Article
Oncology
Jianxiong Fu, Jing Ye, Wenrong Zhu, Jingtao Wu, Wenxin Chen, Qingqiang Zhu
Summary: Diffusion kurtosis imaging (DKI) can serve as another noninvasive biomarker for the differential diagnosis of benign and malignant renal tumors. By comparing the values of MD, MK, KA, and RK, different types of renal tumors can be effectively distinguished.
Article
Biochemical Research Methods
Akanksha Bhargava, Benjamin Monteagudo, Priyanka Kushwaha, Janaka Senarathna, Yunke Ren, Ryan C. Riddle, Manisha Aggarwal, Arvind P. Pathak
Summary: VascuViz is a versatile workflow for multimodal imaging of the vasculature, which allows simultaneous 3D imaging using magnetic resonance imaging, computed tomography, and optical microscopy. Its ease of use and compatibility with different tissue types make VascuViz a valuable tool for image-based vascular systems biology.
Article
Radiology, Nuclear Medicine & Medical Imaging
Haiying Zhou, Jianguang Zhang, Xiao Ming Zhang, Tianwu Chen, Jiani Hu, Zonglin Jing, Shunhai Jian
Summary: The study found that renal diffusion kurtosis imaging is valuable for the diagnosis of early diabetic nephropathy, with mean kurtosis values serving as a more sensitive biomarker than mean diffusivity values. The MR DKI technique may be noninvasive and effective in detecting early DN.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yiqi Hu, Qilan Hu, Chenao Zhan, Ting Yin, Tao Ai
Summary: This study investigated the intraobserver and interobserver reproducibility of diffusion-weighted imaging (DWI) measurements, diffusion-kurtosis imaging (DKI) parameters, and image quality evaluation in breast lesions between single-shot echo-planar imaging (ss-EPI) and readout-segmented echo-planar imaging (rs-EPI). The results showed that compared to ss-EPI, rs-EPI had higher intraobserver and interobserver reproducibility for quantitative diffusion-related parameters and image quality assessments.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Neurosciences
Johann M. E. Jende, Zoltan Kender, Christoph Mooshage, Jan B. Groener, Lucia Alvarez-Ramos, Jennifer Kollmer, Alexander Juerchott, Artur Hahn, Sabine Heiland, Peter Nawroth, Martin Bendszus, Stefan Kopf, Felix T. Kurz
Summary: The study shows that the sciatic nerve's fractional anisotropy is a surrogate marker for functional and electrophysiological parameters of both upper and lower limbs in patients with diabetes and prediabetes, suggesting that nerve damage in these patients affects the entire peripheral nervous system rather than being limited to symptomatic limbs.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Hong Zhang, Wen-Jie He, Li-Hong Liang, Han-Wen Zhang, Xie-Jun Zhang, Liang Zeng, Si-Ping Luo, Fan Lin, Yi Lei
Summary: In this study, DSI was used to measure diffusion parameters of corticospinal tracts in iNPH patients compared to healthy controls. Results showed lower QA and ISO values, and higher MD, AD, and RD values in iNPH patients, with no significant differences in GFA and FA values. This quantitative evaluation using DSI could enhance understanding of the disease mechanism.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Yeji Moon, Jin-Ju Yang, Won June Lee, Ji Young Lee, Yu Jeong Kim, Han Woong Lim
Summary: This study quantitatively investigated the microstructural properties of the optic nerve in an elderly population using dMRI tractography, revealing a negative correlation between FA and age. Females exhibited significantly higher FA than males.
FRONTIERS IN NEUROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Konrad A. Kruk, Tobias J. Dietrich, Simon Wildermuth, Sebastian Leschka, Andreas Toepfer, Stephan Waelti, Chan-Hi Olaf Kim, Sabine Guesewell, Tim Fischer
Summary: This study evaluated the feasibility of diffusion-weighted imaging (DWI) in diagnosing osteomyelitis and bone marrow edema in the forefoot. The measurement of apparent diffusion coefficient (ADC) values allowed for differentiation between healthy and abnormal bone and provided specific cutoff values for the confirmation or exclusion of osteomyelitis.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stefania Montemezzi, Giuseppe Cardano, Silvia Storer, Nicolo Cardobi, Carlo Cavedon, Lucia Camera
Summary: This study demonstrates the feasibility and efficacy of using DWI in MRI-guided breast biopsies for accurate lesion targeting and device positioning. DWI can effectively detect both mass and non-mass lesions with a minimum size of 5 mm.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huan Yang, Peng Lv, Ranying Zhang, Caixia Fu, Jiang Lin
Summary: The study found that low b-value DWI has significant advantages in detecting inflamed vessels in active Takayasu arteritis, with higher image quality and blood suppression compared to T2-weighted imaging. Additionally, the signal-to-noise ratio and contrast-to-noise ratio of the diseased vessel walls were significantly higher on DWI compared to T2WI.
EUROPEAN RADIOLOGY
(2021)
Article
Neurosciences
Kevin Grant Solar, Sarah Treit, Christian Beaulieu
Summary: The study used high resolution DTI to investigate diffusion and volume changes in the hippocampus of healthy volunteers, finding age-related differences in different regions of the hippocampus. Correlations between memory, FA, and volume were significant in younger subjects but not in older age groups.
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexander Rau, Pia M. Jungmann, Thierno D. Diallo, Marco Reisert, Elias Kellner, Michel Eisenblaetter, Fabian Bamberg, Matthias Jung
Summary: Quantitative MRI techniques, such as diffusion microstructure imaging (DMI), can provide additional information about muscular function and microstructure, potentially serving as a potential biomarker for young athletes.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Pietro Valerio Foti, Mario Travali, Renato Farina, Stefano Palmucci, Corrado Spatola, Luigi Raffaele, Vincenzo Salamone, Rosario Caltabiano, Giuseppe Broggi, Lidia Puzzo, Andrea Russo, Michele Reibaldi, Antonio Longo, Paolo Vigneri, Teresio Avitabile, Giovani Carlo Ettorre, Antonio Basile
Summary: Uveal melanoma is a malignant tumor originating from pigmented melanocytes, with prognosis related to histopathologic and genetic features, tumor size and location. MRI plays a key role in diagnosis and treatment planning, mainly depending on melanin content for tumor visualization. Radiologists and MRI are significant in the clinical management of uveal melanoma.
INSIGHTS INTO IMAGING
(2021)
Article
Mathematics, Applied
Shuhong Wang, Yingjie Liang, Richard L. Magin
Summary: This article discusses the application of diffusion-weighted magnetic resonance imaging in describing the structure of biological tissues, as well as the analysis and fitting of experimental data using the VDC model. The experimental results show that the VDC model can effectively capture the characteristics of signal attenuation, and the ultraslow diffusion model provides the best fit for diffusion in the optic nerve.
COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nan Meng, Xuejia Wang, Jing Sun, Dongming Han, Yan Bai, Wei Wei, Zhe Wang, Fei Jia, Kaiyu Wang, Meiyun Wang
Summary: DKI is superior to APTWI in differentiating between benign and malignant breast lesions. Each parameter is correlated with some prognostic factors to a certain extent.
EUROPEAN RADIOLOGY
(2021)
Article
Psychology, Developmental
David Pagliaccio, Jiook Cha, Xiaofu He, Marilyn Cyr, Paula Yanes-Lukin, Pablo Goldberg, Martine Fontaine, Moira A. Rynn, Rachel Marsh
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2020)
Article
Biochemistry & Molecular Biology
Emily L. Dennis, Seth G. Disner, Negar Fani, Lauren E. Salminen, Mark Logue, Emily K. Clarke, Courtney C. Haswell, Christopher L. Averill, Lee A. Baugh, Jessica Bomyea, Steven E. Bruce, Jiook Cha, Kyle Choi, Nicholas D. Davenport, Maria Densmore, Stefan du Plessis, Gina L. Forster, Jessie L. Frijling, Atilla Gonenc, Staci Gruber, Daniel W. Grupe, Jeffrey P. Guenette, Jasmeet Hayes, David Hofmann, Jonathan Ipser, Tanja Jovanovic, Sinead Kelly, Mitzy Kennis, Philipp Kinzel, Saskia B. J. Koch, Inga Koerte, Sheri Koopowitz, Mayuresh Korgaonkar, John Krystal, Lauren A. M. Lebois, Gen Li, Vincent A. Magnotta, Antje Manthey, Geoff J. May, Deleene S. Menefee, Laura Nawijn, Steven M. Nelson, Richard W. J. Neufeld, Jack B. Nitschke, Daniel O'Doherty, Matthew Peverill, Kerry J. Ressler, Annerine Roos, Margaret A. Sheridan, Anika Sierk, Alan Simmons, Raluca M. Simons, Jeffrey S. Simons, Jennifer Stevens, Benjamin Suarez-Jimenez, Danielle R. Sullivan, Jean Theberge, Jana K. Tran, Leigh van den Heuvel, Steven J. A. van der Werff, Sanne J. H. van Rooij, Mirjam van Zuiden, Carmen Velez, Mieke Verfaellie, Robert R. J. M. Vermeiren, Benjamin S. C. Wade, Tor Wager, Henrik Walter, Sherry Winternitz, Jonathan Wolff, Gerald York, Ye Zhu, Xi Zhu, Chadi G. Abdallah, Richard Bryant, Judith K. Daniels, Richard J. Davidson, Kelene A. Fercho, Carol Franz, Elbert Geuze, Evan M. Gordon, Milissa L. Kaufman, William S. Kremen, Jim Lagopoulos, Ruth A. Lanius, Michael J. Lyons, Stephen R. McCauley, Regina McGlinchey, Katie A. McLaughlin, William Milberg, Yuval Neria, Miranda Olff, Soraya Seedat, Martha Shenton, Scott R. Sponheim, Dan J. Stein, Murray B. Stein, Thomas Straube, David F. Tate, Nic J. A. van der Wee, Dick J. Veltman, Li Wang, Elisabeth A. Wilde, Paul M. Thompson, Peter Kochunov, Neda Jahanshad, Rajendra A. Morey
Summary: Research suggests that PTSD may be associated with disrupted white matter organization, especially in the tapetum region, which is connected to the hippocampus network consistently implicated in PTSD.
MOLECULAR PSYCHIATRY
(2021)
Article
Neurosciences
Eyal Abraham, Jonathan Posner, Priya J. Wickramaratne, Natalie Aw, Milenna T. van Dijk, Jiook Cha, Myrna M. Weissman, Ardesheer Talati
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2020)
Article
Neurosciences
Alex Luna, Joel Bernanke, Kakyeong Kim, Natalie Aw, Jordan D. Dworkin, Jiook Cha, Jonathan Posner
Summary: The study compared brain predicted age difference in youth using multimodal MRI and stacked ensemble machine learning. Results showed that combining morphometry and connectomes in the model had better performance, serving as a clinically relevant indicator of psychiatric and cognitive functioning in youth.
HUMAN BRAIN MAPPING
(2021)
Article
Psychology, Developmental
Brennan H. Baker, Yoonjung Yoonie Joo, Junghoon Park, Jiook Cha, Andrea A. Baccarelli, Jonathan Posner
Summary: This study found an association between young maternal age and increased risk for child ADHD. Socioeconomic disadvantages were likely the primary explanation for this association, although genetics and environmental factors also played a role.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Meeting Abstract
Neurosciences
Milenna van Dijk, Olivia Olmo, Irina Pokhvisneva, Sachin Patel, Jiook Cha, Marc Gameroff, Jonathan Posner, Michael J. Meaney, Myrna Weissman, Patricia Silveira, Ardesheer Talati
NEUROPSYCHOPHARMACOLOGY
(2021)
Meeting Abstract
Neurosciences
Holly Hunsberger, Lee Seonjoo, Jiook Cha, Alicia Whye, Christine Ann Denny
NEUROPSYCHOPHARMACOLOGY
(2021)
Meeting Abstract
Neurosciences
Seo-Yoon Moon, Hee-Hwan Wang, Hyun-Jin Kim, KaKyeong Kim, Eun-Ji Lee, Woo-Young Ahn, Yoonjung Yoonie Joo, Jiook Cha
NEUROPSYCHOPHARMACOLOGY
(2021)
Meeting Abstract
Neurosciences
Milenna van Dijk, Rushell Dixon, Yun Wang, Jiook Cha, Eyal Abraham, Marc Gameroff, Nora Kelsall, Christoph Anacker, Jonathan Posner, Myrna Weissman, Ardesheer Talati
NEUROPSYCHOPHARMACOLOGY
(2020)
Meeting Abstract
Neurosciences
Milenna van Dijk, Christoph Anacker, Jiook Cha, Yun Wang, Eyal Abraham, Nora Kelsall, Jonathan Posner, Myrna M. Weissman, Ardesheer Talati
BIOLOGICAL PSYCHIATRY
(2020)
Meeting Abstract
Neurosciences
Eyal Abraham, Myrna Weissman, Priya Wickramaratne, Milenna van Dijk, Lifang Pan, Marc Gameroff, Yun Wang, Jiook Cha, Jonathan Posner, Ardesheer Talati
BIOLOGICAL PSYCHIATRY
(2020)
Article
Endocrinology & Metabolism
Claudia Lugo-Candelas, Yajing Pang, Seonjoo Lee, Jiook Cha, Susie Hong, Lisa Ranzenhofer, Rachel Korn, Haley Davis, Hailey McInerny, Janet Schebendach, Wendy K. Chung, Rudolph L. Leibel, B. Timothy Walsh, Jonathan Posner, Michael Rosenbaum, Laurel Mayer
OBESITY SCIENCE & PRACTICE
(2020)
Article
Health Care Sciences & Services
Ji Hwan Park, Han Eol Cho, Jong Hun Kim, Melanie M. Wall, Yaakov Stern, Hyunsun Lim, Shinjae Yoo, Hyoung Seop Kim, Jiook Cha
NPJ DIGITAL MEDICINE
(2020)
Meeting Abstract
Neurosciences
Milenna van Dijk, Jiook Cha, David Semanek, Jonathan Posner, Ardesheer Talati, Myrna Weissman
NEUROPSYCHOPHARMACOLOGY
(2019)
Article
Neuroimaging
Yun Wang, Chenxiao Xu, Ji-Hwan Park, Seonjoo Lee, Yaakov Stern, Shinjae Yoo, Jong Hun Kim, Hyoung Seop Kim, Jiook Cha
NEUROIMAGE-CLINICAL
(2019)