Article
Endocrinology & Metabolism
Md. Mahiuddin Zahangir, Md. Shahjahan, Hironori Ando
Summary: Kisspeptin plays an important role in reproductive regulation in animals. In grass puffer, kisspeptin has different effects depending on the reproductive stage, and it mainly acts by regulating the expression of genes in the hypothalamic-pituitary-gonadal axis.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Nayan Mate, Rohit Shaji, Moitreyi Das, Sammit Jain, Arnab Banerjee
Summary: This study suggests that the expression of polyamines, GnRH-I, and GnIH in the hypothalamus of female mice undergoes variation during aging, and polyamines may regulate the expression of GnRH-I. The study also reveals the effects of polyamines, lactate, and TNF-alpha on GnRH-I expression in GT1-7 cells, as well as the potential neuro-protective role of polyamines. Furthermore, the study identifies differentially expressed genes in GT1-7 cells treated with putrescine and TNF-alpha.
Article
Endocrinology & Metabolism
Richa Soni, Chandana Haldar, Chandra Mohini Chaturvedi
Summary: The study on Japanese quail revealed that retinal and extra-retinal photoreceptors play a crucial role in regulating reproductive processes and hormonal activities, with close correlations to melatonin receptors and other factors.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2021)
Review
Physiology
Md. Mahiuddin Zahangir, Mohammad Lutfar Rahman, Hironori Ando
Summary: Fish are poikilotherm and susceptible to changes in water temperature which can affect reproduction through the disruption of neuroendocrine mechanisms. Anomalous high and low temperatures directly impact the expression of genes involved in reproductive regulation, potentially leading to the termination of reproductive activity. The grass puffer provides a model for studying how thermal fluctuations influence the reproductive neuroendocrine system and gene expression.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Obstetrics & Gynecology
Takeshi Iwasa, Yuri Yamamoto, Hiroki Noguchi, Asuka Takeda, Saki Minato, Shuhei Kamada, Junki Imaizumi, Tomohiro Kagawa, Atsuko Yoshida, Takako Kawakita, Kanako Yoshida
Summary: Undernourished conditions disrupt female reproductive functions by reducing gonadotrophin-releasing hormone (GnRH) secretion in the hypothalamus. Hypothalamic factors play important roles in coordinating reproductive functions and energy homeostasis. Anorexigenic/satiety-related factors promote GnRH secretion, while orexigenic factors attenuate GnRH secretion. Kisspeptin, a potent stimulator of GnRH, is also reduced under undernourished conditions to prioritize individual survival.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Anna Vostrizansky, Andrew Barce, Zoe Gum, Daniel J. Shafer, Debbie Jeffrey, Gregory S. Fraley, Phillip D. Rivera
Summary: The presence or absence of light during pre-hatch incubation does not affect the overall post-hatch production of Pekin ducks, but further research is needed to explore the impact of light on their post-hatch development and growth.
Article
Behavioral Sciences
Christine Horne, Jon Vidar Helvik, Mitchell Stewart Fleming, Per Gunnar Fjelldal, Mariann Eilertsen
Summary: This study provides a comprehensive topographic mapping of key neuroendocrine cells related to sexual maturation in the brain of mature Atlantic salmon, revealing that the diencephalic and midbrain regions seem to play central roles in controlling sexual maturation.
BRAIN BEHAVIOR AND EVOLUTION
(2023)
Review
Endocrinology & Metabolism
Kazuyoshi Tsutsui, Takayoshi Ubuka, Kazuyoshi Ukena
Summary: The discovery of GnIH in 2000 has revolutionized the field of reproductive neuroendocrinology by demonstrating its role as a key neurohormone inhibiting reproduction in vertebrates. GnIH acts through the GPR147 receptor to reduce gonadotropin release and synthesis, impacting both reproductive behavior and neuroendocrine function. The modulation of GnIH synthesis and release by internal and environmental factors highlights the complex regulatory mechanisms underlying reproductive neuroendocrinology.
FRONTIERS IN NEUROENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Han-Tao Li, Dane C. Donegan, Daria Peleg-Raibstein, Denis Burdakov
Summary: This study explores a deep brain stimulation (DBS) strategy for modulating anxiety symptoms by targeting the lateral hypothalamus (LH). The researchers identify a DBS waveform that inhibits anxiety-related neural activity and suppresses anxiety behaviors in mouse models without any noticeable side effects. These findings suggest that acute hypothalamic DBS could be a potential strategy for managing treatment-resistant anxiety disorders.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Marion Georgelin, Vitor Hugo Bessa Ferreira, Fabien Cornilleau, Maryse Meurisse, Kevin Poissenot, Massimiliano Beltramo, Matthieu Keller, Lea Lansade, Hugues Dardente, Ludovic Calandreau
Summary: This study investigated the influence of photoperiod on learning, spatial orientation abilities, and emotional reactivity in male Japanese quail. It was found that quail under long photoperiod performed better in learning and spatial orientation tasks, while quail under short photoperiod displayed stronger emotional responses.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Mark Bohler, Alex Pauliukonis, Elizabeth R. Gilbert, Mark A. Cline
Summary: The study showed that centrally administered NPAF decreased food and water intake in quail, likely mediated by the melanocortin system in the hypothalamus.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2021)
Article
Neurosciences
Flavia Venetucci Gouveia, Mustansir Diwan, Raquel C. R. Martinez, Peter Giacobbe, Nir Lipsman, Clement Hamani
Summary: In this study, it is demonstrated that hypothalamic deep brain stimulation (pHyp-DBS) can reduce aggressive behavior in mice through modulation of testosterone and 5-HT1A mechanisms.
NEUROBIOLOGY OF DISEASE
(2023)
Article
Clinical Neurology
Clemens Neudorfer, Gavin J. B. Elias, Martin Jakobs, Alexandre Boutet, Jurgen Germann, Keshav Narang, Aaron Loh, Michelle Paff, Andreas Horn, Walter Kucharczyk, Wissam Deeb, Bryan Salvato, Leonardo Almeida, Kelly D. Foote, Paul B. Rosenberg, David F. Tang-Wai, William S. Anderson, Zoltan Mari, Francisco A. Ponce, David A. Wolk, Anna D. Burke, Stephen Salloway, Marwan N. Sabbagh, M. Mallar Chakravarty, Gwenn S. Smith, Constantine G. Lyketsos, Michael S. Okun, Andres M. Lozano
Summary: This study investigated the acute effects of hypothalamic region deep brain stimulation in patients with mild Alzheimer's disease, identifying various clinical responses and their neuroanatomical correlates. The findings localized the acute effects to specific tracts and nuclei within the hypothalamus and the wider diencephalon, providing insights for future neuromodulation research.
Article
Behavioral Sciences
Marjan Nikbakhtzadeh, Ghorbangol Ashabi, Mansoor Keshavarz, Esmail Riahi
Summary: This study demonstrates that high-frequency deep brain stimulation can prevent morphine-induced conditioned place preference in rats. Increasing the intensity of stimulation can completely block the preference, without affecting motor activity.
BEHAVIOURAL BRAIN RESEARCH
(2023)
Article
Physiology
Charlene Hanlon, Kayo Takeshima, Gregoy Y. Bedecarrats
Summary: Genetic selection for earlier sexual maturation and extended production cycles in laying hens has improved reproductive efficiency significantly. Changes in the control of the hypothalamic-pituitary gonadal axis have likely occurred, with sustained pituitary sensitivity to GnRH-I, recurrent elevations in FSH mRNA levels, and cyclical elevations in E-2 levels being key factors in sustaining extended laying periods.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Endocrinology & Metabolism
Somanshu Banerjee, Chandra Mohini Chaturvedi
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2015)
Article
Toxicology
Saba Shahin, Somanshu Banerjee, Surya Pal Singh, Chandra Mohini Chaturvedi
TOXICOLOGICAL SCIENCES
(2015)
Article
Biochemistry & Molecular Biology
Somanshu Banerjee, Chandra Mohini Chaturvedi
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2016)
Article
Biology
Somanshu Banerjee, Kazuyoshi Tsutsui, Chandra Mohini Chaturvedi
JOURNAL OF EXPERIMENTAL BIOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Somanshu Banerjee, Chandra Mohini Chaturvedi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2017)
Article
Geriatrics & Gerontology
Somanshu Banerjee, Saba Shahin, Chandra Mohini Chaturvedi
EXPERIMENTAL GERONTOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Somanshu Banerjee, Chandra Mohini Chaturvedi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Somanshu Banerjee, Chandra Mohini Chaturvedi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2018)
Article
Cell Biology
Somanshu Banerjee, Chandra Mohini Chaturvedi
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Review
Biochemistry & Molecular Biology
Laila Aryan, David Younessi, Michael Zargari, Somanshu Banerjee, Jacqueline Agopian, Shadie Rahman, Reza Borna, Gregoire Ruffenach, Soban Umar, Mansoureh Eghbali
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Cardiac & Cardiovascular Systems
John F. Park, Varina R. Clark, Somanshu Banerjee, Jason Hong, Asif Razee, Tiffany Williams, Gregory Fishbein, Lou Saddic, Soban Umar
Summary: RV failure in monocrotaline and Sugen with hypoxia models showed similar gene expressions and biological pathways, with significant enrichment in genes related to epithelial-to-mesenchymal transition, inflammation, and metabolism. Human RV tissue from PAH-induced RV failure patients exhibited notable fibrosis, endothelial-to-mesenchymal transition, and elevated expression of cellular communication network factor 2 in perivascular areas compared to normal RV.
CIRCULATION-HEART FAILURE
(2021)
Review
Cardiac & Cardiovascular Systems
John F. Park, Somanshu Banerjee, Soban Umar
PULMONARY CIRCULATION
(2020)
Article
Medicine, Research & Experimental
Rashmi Shukla, Nidhi Pandey, Somanshu Banerjee, Yamini B. Tripathi
BIOMEDICINE & PHARMACOTHERAPY
(2017)
Article
Biochemistry & Molecular Biology
Girgis Obaid, Menitte Eroy, Jie Zhao, Shazia Bano, Mari Mino-Kenudson, Tayyaba Hasan
Summary: The presence of desmoplasia in pancreatic ductal adenocarcinoma (PDAC) is associated with poor treatment outcomes and reduced drug delivery. By analyzing collagen subtypes in PDAC tumors following different treatment regimens, immunofluorescence profiling can predict long-term survival and tumor growth inhibition. This information can aid in personalized treatment and improve patient survival.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Fatemeh Malekpour, Rashin Bahrami, Mahshid Hodjat, Neda Hakimiha, Behnam Bolhari, Aidin Sooratgar, Soheil Niavarzi
Summary: This study investigated the effect of photobiomodulation (PBM) therapy using an 808 nm diode laser on cellular modulation mechanisms in regenerative endodontic procedures (REPs). The results showed that PBM treatment significantly increased cell viability and migration, and enhanced the release of TGF-131 from dentin.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Pranathi Tata, Ramakrishnan Ganesan, Jayati Ray Dutta
Summary: Thin film coatings with potent antibacterial properties are widely used in medical devices, frequently touched surfaces, and food packaging. However, achieving antibacterial performance under both light and dark conditions remains a challenge. In this study, we successfully prepared AgBr-coated ZnO nanorod thin film architecture using a unique surfactant-mediated solution-phase spin-coating approach. The resulting structures showed dual functionality as antimicrobial agents and photosensitizers, effectively enhancing the visible-light photodisinfection efficacy of ZnO nanorods. The concentration of the surfactant-based precursor solution could be modulated to control the AgBr content. Additionally, components like urea and lactic acid were found to enhance the photocatalytic efficiency of the structures.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)