil, rocks, and vegetation to infer the presence of radioactive minerals. Both unsupervised and supervised classification techniques were applied, and the findings were validated using air-absorbed gamma dose-rate measurements. The study demonstrates the general utility of remote sensing techniques in radioactive mineral surveys and environmental radiological assessments.
INTERNATIONAL JOURNAL OF APPLIED EARTH OBSERVATION AND GEOINFORMATION
(2022)
Article
Environmental Sciences
Masahiro Hosoda, Eka Djatnika Nugraha, Naofumi Akata, Ryohei Yamada, Yuki Tamakuma, Michiya Sasaki, Kevin Kelleher, Shinji Yoshinaga, Takahito Suzuki, Chanis Pornnumpa Rattanapongs, Masahide Furukawa, Masaru Yamaguchi, Kazuki Iwaoka, Tetsuya Sanada, Tomisato Miura, Kusdiana, Dadong Iskandar, Eko Pudjadi, Ikuo Kashiwakura, Shinji Tokonami
Summary: The study found a unique high natural radiation area in Indonesia where residents are exposed to chronic low dose-rate radiation. Indoor radon concentrations exceeded the reference levels recommended by the World Health Organization, and outdoor radon concentrations were comparable to high indoor levels. The annual effective dose due to external and internal exposures in the study area exceeded the dose limit for radiation workers, suggesting the need for further epidemiological studies on health effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Biochemistry & Molecular Biology
Olga V. V. Kolesnik, Tatiana V. V. Rozhko, Nadezhda S. S. Kudryasheva
Summary: Radioactive contaminants pose problems globally, particularly in marine ecosystems, and their ecological significance is expected to increase in the future. This review focuses on the bioeffects of various alpha and beta emitting radioisotopes (americium-241, uranium-235/238, thorium-232, and tritium) and gamma radiation, with a special emphasis on low-intensity exposures. Luminous marine bacteria are highlighted as representative organisms, and their bioluminescence intensity is widely used as a simple and sensitive bioassay parameter. The review discusses the relationship between bacterial luminescence response and exposure time and irradiation intensity, and also explores molecular intracellular processes under low-intensity radiation, including changes in enzymatic processes, consumption of NADH, the role of reactive oxygen species, and DNA damage repair. The results demonstrate the natural radioprotective function of humic substances.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biology
Khatuna Dondoladze, Marina Nikolaishvili, David Zurabashvili
Summary: The study aimed to investigate the effects of radon hormesis balneotherapy on the oxidant and antioxidant systems, as well as anxiety reactions in rats. Results showed that inhalation of radon led to a decrease in anxiety levels and activated antioxidant mechanisms. The rats in the radon therapy group showed less anxiety behavior compared to the control groups.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Yeh Siang Lau, Ming Tsuey Chew, Amal Alqahtani, Bleddyn Jones, Mark A. Hill, Andrew Nisbet, David A. Bradley
Summary: The concept of radiation-induced hormesis, where low doses are beneficial and high doses are detrimental, is gaining attention in various scientific fields. There is ongoing debate about the magnitude and mechanism of this hormetic dose response, which could have therapeutic implications for human health in the future. Studies explore both the beneficial and detrimental effects of low dose ionizing radiation-induced hormesis, along with the underlying mechanisms that may provide insights for future treatments.
APPLIED SCIENCES-BASEL
(2021)
Article
Immunology
Soha M. Hussien, Engy R. Rashed
Summary: This study investigated the role of cell-mediated immunological response in the adaptive response induced by low-dose ionizing radiation. The results showed that low-dose ionizing radiation can protect the body against high-dose radiation by suppressing the immune response.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
(2023)
Review
Chemistry, Analytical
Eka Djatnika Nugraha, Masahiro Hosoda, Yuki Tamakuma, Chutima Kranrod, June Mellawati, Naofumi Akata, Shinji Tokonami
Summary: Some areas around the world have anomalies with high natural radiation that may affect public health. Recent studies have found Mamuju, Indonesia, to be a unique high natural radiation area. The majority of relevant papers focus on monitoring, main sources, and influential factors related to radon and dose assessments.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2021)
Article
Energy & Fuels
Katarzyna Szkliniarz, Agata Walencik-Lata, Jan Kisiel, Kinga Polaczek-Grelik, Karol Jedrzejczak, Marcin Kasztelan, Jacek Szabelski, Jerzy Orzechowski, Przemyslaw Tokarski, Wlodzimierz Marszal, Marika Przybylak, Krzysztof Fulawka, Sebastian Gola
Summary: The natural radioactivity in underground locations is crucial for work safety and research experiments, and KGHM conducted a study on natural radioactivity, finding exceptionally low levels in the Polkowice-Sieroszowice mine.
Article
Oncology
Igor Shuryak, Lisa A. Kachnic, David J. Brenner
Summary: The respiratory disease COVID-19 became a global pandemic in 2020, with excessive inflammation believed to be a key factor in severe symptoms and death. Low-dose whole-lung radiation therapy is being considered as an anti-inflammatory treatment for severe pulmonary symptoms of COVID-19, but concerns about long-term risks remain. Studies found that the radiation-induced risks for lung cancer were generally higher than major coronary events, with the highest risks in female smokers and individuals with high heart disease risk factors treated between ages 50 and 60.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2021)
Article
Energy & Fuels
Agata Walencik-Lata, Katarzyna Szkliniarz, Jan Kisiel, Kinga Polaczek-Grelik, Karol Jedrzejczak, Marcin Kasztelan, Jacek Szabelski, Jerzy Orzechowski, Przemyslaw Tokarski, Wlodzimierz Marszal, Marika Przybylak, Robert Hildebrandt, Krzysztof Fulawka
Summary: Underground locations can be used for scientific and economic purposes, but natural radioactivity can affect the safety level. This article presents research on the natural radioactivity in shallow mine workings, including radon determination, gamma spectrometry, neutron flux measurements, and isotope measurements. The study found that the closing of the measurement chamber and turning off ventilation led to a significant increase in Rn-222 content.
Article
Environmental Sciences
Nimelan Veerasamy, Sharayu Kasar, Rajamanickam Murugan, Kazumasa Inoue, Thennaarassan Natarajan, Rakesh Chand Ramola, Masahiro Fukushi, Sarata Kumar Sahoo
Summary: The Chhatrapur-Gopalpur coastal area in Odisha, India is a well-known natural high background radiation (HBRA) area due to the abundance of monazite in beach sands and soils. Recent studies have found high concentrations of uranium and its decay products in groundwater, indicating that the soils in this area are the possible sources of these high uranium levels.
Article
Energy & Fuels
Agata Walencik-Lata, Katarzyna Szkliniarz, Jan Kisiel, Kinga Polaczek-Grelik, Karol Jedrzejczak, Marcin Kasztelan, Jacek Szabelski, Jerzy Orzechowski, Przemyslaw Tokarski, Wlodzimierz Marszal, Marika Przybylak, Lech Stolecki, Tomasz Selerowicz, Krzysztof Fulawka
Summary: There has been increasing interest in using underground locations for various applications, including research. In Poland, attempts have been made to build an underground laboratory, which requires a detailed analysis of natural radioactivity for selecting an appropriate location. This study presents detailed characteristics of natural background radiation near the Lubin mine, including photon flux, gamma-ray dose rate, thermal neutron flux, and radon concentration. Laboratory measurements show significant variations in the concentration of radioactive isotopes in rocks.
Review
Biochemistry & Molecular Biology
Stephen C. Bondy
Summary: Hormesis suggests that the effects of exposures to various materials or conditions on organisms may not have linear dose-response characteristics. This review aims to objectively examine the existence of hormesis and its potential mechanisms.
Review
Oncology
Eymeric Le Reun, Nicolas Foray
Summary: The article reviews the medical applications of low-dose radiation therapy (LDRT) and presents a unified mechanistic model based on radiation-induced nucleoshuttling of the ATM kinase. It highlights the discontinuity of the dose-response curve and the counterintuitive observation that a low dose may have a higher biological effect than a higher dose. The apparent paradox of specific radiobiological effects at low doses can be explained by the same mechanistic model.
Article
Biology
I. Slonecka, K. Lukasik, K. W. Fornalski
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2019)
Article
Pharmacology & Pharmacy
L. Dobrzynski, K. W. Fornalski, J. Reszczynska, M. K. Janiak
Article
Physics, Multidisciplinary
Krzysztof Wojciech Fornalski
EUROPEAN PHYSICAL JOURNAL PLUS
(2019)
Article
Chemistry, Physical
Krzysztof W. Fornalski, Lukasz Adamowski, Michal Bonczyk, Magdalena Winkowska-Struzik
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Physics, Multidisciplinary
K. W. Fornalski, J. Reszczynska, L. Dobrzynski, P. Wysocki, M. K. Janiak
ACTA PHYSICA POLONICA A
(2020)
Article
Pharmacology & Pharmacy
Maciej Pylak, Krzysztof Wojciech Fornalski, Joanna Reszczynska, Piotr Kukulski, Michael P. R. Waligorski, Ludwik Dobrzynski
Summary: This study applied three statistical methods - Bayesian, randomized data binning, and Maximum Entropy Method - to analyze US radon data and found that MEM was particularly effective in extracting meaningful results from data containing confounding factors. The analysis consistently demonstrated a decrease in the relative number of lung cancers with increasing radon concentrations and altitude of inhabited dwellings, while also showing a correlation between UVB intensity and lung cancer occurrence.
Article
Biology
I. Slonecka, J. Krasowska, Z. Baranowska, K. W. Fornalski
Summary: This paper proposes a novel method based on Bayesian statistics for assessing personal doses in mixed beta-gamma radiation fields, where the prior function and likelihood function are used to transform into the posterior probability distribution of the sought parameter and ultimately the dose value. The method is supported by analytical and Monte Carlo calculations.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2021)
Biographical-Item
Biology
Yehoshua Socol, Ludwig Feinendegen, Krzysztof W. Fornalski, Marek Janiak, Carmel Mothersill, Michael P. R. Waligorski
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Biology
Krzysztof W. Fornalski, Ludwik Dobrzynski
Summary: The Avrami equation, originally used in condensed matter physics to describe crystallization and nucleation processes, is applied to cancer physics to enhance the multi-hit model of carcinogenesis. This approach considers the cancer transformation as a volumetric process of single cell's DNA neoplastic transformation, with the probability function directly related to the number of oncogenic mutations. The proposed model provides a different perspective on multi-hit carcinogenesis and is tested on clinical data for gastric cancer, showing a relationship between cancer transformation and DNA fractal geometry.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Letter
Biology
Krzysztof W. Fornalski, Ludwik Dobrzynski
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Article
Biology
Krzysztof W. Fornalski, Lukasz Adamowski, Ludwik Dobrzynski, Rafal Jarmakiewicz, Aleksandra Powojska, Joanna Reszczynska
Summary: The priming dose effect, a special case of radiation adaptive response, involves applying a small dose prior to a high one to enhance repair of DNA damage and reduce mutation frequency. A new theoretical approach was proposed to explain this effect, and experimental data on lesions and chromosomal inversions supported its predictive power. The study also revealed a correlation between strong radioadaptation and weak cellular radiosensitivity.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Krzysztof Wojciech Fornalski
Summary: This article discusses the use of Lotka-Volterra equations to simulate an organism's response to ionizing radiation. The calculations show that both high and low radiation doses can affect the organism's equilibrium state.
APPLIED SCIENCES-BASEL
(2023)
Article
Pharmacology & Pharmacy
Krzysztof W. Fornalski, Lukasz Adamowski, Ernest Bugala, Rafal Jarmakiewicz, Marek Kirejczyk, Jakub Kopycinski, Julianna Krasowska, Piotr Kukulski, Lukasz Piotrowski, Julia Ponikowska, Joanna Reszczynska, Iwona Slonecka, Pawel Wysocki, Ludwik Dobrzynski
Summary: This review article presents a simplified biophysical model that describes the response of cells to ionizing radiation. The model, based on extensive studies, combines a comprehensive stochastic approach with detailed deterministic models to describe various biophysical and radiobiological phenomena, including tumor development, priming dose effect, and bystander effect.
Article
Nuclear Science & Technology
Krzysztof Wojciech Fornalski
Summary: The study presents a method for empirical approximations of the total cross section for X-ray and gamma radiation interaction with matter, considering all important physical effects, suitable for practical applications in radiation protection and shield designing.
JOURNAL OF NUCLEAR ENGINEERING AND RADIATION SCIENCE
(2021)
Article
Physics, Fluids & Plasmas
Krzysztof W. Fornalski
