HMGB1: a novel protein that induced platelets active and aggregation via Toll-like receptor-4, NF-κB and cGMP dependent mechanisms

Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein

(2014) Le-Xing Yu et al.   Nature Communications

HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4

(2013) Jean-Marc Tadie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The activation of HMGB1 as a progression factor on inflammation response in normal human bronchial epithelial cells through RAGE/JNK/NF-κB pathway

(2013) Xiaojin Wu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction

(2012) Tousei Hashimoto et al.   ATHEROSCLEROSIS

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

A novel role of andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: the pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP

(2011) Wan-Jung Lu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Novel roles of cAMP/cGMP-dependent signaling in platelets

(2011) A. SMOLENSKI   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Toll-like receptor 4 signal transduction in platelets: novel pathways

(2010) Julien Berthet et al.   BRITISH JOURNAL OF HAEMATOLOGY

Advanced glycation end products strongly activate platelets

(2009) Thomas Gawlowski et al.   EUROPEAN JOURNAL OF NUTRITION

NF-κB inhibitors impair platelet activation responses

(2009) E. MALAVER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes

(2009) Lea M. Beaulieu et al.   THROMBOSIS RESEARCH

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)

(2008) Judy R. van Beijnum et al.   ANGIOGENESIS

Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling

(2007) J. S. Isenberg et al.   BLOOD