Calcium signaling of in situ chondrocytes in articular cartilage under compressive loading: Roles of calcium sources and cell membrane ion channels

Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

(2017) M Rocio Servin-Vences et al.   eLife

Osteoarthritis year in review 2015: mechanics

(2016) N.H. Varady et al.   OSTEOARTHRITIS AND CARTILAGE

Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain

(2016) Patrick Kanju et al.   Scientific Reports

A mutation inTRPV4results in altered chondrocyte calcium signaling in severe metatropic dysplasia

(2015) Lauren Hurd et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The effect of chemically defined medium on spontaneous calcium signaling of in situ chondrocytes during long-term culture

(2015) Yilu Zhou et al.   JOURNAL OF BIOMECHANICS

Inhibition of T-Type Voltage Sensitive Calcium Channel Reduces Load-Induced OA in Mice and Suppresses the Catabolic Effect of Bone Mechanical Stress on Chondrocytes

(2015) Padma P. Srinivasan et al.   PLoS One

The effect of compressive loading magnitude on in situ chondrocyte calcium signaling

(2014) Ryan M. J. Madden et al.   Biomechanics and Modeling in Mechanobiology

Biomechanics and mechanobiology in functional tissue engineering

(2014) Farshid Guilak et al.   JOURNAL OF BIOMECHANICS

Role of Interstitial Fluid Pressurization in TMJ Lubrication

(2014) B.K. Zimmerman et al.   JOURNAL OF DENTAL RESEARCH

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

(2014) Whasil Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

(2014) C. J. O'Conor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes

(2014) Yue Gao et al.   Biomed Research International

Micromechanical mapping of early osteoarthritic changes in the pericellular matrix of human articular cartilage

(2013) R.E. Wilusz et al.   OSTEOARTHRITIS AND CARTILAGE

Calcium response in osteocytic networks under steady and oscillatory fluid flow

(2012) X. Lucas Lu et al.   BONE

Chondrocyte deformation under extreme tissue strain in two regions of the rabbit knee joint

(2012) Ryan Madden et al.   JOURNAL OF BIOMECHANICS

Mechanically induced calcium signaling in chondrocytes in situ

(2012) Sang-Kuy Han et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow

(2011) X Lucas Lu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation

(2010) Bo Huo et al.   CELL CALCIUM

Intercellular calcium wave propagation in linear and circuit-like bone cell networks

(2010) B. Huo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Effects of Dexamethasone on the Functional Properties of Cartilage Explants during Long-Term Culture

(2009) Bian Liming et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

(2009) Mimi N. Phan et al.   ARTHRITIS AND RHEUMATISM

Depth-dependent analysis of the role of collagen fibrils, fixed charges and fluid in the pericellular matrix of articular cartilage on chondrocyte mechanics

(2008) Rami K Korhonen et al.   JOURNAL OF BIOMECHANICS

Signal transduction in electrically stimulated articular chondrocytes involves translocation of extracellular calcium through voltage-gated channels

(2008) J. Xu et al.   OSTEOARTHRITIS AND CARTILAGE

Control of chondrocyte regulatory volume decrease (RVD) by [Ca2+]i and cell shape

(2007) M.J.P. Kerrigan et al.   OSTEOARTHRITIS AND CARTILAGE