Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Targeting the cancer epigenome for therapy

(2016) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Myopodin methylation is a prognostic biomarker and predicts antiangiogenic response in advanced kidney cancer

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Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways

(2016) Biao Ma et al.   Nature Communications

An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression

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Eradicating tumor drug resistance at its YAP-biomechanical roots

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YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins

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Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma

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Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells

(2015) Upal Basu-Roy et al.   Nature Communications

Suppression of Early Hematogenous Dissemination of Human Breast Cancer Cells to Bone Marrow by Retinoic Acid-Induced 2

(2015) S. Werner et al.   Cancer Discovery

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology

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Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

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RASAL2 activates RAC1 to promote triple-negative breast cancer progression

(2014) Min Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

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GSTP1 expression predicts poor pathological complete response to neoadjuvant chemotherapy in ER-negative breast cancer

(2012) Tomohiro Miyake et al.   CANCER SCIENCE

The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites

(2012) Hua Gao et al.   CELL

Diagnostic and prognostic utility of methylation and protein expression patterns of myopodin in colon cancer

(2012) Sergio Esteban et al.   TUMOR BIOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

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The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

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Tumor Metastasis: Molecular Insights and Evolving Paradigms

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DNA methylation profiling reveals a predominant immune component in breast cancers

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The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

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A Perspective on Cancer Cell Metastasis

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A gene expression signature identifies two prognostic subgroups of basal breast cancer

(2010) Renaud Sabatier et al.   BREAST CANCER RESEARCH AND TREATMENT

Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

(2010) Daniel P. Silver et al.   JOURNAL OF CLINICAL ONCOLOGY

Classical Cyclophosphamide, Methotrexate, and Fluorouracil Chemotherapy Is More Effective in Triple-Negative, Node-Negative Breast Cancer: Results From Two Randomized Trials of Adjuvant Chemoendocrine Therapy for Node-Negative Breast Cancer

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Triple-negative breast cancer: disease entity or title of convenience?

(2010) Lisa Carey et al.   Nature Reviews Clinical Oncology

Triple-Negative Breast Cancer

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An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

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Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer

(2008) Nancy U. Lin et al.   CANCER

Breast Cancer Subtype Approximated by Estrogen Receptor, Progesterone Receptor, and HER-2 Is Associated With Local and Distant Recurrence After Breast-Conserving Therapy

(2008) Paul L. Nguyen et al.   JOURNAL OF CLINICAL ONCOLOGY

Refinement of breast cancer classification by molecular characterization of histological special types

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Discovery of myopodin methylation in bladder cancer

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TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS