期刊
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
卷 41, 期 -, 页码 1-11出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jnutbio.2016.06.001
关键词
Human milk; Breast milk; Protein; Lactation; Infant nutrition; Amino acids
资金
- Nestle Nutrition
The protein content of breast milk provides a foundation for estimating protein requirements of infants. Because it serves as a guideline for regulatory agencies issuing regulations for infant formula composition, it is critical that information on the protein content of breast milk is reliable. We have therefore carried out a meta-analysis of the protein and amino acid contents of breast milk and how they evolve during lactation. As several bioactive proteins are not completely digested in the infant and therefore represent non-utilizable protein, we evaluated the quantity, mechanism of action and digestive fate of several major breast milk proteins. A better knowledge of the development of the protein contents of breast milk and to what extent protein utilization changes with age of the infant will help improve understanding of protein needs in infancy. It is also essential when designing the composition of infant formulas, particularly when the formula uses a staging approach in which the composition of the formula is modified in stages to reflect changes in breast milk and changing requirements as the infant ages. (C) 2016 The Authors. Published by Elsevier Inc.
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