Safe long-term repeated disruption of the blood-brain barrier using an implantable ultrasound device: a multiparametric study in a primate model

Focused Ultrasound Microbubble Destruction-Mediated Changes in Blood-Brain Barrier Permeability Assessed by Contrast-Enhanced Magnetic Resonance Imaging

(2017) Feng Wang et al.   JOURNAL OF ULTRASOUND IN MEDICINE

Enhanced brain distribution of carboplatin in a primate model after blood–brain barrier disruption using an implantable ultrasound device

(2015) Lauriane Goldwirt et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Long-Term Safety of Repeated Blood-Brain Barrier Opening via Focused Ultrasound with Microbubbles in Non-Human Primates Performing a Cognitive Task

(2015) Matthew E. Downs et al.   PLoS One

Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

(2014) Pengfei Jiang et al.   Journal of Translational Medicine

Phase I Study of GRN1005 in Recurrent Malignant Glioma

(2013) J. Drappatz et al.   CLINICAL CANCER RESEARCH

Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood–tumor and blood–brain barriers improve outcomes in a rat glioma model

(2013) Muna Aryal et al.   JOURNAL OF CONTROLLED RELEASE

Opening of the blood-brain barrier with an unfocused ultrasound device in rabbits

(2013) Kevin Beccaria et al.   JOURNAL OF NEUROSURGERY

Fast in vivo imaging of amyloid plaques using μ-MRI Gd-staining combined with ultrasound-induced blood–brain barrier opening

(2013) Mathieu D. Santin et al.   NEUROIMAGE

Temporary Disruption of the Blood-Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

(2012) N. McDannold et al.   CANCER RESEARCH

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

(2012) Uwe Heinemann et al.   GLIA

The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound

(2012) Juyoung Park et al.   JOURNAL OF CONTROLLED RELEASE

Improved Anti-Tumor Effect of Liposomal Doxorubicin After Targeted Blood-Brain Barrier Disruption by MRI-Guided Focused Ultrasound in Rat Glioma

(2012) Lisa H. Treat et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

A phase I trial of carboplatin administered by convection-enhanced delivery to patients with recurrent/progressive glioblastoma multiforme

(2011) Edward White et al.   Contemporary Clinical Trials

Noninvasive, Transient and Selective Blood-Brain Barrier Opening in Non-Human Primates In Vivo

(2011) Fabrice Marquet et al.   PLoS One

The impact of standing wave effects on transcranial focused ultrasound disruption of the blood–brain barrier in a rat model

(2010) Meaghan A O'Reilly et al.   PHYSICS IN MEDICINE AND BIOLOGY

Progress and problems in the application of focused ultrasound for blood–brain barrier disruption

(2008) Natalia Vykhodtseva et al.   ULTRASONICS

Blood-Brain Barrier Disruption Induced by Focused Ultrasound and Circulating Preformed Microbubbles Appears to Be Characterized by the Mechanical Index

(2008) Nathan McDannold et al.   ULTRASOUND IN MEDICINE AND BIOLOGY