4.6 Article

Shear-rate-dependent rheology effects on mass transport and surface reactions in biomicrofluidic devices

期刊

AICHE JOURNAL
卷 61, 期 6, 页码 1912-1924

出版社

WILEY
DOI: 10.1002/aic.14781

关键词

electroosmotic flow; microfluidics; mass transport; surface reaction; nonNewtonian fluids

资金

  1. Iran's National Elites Foundation (INEF)

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Consideration is given to shear-rate-dependent rheology effects on mass transport in a heterogeneous microreactor of rectangular cross section, utilizing both numerical and analytical approaches. The carrier liquid obeys the power-law viscosity model and is actuated primarily by an electrokinetic pumping mechanism. It is discovered that, considering the shear-thinning biofluids to be Newtonian fluids gives rise to an overestimation of the saturation time. The degree of overestimation is higher in the presence of large Damkohler numbers and electric double layer thicknesses. It is also increased by the application of a favorable pressure gradient, whereas the opposite is true when an opposed pressure gradient is applied. In addition, a channel of square cross section corresponds to the maximum fluid rheology effects. Finally, the numerical results indicate the existence of a concentration wave when using long channels. This is confirmed by analytical solutions, providing a closed form solution for wave propagation speed. (c) 2015 American Institute of Chemical Engineers AIChE J, 61: 1912-1924, 2015

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