期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 24, 页码 13609-13616出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b02113
关键词
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资金
- National Program on Key Research Project [2016YFA0602900]
- National Natural Science Foundation of China [21420102003, 21662002, 21602031]
- Pearl River SAMP
- T Nova Program of Guangzhou [201610010160]
- Advanced Innovation Research Teams Project of Jiangxi Province [20133BCB24011]
- Jiangxi Natural Science Foundation [20151BAB203011, 20171BAB203010]
A base-mediated three-component tandem reaction for the synthesis of multisubstituted pyrimidines from amidines, aryl alkynes, and aldehydes in a one-pot manner has been developed. Advantages of this transformation include being transition-metal free, high efficiency, available starting materials, and being environmentally friendly.
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