Article
Energy & Fuels
Changjun Li, Xingfu Cai, Mingqing Xiao, Yonggang Huo, Peng Xu, Sufen Li
Summary: This study investigates the high-pressure tritium leakage problem, establishes a thermodynamic model for tritium leakage behavior, and analyzes the impact of different ventilation scenarios on tritium removal efficiency through numerical simulations.
FRONTIERS IN ENERGY RESEARCH
(2022)
Article
Geochemistry & Geophysics
Andrew C. Turner, Nicholas J. Pester, Markus Bill, Mark E. Conrad, Kevin G. Knauss
Summary: The hydrogen isotopic composition of methane can serve as an indicator of gas origins. This study presents experimental constraints on the kinetics of hydrogen isotope exchange between methane and supercritical water, showing that exchange rates vary with temperature and suggesting the influence of life activity and thermogenic natural gas systems. The findings have implications for understanding the signatures of methane and water on Earth and other planetary bodies.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2022)
Article
Chemistry, Physical
Zengqi Lu, Xiaolong Fu, Jiamao Li, Jingwei Hou, Guangming Ran, Chengjian Xiao, Xiaolin Wang
Summary: A hydrophobic microscopic reaction environment was constructed through the modification of mesoporous silica, which helped improve the catalytic activity of the LPCE reaction. The Pt@SBA-15-tetramethyldisilazane catalyst, prepared by modifying the SBA-15 carrier and loading metal Pt, exhibited a superhydrophobic structure with a water contact angle of 158 degrees. This structure enhanced the catalytic performance and prevented catalyst deactivation. Experimental results showed that the catalyst had good catalytic activity in tritium water and maintained high activity after 30 days.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Nuclear Science & Technology
Chan Woo Park, Sung-Wook Kim, Youngho Sihn, Hee-Man Yang, Ilgook Kim, Kwang Se Lee, Changhyun Roh, In-Ho Yoon
Summary: Protonated lithium metal compounds, prepared by acid treatment of lithium metal compounds, were found to effectively reduce deuterium concentration in water. The H+ in protonated lithium metal compounds can exchange more readily with hydrons in water compared to Li+ in pristine lithium metal compounds, and heavier isotopes are speculated to be more stably retained in the crystal structure. Protonated lithium manganese nickel cobalt oxide was observed to adsorb and retain twice as much tritium as protonated lithium manganese oxide and protonated lithium cobalt oxide in equilibrium state when reacted with tritiated water.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yan Li, Chenxu Zheng, Zhi-Jiang Jiang, Jianbo Tang, Bencan Tang, Zhanghua Gao
Summary: A regioselective deuteration at the beta- and gamma-position of pyridines is achieved by using a combination of (KOBu)-Bu-t and DMSO-d(6), replenishing the prevailing alpha-deuteration of the pyridine systems. Preliminary mechanistic studies suggest that the dimsyl carbanion acts as one of the key intermediates.
CHEMICAL COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Da Zhao, Roland Petzold, Jiyao Yan, Dieter Muri, Tobias Ritter
Summary: Tritium labelling is a critical tool for pharmacokinetic and pharmacodynamic studies, and tritium gas is preferred for labelling due to its high isotopic purity. While heterogeneous catalysts like palladium supported on carbon are commonly used for tritiation reactions, their reaction mechanism can result in the reduction of other functional groups present in pharmaceuticals.
Article
Chemistry, Physical
Zengqi Lu, Xiaolong Fu, Jingwei Hou, Lei Yue, Jiamao Li, Guangming Ran, Chengjian Xiao, Xiaolin Wang
Summary: To enhance hydrogen-water isotope exchange performance, a hydrophobic microenvironment was created within the catalyst support and a bimetal catalyst was utilized. The superhydrophobic catalyst exhibited significant improvement in performance. Adsorption/desorption tests demonstrated that the hydrophobic microenvironment increased the diffusion rate of reactants, while metal doping modification enhanced reactant concentration around the active site. Overall, the catalytic performance of the catalyst with the hydrophobic microenvironment exceeded that of normal hydrophobic catalysts, even with slightly diminished hydrophobicity.
CATALYSIS COMMUNICATIONS
(2023)
Article
Engineering, Mechanical
Bharat Kumar, Deepak Kumar, V. Chaudhry
Summary: Core components of nuclear reactor, made of zirconium alloys, are susceptible to low amplitude vibration leading to material wear at contact interface. Reciprocating wear tests were conducted between zircaloy-4 (Zr-4) under dry and water-submerged conditions, along with wear tests between Zr-4 and stainless steel to confirm material transfer due to adhesion. Analysis using SEM, FESEM, EDS, Raman spectroscopy, and XPS revealed that coefficient of friction (COF) increases with fretting duration but decreases with frequency and displacement amplitude. Greater COF was observed under dry condition compared to submerged condition, with wear mechanism transitioning from adhesion to abrasion as displacement amplitude increased.
TRIBOLOGY INTERNATIONAL
(2023)
Article
Nuclear Science & Technology
Timur Kulsartov, Zhanna Zaurbekova, Regina Knitter, Asset Shaimerdenov, Yevgen Chikhray, Saulet Askerbekov, Assyl Akhanov, Inesh Kenzhina, Gunta Kizane, Yergazy Kenzhin, Magzhan Aitkulov, Darkhan Sairanbayev, Yuriy Gordienko, Yuriy Ponkratov
Summary: This work presents preliminary experimental data on the gas release from two-phase lithium ceramics Li4SiO4-Li2TiO3 under neutron irradiation conditions. The results show that tritium and helium can be released from the ceramic samples under certain irradiation conditions, and the release properties have been analyzed.
NUCLEAR MATERIALS AND ENERGY
(2022)
Article
Energy & Fuels
Ahmed Saad Soliman, Li Xu, Junguo Dong, Ping Cheng
Summary: This study investigates the thermal and electrical performance of an uncooled polycrystalline concentrated photovoltaic module under different environmental conditions, revealing that the CPV system can safely operate at specific solar concentration ratios, which holds significant practical value.
Article
Agronomy
Peirong Liu, Xiaojuan Tong, Ping Meng, Jinsong Zhang, Jun Li, Jingru Zhang, Yu Zhou
Summary: Ecosystem water use efficiency (WUE) is influenced by diffuse radiation, which can increase carbon assimilation and reduce water loss. The diffuse fraction (DF) has direct and indirect effects on WUE through altering biophysical factors such as photosynthetically active radiation (PAR), vapor pressure deficit (VPD), and canopy conductance (gc). WUE is primarily regulated by VPD and gc, with VPD having a remarkable indirect effect through stomatal behavior.
AGRICULTURAL AND FOREST METEOROLOGY
(2022)
Article
Chemistry, Physical
Kanchan Dutta, Mohsen Shahryari, Chao-Jun Li, Jan Kopyscinski
Summary: In this study, the rate-limiting step for the direct non-oxidative methane coupling to ethylene over gallium-nitride catalysts, which is the second C-H bond cleavage in methane to form methylene, was investigated. Isotope labelled experiments, in-situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), 13C solid state-NMR, and kinetic modelling were used to decipher the reaction mechanism. The results showed that the supported GaN/SBA-15 catalyst had more aliphatic surface intermediates (CH3* and CH2*) compared to unsupported GaN catalysts, which had higher amounts of aromatics intermediates and coke deposition. The kinetic study confirmed the likelihood of the reaction pathway involving the fast abstraction of the first H from CH4 to form methyl (CH3*) surface intermediates, followed by the slow second C-H bond cleavage to form methylene (CH2*) and subsequent coupling to ethylene.
APPLIED CATALYSIS A-GENERAL
(2023)
Article
Chemistry, Physical
Xiaofeng Dong, Xiaoan Lv, Junwei Huang, Yue Chang, Xiaona Ren, Changchun Ge
Summary: Sodium titanate, with its superior ion adsorption ability, holds potential for the production of high-quality antibacterial agents. However, the complex preparation process and difficulty of recovery have limited its applications until now. In this study, sodium titanate was successfully synthesized under mild conditions using reactants with higher potential energy, resulting in a hierarchical structure and increased specific surface area. This sodium titanate powder demonstrated a high adsorption capacity for Ag ions, reaching 486.9 mg/g (32.7 wt%) within one minute, with estimated active sites of about 4.51 mmol/g. Additionally, sodium titanate exhibited excellent antibacterial performance against E. coli after loading Ag ions, achieving an antibacterial efficiency of 99.68% within 20 minutes, and MIC and MBC values of 12.5 mg/L and 200 mg/L, respectively.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Plant Sciences
Mura Jyostna Devi, Vangimalla R. Reddy, Dennis Timlin
Summary: This study examined the physiological, biochemical, and molecular response of maize under different evaporative demand and soil water content conditions. The results showed that severe drought coupled with high vapor pressure deficit significantly decreased plant development by modifying enzymes, ABA, and transcription factors.
Article
Food Science & Technology
Jia Cao, Xiaohong Tong, Mengmeng Wang, Tian Tian, Sai Yang, Mingyue Sun, Bo Lyu, Xinru Cao, Huan Wang, Lianzhou Jiang
Summary: The study investigated the effects of sodium alginate and pH value on the formation and properties of soybean protein isolate/sodium alginate microparticles, revealing changes in protein structure, surface characteristics, and thermal stability. Under pH 9.0, the microparticles exhibited optimal physicochemical properties.
Article
Chemistry, Physical
Vitalii A. Bunyaev, Alexey Shnitko, Maria G. Chernysheva, Alexander L. Ksenofontov, Gennadii A. Badun
Summary: The study revealed that lysozyme directly adsorbs on graphene oxide by forming bonds with specific amino acid residues on the GO surface, leading to conformational changes. These changes, while not significant, increase the availability of active sites on the enzyme for binding with substrates after desorption.
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
(2022)
Article
Chemistry, Multidisciplinary
Maria G. Chernysheva, Artem V. Sinolits, Valeria S. Votyakova, Andrey G. Popov, Gennadii A. Badun
Summary: Hyaluronic acid shows potential as a coating to improve the biocompatibility of nanodiamond-antibiotic composites. The adsorption of hyaluronic acid is found to be higher on nanodiamonds with initially negative zeta-potential, after pre-adsorption of Miramistin, but still lower than on positively charged nanodiamonds unaffected by Miramistin. The maximum adsorption of hyaluronic acid is observed when Miramistin neutralizes the surface charge of nanoparticles.
MENDELEEV COMMUNICATIONS
(2022)
Article
Chemistry, Medicinal
V. P. Shevchenko, L. A. Andreeva, K. Shevchenko, I. Yu Nagaev, N. F. Myasoedov
Summary: Peptide derivatives of dopamine and serotonin acylated with lauric acid and oleic acid were synthesized and their permeability through artificial membranes was evaluated. A mass spectrometric method was developed to assess the content of these derivatives in phosphate buffered saline. The comparative permeability of the blood-brain barrier was determined using the parallel artificial membrane permeability assay, and derivatives acylated by lauric acid were found to be the most promising for overcoming the barrier.
PHARMACEUTICAL CHEMISTRY JOURNAL
(2022)
Article
Energy & Fuels
Andrey G. Kazakov, Taisya Y. Ekatova, Julia S. Babenya, Sergey E. Vinokurov, Gennady A. Badun
Summary: To date, a large amount of long-lived radioactive materials, including Ra-226, have been accumulated in the world. In our study, we investigated the phase distribution of 18C6 and its derivatives using tritium labeling and developed chromatographic purification methods. The distribution of these compounds between various organic solvents and water was studied in detail, providing valuable data for the selective recovery of Ra-226 from aged sources.
Article
Biochemistry & Molecular Biology
Ivan S. Chaschin, Maria A. Sinolits, Gennadii A. Badun, Maria G. Chernysheva, Nelya M. Anuchina, Sergey V. Krasheninnikov, Georgiy A. Khugaev, Antonina A. Petlenko, Dmitry V. Britikov, Alexander V. Zubko, Alexey D. Kurilov, Elizabet I. Dreger, Natalia P. Bakuleva
Summary: A tightly bonded polymer shielding coating can be obtained on a biomatrix by sequentially depositing chitosan and hyaluronic acid in a carbonic acid solution. This coating enhances the functionality of medical devices and bioprostheses and has the potential to induce antimicrobial response.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Marina A. Orlova, Vasiliy V. Spiridonov, Gennadii A. Badun, Tatiana P. Trofimova, Alexey P. Orlov, Alena S. Zolotova, Anna B. Priselkova, Gleb Yu. Aleshin, Maria G. Chernysheva, Alexander A. Yaroslavov, Stepan N. Kalmykov
Summary: Using a mouse model, the distribution of carboxymethyl cellulose microgels cross-linked with 67Cu2+ ions in different organs was investigated. The results showed clearance of the microgels through the liver and kidneys, and no release of copper from the microgels in vivo.
MENDELEEV COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
V. P. Shevchenko, I. Yu Nagaev, N. F. Myasoedov
Summary: This article summarizes the main approaches to incorporate tritium and deuterium labels into biologically active compounds and describes the preparation of organic compounds labeled with hydrogen isotopes using various physicochemical methods. The effect of reaction conditions on the yield and content of hydrogen isotopes in labeled preparations is considered, with a focus on the incorporation of deuterium and tritium through isotope exchange. Possible mechanisms for the incorporation of hydrogen isotopes and their distribution in organic compounds are demonstrated, and it is shown that irradiation of preparations, the use of intermediates, and other innovations can significantly improve the parameters of the desired labeled biologically active compounds.
Article
Chemistry, Analytical
Ya-Tong Zhao, Chao Wu, Shuai Yan, Chuan Wang, Zhiliang Huang, Qiao-Guo Tan, Rong Ji, Liuyan Yang, Chenghua Sun, Gennadii A. Badun, Maria G. Chernysheva, Ping Wang, Ai-Jun Miao
Summary: Humic substances (HS), abundant natural organic matter, play important roles in global carbon and nitrogen cycling and transport of contaminants. This study demonstrates the direct effects of HS on different organisms and reveals the accumulation behavior of HS in the nucleus of cells and other specific regions. The findings provide new insights into the ecological behavior of HS and its potential impacts.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Maria G. Chernysheva, Ivan S. Chaschin, Gennadii A. Badun, Viktor G. Vasil'ev, Ivan V. Mikheev, Tianyi Shen, Maria A. Sinolits, Natalia P. Bakuleva
Summary: Nanodiamond adsorption coatings can enhance the mechanical properties of collagen tissue. Negatively charged nanodiamonds have a stronger impact on the mechanical characteristics. A graphene layer can prevent tissue calcification. Nanodiamond and chitosan films significantly enhance the mechanical properties of bovine pericardium.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Medicinal
V. P. Shevchenko, I. Yu. Nagaev, A. V. Lopachev, N. F. Myasoedov
Summary: The efficiency of isotopic exchange using a homogeneous base (Et3N) and heterogeneous catalysts was compared. When using Et3N, the incorporation of deuterium into ouabain reached an average of about 3.26 atoms, but the yield was limited to 15-20%. The use of 5% Pd/BaSO4 catalyst was found to be the best for obtaining preparative amounts of labeled ouabain. The reaction carried out at 125oC for 30 min yielded a product with a 77% yield and an average content of 2.14 deuterium atoms per molecule. The use of heterogeneous catalysts simplified the purification process by reducing the number of by-products compared to Et3N.
PHARMACEUTICAL CHEMISTRY JOURNAL
(2023)
Article
Polymer Science
Evgenii I. Perepelkin, Maria A. Sinolits, Gennadii A. Badun, Maria G. Chernysheva, Nelya M. Anuchina, Sergey S. Abramchuk, Eduard E. Levin, Natalia P. Bakuleva, Dmitrii A. Popov, Ivan S. Chaschin
Summary: Firmly bonded antimicrobial protective coating made of chitosan nanoparticles has been developed for enhancing the functionality of medical devices, especially bioprosthetic heart valves in cardiac surgery. The coating is obtained using a biocompatible and self-neutralizing carbonic acid as a polymer solvent. This unique approach allows the formation of stable chitosan nanoparticles in carbonic acid solution and the doped nanoparticles show enhanced deposition and antimicrobial activity when applied on the biomatrix.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Analytical
V. P. Shevchenko, I. Yu. Nagaev, N. F. Myasoedov, S. L. Stvolinskii
Summary: The efficiency of isotope exchange was compared between gaseous deuterium and deuterium water as deuterium sources. It was found that exchange with deuterium water is preferable, as it ensures a more uniform distribution of deuterium. Additionally, the use of deuterium water allows for a reduction in the amount of unlabeled isotopomer and achieve higher yield and greater incorporation of deuterium.
Article
Biochemistry & Molecular Biology
V. P. Shevchenko, I. Yu. Nagaev, T. N. Fedorova, N. F. Myasoedov
Summary: The effect of temperature on the incorporation of deuterium into pyrrolylcarnosine was studied. Using deuterated water as a source of deuterium, it was found that isotope exchange can be carried out to obtain labeled pyrrolylcarnosine. Higher temperatures result in a more even incorporation of deuterium. The use of deuterated water reduces the amount of unlabeled isotopomer and increases the yield and deuterium content of the product.
DOKLADY BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Chemistry, Physical
Tianyi Shen, Maria G. Chernysheva, Gennadii A. Badun, Andrey G. Popov, Alexander Egorov, Neli M. Anuchina, Ivan S. Chaschin, Natalia P. Bakuleva
Summary: The research found that nanodiamonds can form adsorption complexes with levofloxacin and amikacin, reducing the dose of antibiotics used and decreasing their use in the postoperative period.
COLLOIDS AND INTERFACES
(2022)
Article
Biotechnology & Applied Microbiology
Moustafa R. Yehia, Tatyana E. Smolyarova, Alexandr V. Shabanov, Ekaterina S. Sushko, Gennady A. Badun, Nadezhda S. Kudryasheva
Summary: This study aimed to adapt a bioluminescent bacteria-based bioassay to monitor the bioeffects of gold nanoparticles. The results showed that gold nanoparticles can induce bioluminescent response and increase in bacteria size, and there is a relationship between bioluminescence activation and bacterial ROS consumption.
BIOENGINEERING-BASEL
(2022)
