期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 19, 页码 10043-10050出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01510
关键词
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资金
- National Natural Science Foundation of China [21502042, 51403051, 21477033, 21204018]
- Henan Provincial Education Department [15A150041, 16A150003]
A simple and efficient method for the base mediated synthesis of unsymmetrical 1,3,5-triazin-2-amines has been developed. The protocol uses readily available imidates, guanidines, and amides or aldehydes as the starting materials, cesium carbonate as the base, no catalyst or additive is required, and the three-component reaction provides diverse 1,3,5-triazin-2-amines in moderate to good yields with tolerance of wide functional groups.
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