Article
Pediatrics
Bahar Ashjaei, Afshar Ghamari Khameneh, Neda Pak, Gisoo Darban Hosseini Amirkhiz, Alipasha Meysamie, Moeinadin Safavi, Sanam Darban Hosseini Amirkhiz, Parin Tanzi
Summary: According to the study findings, it is safe to perform single stage TERPT when the aganglionic length on CE is less than 52 cm and the child with Hirschsprung disease is older than 10 months. These patients have a low chance of requiring additional surgeries.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Pediatrics
Yanan Zhang, Zhaozhou Liu, Shuangshuang Li, Shen Yang, Jiawei Zhao, Ting Yang, Siqi Li, Yongwei Chen, Weihong Guo, Dawei Hou, Yingzi Li, Jinshi Huang
Summary: This study evaluated the safety and efficacy of transanal endorectal pull-through (TEPT) surgery in newborns with Hirschsprung disease, and assessed the short-term and long-term outcomes after surgery through long-term follow-up. The results showed that TEPT surgery is effective and safe in newborns, with a low rate of postoperative complications.
PEDIATRIC SURGERY INTERNATIONAL
(2022)
Article
Pediatrics
Zhaozhou Liu, Yanan Zhang, Shuangshuang Li, Jiawei Zhao, Ting Yang, Jinshi Huang
Summary: This study aimed to assess the long-term outcomes of neonatal patients with Hirschsprung disease (HD) after single-stage transanal endorectal pull-through (TEPT) and explore predictive factors for subnormal bowel function. The results showed that most HD patients who underwent one-stage TEPT in the neonatal period had favorable long-term results, and the levels of aganglionosis with long-segment or TCA and long postoperative hospital stays may be closely related to subnormal bowel function.
PEDIATRIC SURGERY INTERNATIONAL
(2023)
Article
Gastroenterology & Hepatology
Gunadi, Gabriele Ivana, Desyifa Annisa Mursalin, Ririd Tri Pitaka, Muhammad Wildan Zain, Dyah Ayu Puspitarani, Dwiki Afandy, Susan Simanjaya, Andi Dwihantoro, Akhmad Makhmudi
Summary: TEPT is a preferable treatment method for HSCR due to its less invasiveness and lower morbidity. The functional outcomes in HSCR patients after TEPT are relatively good, with factors such as sex, age at TEPT performed, and post-operative complications affecting bowel movement, soiling, and constipation risks. Further multicenter studies with larger sample sizes are needed to confirm these findings.
BMC GASTROENTEROLOGY
(2021)
Article
Pediatrics
Gunadi, Raedi Ardlo Luzman, Sagita Mega Sekar Kencana, Bhagas Dwi Arthana, Fauzan Ahmad, Ganjar Sulaksmono, Agitha Swandaru Rastaputra, Golda Puspa Arini, Ririd Tri Pitaka, Andi Dwihantoro, Akhmad Makhmudi
Summary: This study compared the HAEC frequency after TEPT using two different cut-off values of the scoring system and suggested further expanding the diagnosis of HAEC by using a cut-off of ≥4. Additionally, it demonstrated for the first time that hemoglobin level is a strong risk factor for HAEC development after TEPT.
FRONTIERS IN PEDIATRICS
(2021)
Article
Pediatrics
Lieke Beltman, Danielle Roorda, Manouk Backes, Jaap Oosterlaan, L. W. Ernest van Heurn, Joep P. M. Derikx
Summary: This study retrospectively analyzed data of children with Hirschsprung disease who underwent transanal endorectal pull-through (TERPT) between 2005 and 2020. The study aimed to determine the prevalence and severity of postoperative complications within 30 days after TERPT and identify risk factors for short-term complications. The results showed a complication rate of 21%, with anastomotic complications being the most common. Postoperative rectal irrigation may be the cause of lethal perforations.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Article
Pediatrics
Noemi Cantone, Vincenzo Davide Catania, Andrea Zulli, Eduje Thomas, Elisa Severi, Tocchioni Francesca, Centonze Nicola, Ciardini Enrico, Noccioli Bruno, Libri Michele, Gargano Tommaso, Lima Mario
Summary: This study compared two different minimally invasive surgical techniques for Hirschsprung disease and found that both TERPT and LA-TERPT are safe and feasible. TERPT patients have faster postoperative recovery while LA-TERPT patients have a slightly lower incidence of complications. Long-term functional outcomes are similar between the two groups.
PEDIATRIC SURGERY INTERNATIONAL
(2023)
Article
Surgery
Soo-Hong Kim, Yong-Hoon Cho, Hae-Young Kim
Summary: The functional outcomes of TERPT performed during the infantile period are similar to the normal population, with uncomfortable symptoms diminishing and functions improving with age in most cases.
ANNALS OF SURGICAL TREATMENT AND RESEARCH
(2021)
Review
Medicine, General & Internal
Qi Wang, Yuanyuan Liang, Mengqi Luo, Liwei Feng, Bo Xiang
Summary: This study compared the effectiveness of the Duhamel and TERPT procedures in treating children with Hirschsprung's disease. The results showed that compared to the TERPT procedure, the Duhamel procedure had a longer postoperative hospital stay, a higher incidence of postoperative constipation, and a lower incidence of postoperative anastomotic stricture. However, the effect of these procedures on operation time and the incidence of postoperative enterocolitis remains unclear.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Remi Andre Karlsen, Anders Telle Hoel, Marianne Valeberg Fosby, Kjetil Ertresvag, Astrid Ingeborg Austrheim, Kjetil Juul Stensrud, Kristin Bjornland
Summary: There was no difference in long-term bowel function in patients with rectosigmoid Hirschsprung's disease operated with TERPT or LERPT. However, more LERPT patients required unplanned procedures under general anesthesia.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Article
Pediatrics
Zachary J. Kastenberg, Mark A. Taylor, Megan M. Durham, Casey M. Calkins, Rebecca M. Rentea, Richard J. Wood, Jeffrey R. Avansino, Marc A. Levitt, Kathleen D. van Leeuwen, Katelyn E. Lewis, Ron W. Reeder, Michael D. Rollins
Summary: The study investigated the impact of endorectal pull-through for Hirschsprung disease, finding that delayed surgery offers a safe alternative with at least equivalent functional outcomes compared to neonatal repair.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Medicine, General & Internal
Vanesa Villamil, Juana Maria Sanchez Morote, Maria Josefa Aranda Garcia, Ramon Ruiz Pruneda, Maria Fernandez Ibieta
Summary: Complications of surgery for Hirschsprung's disease include general complications of abdominal surgery and specific complications such as obstruction. We report a case of a 4-month-old baby with Hirschsprung's disease who developed postoperative constipation due to unusual folding of the muscular cuff, which narrowed the colon. Laparoscopic surgery was performed to confirm the diagnosis and visualize the rectal cuff.
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
(2022)
Article
Pediatrics
Chunlei Jiao, Didi Zhuansun, Ying He, Pei Wang, Dandan Li, Jiexiong Feng, Donghai Yu
Summary: This study retrospectively analyzed the cases of anastomotic leakage in 12 children after radical surgery for HSCR. It was found that the incidence of anastomotic leakage was low. For patients with anastomotic leakage, enterostomy should be performed in a timely manner and redo pull-through surgery should be conducted in cases of anastomotic fistula or stricture.
PEDIATRIC SURGERY INTERNATIONAL
(2022)
Article
Pediatrics
Maggie L. Westfal, Ongoly Okiemy, Patrick Ho Yu Chung, Jiexiong Feng, Changgui Lu, Miyano Go, Paul Kwong Hang Tam, Weibing Tang, Kenneth Kak Yuen Wong, Atsuyuki Yamataka, Richard A. Guyer, Daniel P. Doody, Allan M. Goldstein
Summary: The study suggests that infants undergoing endorectal pull-through at age <2.5 months may have worse functional outcomes, including higher rates of soiling, anastomotic stricture, and anastomotic leak.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Review
Pediatrics
Ulgen Celtik, Idil Yavuz, Orkan Ergun
Summary: This meta-analysis compares the long-term results between transanal endorectal pull-through (TEPT) and transabdominal (TAB) pull-through in the surgical management of Hirschsprung's disease. The study finds that TEPT is superior to TAB in terms of constipation and enterocolitis, and there is no statistical difference in postoperative incontinence rates. However, further research on long-term LTEPT results is needed for more reliable conclusions.
PEDIATRIC SURGERY INTERNATIONAL
(2023)