Article
Chemistry, Multidisciplinary
Yanzhao Pang, Mingliang Jin
Summary: A highly aligned AgNW array film was prepared using a self-assembly method, which showed excellent signal reproducibility and detection ability at low concentrations. The uniform distribution of hot spots inside the AgNW substrate amplified the SERS signal.
Article
Chemistry, Physical
Debanjan Bagchi, Avijit Maity, Soumya Kanti De, Anjan Chakraborty
Summary: For the first time, this study reports the existence of different metastable intermediate states during the self-assembly process of phenylalanine in the presence of various metal ions. The metal ion-amino acid interactions lead to the initial formation of spherical aggregates, which then transform into other structures. These findings contribute to a better understanding of the role of metal ions in amino acid self-assembly.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Polymer Science
T. P. Tuyen Dao, Lubomir Vezenkov, Gilles Subra, Vincent Ladmiral, Mona Semsarilar
Summary: This study aims to produce self-assembled structures with hydrophobic polypeptide cores using RAFT-mediated PISA. Different hydrophobic monomers were polymerized under varying conditions to form diblock copolymer nano objects, resulting in a range of morphologies influenced by the peptides self-assembling core.
Article
Chemistry, Physical
Jorge M. del Campo, Joel Ireta
Summary: The hydrophobic dipeptide crystals are unusually stiff, with Young's moduli in the range of 19.7-33.3 GPa, primarily dictated by the strength and orientation of the hydrogen bond network.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Chemistry, Physical
Hyojin Park, Yuseok Kim, Yerin Kim, Cheoljae Lee, Hyosik Park, Hyeonseo Joo, Ju Hun Lee, Ju-Hyuck Lee
Summary: In this study, an eco-friendly and cost-effective approach was developed to align piezoelectric FF nanotubes using an ethanol-water solvent system. The fabricated FF nanotubes showed unidirectional polarization and strong piezoelectric properties comparable to those synthesized using toxic and expensive HFIP solvent. Furthermore, the FF-based piezoelectric nanogenerator generated significant voltage, current, and power outputs, making it a promising energy source for future biomedical applications.
APPLIED SURFACE SCIENCE
(2023)
Article
Nanoscience & Nanotechnology
Shuang Lin, Haoyu Guan, Yuqi Liu, Shinian Huang, Junming Li, Wuliji Hasi, Yizhuo Xu, Jixin Zou, Bin Dong
Summary: Tuning and controlling the plasmon coupling of noble metal nanoparticles are crucial for enhancing their responses in near-field and far-field. A novel heterogeneous plasmonic assembly with a controllable hot spot model was proposed in this work, showing significant enhancement for SERS behavior in point-to-facet hotspots. The binary assemblies of Au NS doping in Au@Ag NCs demonstrate excellent sensitivity and high reproducibility in the identification of ketamine, indicating a new avenue for fabricating plasmonic metal materials with collective LSPR properties and sensitive SERS behavior.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Marius Schumacher, Dorleta Jimenez de Aberasturi, Jan-Philip Merkl, Leonardo Scarabelli, Elisa Lenzi, Malou Henriksen-Lacey, Luis M. Liz-Marzan, Horst Weller
Summary: This study introduces a versatile strategy for the preparation of colloidally stable and biocompatible gold nanoparticle clusters. By tuning the ligand ratio on the surface of each nanoparticle, aggregation can be controlled. The resulting clusters exhibit enhanced surface plasmon resonances and electromagnetic hotspots for surface-enhanced Raman scattering (SERS), making them promising bioimaging agents. These clusters also demonstrate high cellular uptake and low cytotoxicity, allowing for potential applications in cellular imaging.
ADVANCED OPTICAL MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Miaomiao Jin, Zhanxin Song, Wei Liu, Zilu Zhou, Guozhen Wang, Mo Xian
Summary: Peptide-assisted self-assembly enhances the stability of Al and CuO nanoparticles in aqueous solution, and the energy release of peptide-assembled Al/CuO nanothermite is 26% higher than that of physically mixed samples in phosphate buffer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
Di Liu, Huimin Gao, Wenji Jiang, Su Yan, Hao Liu, Junjie Chen, Sisi Wen, Wei Zhang, Xu Wang, Bing Zhao, Wei Song
Summary: In this study, three-dimensional Ag aerogel-supported Hg single-atom catalysts were used as an efficient SERS substrate for monitoring enhanced oxidase-like reactions. The effect of Hg2+ concentrations on the SERS properties of 3D Hg/Ag aerogel networks was investigated, and an optimized addition of Hg2+ resulted in specific enhancement. The formation of Ag-supported Hg SACs was confirmed using HAADF-STEM imaging and XPS measurement, and the oxidase-like catalytic mechanism of Hg/Ag SACs was revealed using DFT. This research provides a mild synthetic strategy for fabricating Ag aerogel-supported Hg single atoms with promising prospects in various catalytic fields.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lanxin Xu, Jiali Ma, Guodong Wei, Chenjie Gu, Tao Jiang
Summary: This study introduces a novel self-energized hybrid substrate for surface-enhanced Raman scattering (SERS) technique, utilizing a distinctive piezoelectric polyvinylidene fluoride (PVDF) film and hydrophilic-hydrophobic strategy. By pressing or bending the PVDF film, the enhanced localized electromagnetic field of Ag nanoparticles (Ag NPs) can be rationally induced, leading to tunable ultra-high sensitivity. The quantitative level of detection is further improved by uniformly anchoring and enriching analytes using a facile hydrophilic-hydrophobic strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Physical
Olamilekan Joseph Ibukun, Milan Gumtya, Surajit Singh, Ananda Shit, Debasish Haldar
Summary: We designed and synthesized a series of FF peptide mimetics with different spacers to study their structure and self-assembly. The results help understand biomolecular aggregation and provide a strategy to obtain fractal pattern materials.
Article
Chemistry, Multidisciplinary
I. A. Brezestean, N. Tosa, A. Falamas, D. Cuibus, C. M. Muntean, A. Bende, B. Cozar, C. Berghian-Grosan, C. Farcau
Summary: This study reports on the use of self-assembled colloidal nanoparticle films for Surface Enhanced Raman Spectroscopy (SERS) analysis of pesticides. The results demonstrate the high sensitivity and selectivity of this technique, making it suitable for applications in the food industry and environmental monitoring.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Qi Li, Mingju Xian, Anhe Wang, Yi Jia, Shuo Bai, Xuehai Yen, Junbai Li
Summary: Dipeptides are biocompatible building blocks that can be assembled into various sensing materials. These sensors interact with force, electricity, light, and chemical stimulus to generate electrical, optical, and mechanical signals, making them applicable in microelectronics and healthcare fields. Dipeptide-based sensing materials have the advantages of biological molecules and also possess excellent mechanical and electrical properties. This perspective article summarizes the molecular assembly of dipeptides, focusing on their application as biogenic sensors, and discusses the challenges and prospects for the future development of dipeptide-based sensing materials.
Article
Chemistry, Physical
Junnan Wang, Minqiang Wang, Jindou Shi, Yun Zhou, Chen Zhang, Arshad Saleem Bhatti
Summary: Flexibility and self-cleaning are important areas of research in the development of plasma substrates in Surface-enhanced Raman scattering (SERS). This study presents a flexible composite Au@Ag/ultrathin g-C3N4/Graphene (AUG) film, based on a PDMS film, used as a highly sensitive SERS substrate for detecting rhodamine 6G (R6G) molecules. The AUG flexible composite film displayed a detection limit of 10-12 M for R6G molecules, maintained 83% of SERS activity after 10 photocatalytic cycles, and had only a 5% decrease in SERS detection performance after 30 days of storage in air. The facile fabrication process makes the AUG composite film an excellent candidate for flexible, inexpensive, and stable wearable SERS sensing systems.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
Mathias Charconnet, Matiyas Tsegay Korsa, Soren Petersen, Javier Plou, Christoph Hanske, Jost Adam, Andreas Seifert
Summary: Periodic superlattices of noble metal nanoparticles with well-defined strong hotspots are achieved by a chemically driven, templated self-assembly process. This technology allows for the assembly of nanoparticles with various shapes, resulting in homogeneous nanoparticle clusters on a centimeter scale. Electromagnetic simulations and experimental measurements demonstrate excellent agreement, confirming the specific near-field behavior and surface-enhanced Raman scattering enhancement factors of the periodic arrays of nanoparticles.
Article
Dentistry, Oral Surgery & Medicine
Michael T. Brennan, Lars Siim Madsen, Deborah P. Saunders, Joel J. Napenas, Christine McCreary, Richeal Ni Riordain, Anne Marie Lynge Pedersen, Stefano Fedele, Richard J. Cook, Rafik Abdelsayed, Maria T. Llopiz, Vidya Sankar, Kevin Ryan, Donna A. Culton, Yousra Akhlef, Fausto Castillo, Inti Fernandez, Sabine Jurge, Alexander R. Kerr, Chad McDuffie, Tim McGaw, Alan Mighell, Thomas P. Sollecito, Thomas Schlieve, Marco Carrozzo, Athena Papas, Thomas Bengtsson, Ibtisam Al-Hashimi, Laurie Burke, Nancy W. Burkhart, Shauna Culshaw, Bhavik Desai, Jens Hansen, Pia Jensen, Torkil Menne, Paras B. Patel, Martin Thornhill, Nathaniel Treister, Thomas Ruzicka
Summary: This clinical trial demonstrated that the use of Rivelin(R)-CLO patches for the treatment of OLP showed significant efficacy in improving ulcer area, symptom severity, disease activity, pain, and quality of life compared to placebo, with a favorable safety profile.
JOURNAL OF ORAL PATHOLOGY & MEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Ahmed T. Alanazi, Sawsan Almohammed, James H. Rice
Summary: This study explores the potential of using cadmium sulfide combined with plasmonic nanostructures for photo-induced catalysis. The researchers found that when a silver nanowire and cadmium sulfide composite are irradiated with super-bandgap light, dimercaptoazobenzene is formed from p-aminothiophenol. These results suggest that cadmium sulfide can be a viable alternative to semiconductors like titanium dioxide for plasmonic photocatalysis applications.
Article
Chemistry, Multidisciplinary
Agata Fularz, Sawsan Almohammed, James H. Rice
Summary: Metal-free cellulose-based substrates can enhance fluorescence signals by nanofiber-driven clustering of analyte molecules, allowing detection of molecules at concentrations as low as 100 nM.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Sawsan Almohammed, Agata Fularz, Mohammed Benali Kanoun, Souraya Goumri-Said, Abdullah Aljaafari, Brian J. Rodriguez, James H. Rice
Summary: Semiconducting materials are proposed as alternatives to noble metal nanomaterials to enhance Raman scattering. Bioinspired semiconducting diphenylalanine peptide nanotubes annealed through a structural transition were demonstrated to support Raman detection of molecules, including mononucleotides, at concentrations as low as 10(-7) M. The enhancement is achieved by introducing electronic states below the conduction band to facilitate charge transfer to the analyte molecule. This study shows that organic semiconductor-based materials can serve as platforms for enhanced Raman scattering for chemical sensing, without the need for electromagnetic surface-enhanced Raman spectroscopy.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Ahmed T. Alanazi, James H. Rice
Summary: Combining plasmonic and semiconductors offers significant potential in creating sensing and photocatalytic devices. This work demonstrates the use of conducting polymer materials with plasmonic nanomaterials to boost plasmon-enhanced Raman scattering spectroscopy signal strength and support oxidation of target molecules.
MATERIALS RESEARCH EXPRESS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Dina Taimeh, Richeal Ni Riordain, Stefano Fedele, Rachel Leeson
Summary: This study aimed to explore the experiences of patients with TMDs in the National Health Service and their healthcare priorities when seeking treatment. Semi-structured interviews were conducted, and thematic analysis was used to identify key themes. The findings highlighted challenges and needs related to accessing appropriate care, receiving a diagnosis and sufficient information, interacting with clinical staff, treatment strategies and support.
Article
Dentistry, Oral Surgery & Medicine
Stefano Fedele, Arwa Al-Hamad, Valeria Mercadante, Stephen Porter, David Isenberg, Ana Poveda-Gallego, Sarah. T. T. Brown
Summary: This study explored the feasibility of salivary electrostimulation in individuals with primary Sjogren's syndrome and provided parameters for future phase III trials. The results showed that salivary electrostimulation could improve dry mouth symptoms in patients with Sjogren's syndrome without adverse events. The completion of this study provides reliable evidence for future trials.
JOURNAL OF ORAL PATHOLOGY & MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Sawsan Almohammed, Mohammed Benali Kanoun, Souraya Goumri-Said, Mir Waqas Alam, Agata Fularz, Abdullah Alnaim, James H. H. Rice, Brian J. J. Rodriguez
Summary: Self-assembling nanostructured peptide gels, particularly Fmoc-FF gels, offer promising applications in sensing, drug delivery, and energy harvesting. By controlling the water content and temperature, the structure tunability of Fmoc-FF gels can be achieved. Incorporating metal nanoparticles in the gel formation allows for optical sensing applications. The observations also suggest the potential use of these peptide materials in bioimaging and sensing applications.
Article
Dentistry, Oral Surgery & Medicine
Dina Taimeh, Richeal Ni Riordain, Stefano Fedele, Rachel Leeson
Summary: The aim of this study is to develop a patient-reported experience measure to evaluate the clinical experience of patients with temporomandibular disorders. Input from various sources, including literature, patients, and experts, was utilized to develop a preliminary questionnaire, which underwent cognitive testing to generate the final measure. This measure effectively evaluates the clinical experience of patients and has gained recognition with patient involvement.
JOURNAL OF ORAL PATHOLOGY & MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Waleed Alamoudi, Richeal Ni Riordain, Stefano Fedele, Stephen Porter
Summary: This study aims to evaluate the content and quality of audiovisual online information about OED. The findings show that most of the materials are scientific in nature, with poor quality and lacking essential patient information. However, these materials could still be useful for patient education with improvements needed.
Article
Dentistry, Oral Surgery & Medicine
Abdullah Alsoghier, Richeal Ni Riordain, Stefano Fedele, Stephen Porter
Summary: This study aimed to assess the information needs of patients with chronic oral diseases and the agreement between clinicians and patients on important topics. The results showed that there were unmet needs regarding dysplasia, and clinicians were not able to fully predict patients' priorities.
Article
Dentistry, Oral Surgery & Medicine
Dina Taimeh, Richeal Ni Riordain, Stefano Fedele, Rachel Leeson
Summary: This study explored the structural validity and internal consistency reliability of General Anxiety Disorder-7, Patient Health Questionnaire-8, 15, and Jaw Functional Limitation Scale-20 in patients with chronic pain of temporomandibular disorders. The results showed positive evidence of structural validity and internal consistency of these questionnaires, suggesting their suitability for use in evaluating chronic pain in temporomandibular disorder patients.
