Gut microorganisms as promising targets for the management of type 2 diabetes

Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance

(2015) E. Denou et al.   EMBO Molecular Medicine

Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity

(2015) Injae Hwang et al.   FASEB JOURNAL

Towards a more comprehensive concept for prebiotics

(2015) Laure B. Bindels et al.   Nature Reviews Gastroenterology & Hepatology

Effect of Metformin on Metabolic Improvement and Gut Microbiota

(2014) Heetae Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Gut Dysbiosis and Detection of “Live Gut Bacteria” in Blood of Japanese Patients With Type 2 Diabetes

(2014) Junko Sato et al.   DIABETES CARE

Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

(2014) M L Hartvigsen et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula

(2014) Jia Xu et al.   ISME Journal

Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

(2014) Nicole Reichardt et al.   ISME Journal

Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats

(2014) Raylene A Reimer et al.   JOURNAL OF ENDOCRINOLOGY

Lactobacillus gasseri SBT2055 reduces postprandial and fasting serum non-esterified fatty acid levels in Japanese hypertriacylglycerolemic subjects

(2014) Akihiro Ogawa et al.   Lipids in Health and Disease

FXR is a molecular target for the effects of vertical sleeve gastrectomy

(2014) Karen K. Ryan et al.   NATURE

Mycobiota in gastrointestinal diseases

(2014) Pranab K. Mukherjee et al.   Nature Reviews Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

(2014) S. A. Joyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota and GLP-1

(2014) Amandine Everard et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Saccharomyces boulardii Administration Changes Gut Microbiota and Reduces Hepatic Steatosis, Low-Grade Inflammation, and Fat Mass in Obese and Type 2 Diabetic db/db Mice

(2014) A. Everard et al.   mBio

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

(2014) Amandine Everard et al.   Nature Communications

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Microbiota Modification with Probiotics Induces Hepatic Bile Acid Synthesis via Downregulation of the Fxr-Fgf15 Axis in Mice

(2014) Chiara Degirolamo et al.   Cell Reports

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S

(2014) Vanitha Bala et al.   Frontiers in Physiology

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Molecular mechanism of action of metformin: old or new insights?

(2013) Graham Rena et al.   DIABETOLOGIA

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

Concentrated Arabinoxylan but Not Concentrated β-Glucan in Wheat Bread Has Similar Effects on Postprandial Insulin as Whole-Grain Rye in Porto-arterial Catheterized Pigs

(2013) Kirstine L. Christensen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Concentrated Arabinoxylan in Wheat Bread Has Beneficial Effects as Rye Breads on Glucose and Changes in Gene Expressions in Insulin-Sensitive Tissues of Zucker Diabetic Fatty (ZDF) Rats

(2013) Merete Lindberg Hartvigsen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Nonsense Polymorphism (R392X) in TLR5 Protects from Obesity but Predisposes to Diabetes

(2013) N. M. Al-Daghri et al.   JOURNAL OF IMMUNOLOGY

Age, Dietary Fiber, Breath Methane, and Fecal Short Chain Fatty Acids Are Interrelated in Archaea-Positive Humans

(2013) Judlyn Fernandes et al.   JOURNAL OF NUTRITION

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Oligofructose-enriched inulin improves some inflammatory markers and metabolic endotoxemia in women with type 2 diabetes mellitus: A randomized controlled clinical trial

(2013) Parvin Dehghan et al.   NUTRITION

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR43/FFA2: physiopathological relevance and therapeutic prospects

(2013) Laure B. Bindels et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics

(2013) L. Geurts et al.   Beneficial Microbes

Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota

(2012) Audrey M. Neyrinck et al.   BRITISH JOURNAL OF NUTRITION

G-Protein-Coupled Receptors in Intestinal Chemosensation

(2012) Frank Reimann et al.   Cell Metabolism

Contents of dietary fibre components and their relation to associated bioactive components in whole grain wheat samples from the HEALTHGRAIN diversity screen

(2012) Annica A.M. Andersson et al.   FOOD CHEMISTRY

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

Influence of Cross-Linked Arabinoxylans on the Postprandial Blood Glucose Response in Rats

(2012) Barbara Vogel et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sitagliptin Reduces Hyperglycemia and Increases Satiety Hormone Secretion More Effectively When Used with a Novel Polysaccharide in Obese Zucker Rats

(2012) Raylene A. Reimer et al.   JOURNAL OF NUTRITION

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

The importance of the gut microbiota after bariatric surgery

(2012) Judith Aron-Wisnewsky et al.   Nature Reviews Gastroenterology & Hepatology

Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes

(2012) Philip R. Schauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Digestive and physiologic effects of a wheat bran extract, arabino-xylan-oligosaccharide, in breakfast cereal

(2012) Kevin C. Maki et al.   NUTRITION

Green tea powder and Lactobacillus plantarum affect gut microbiota, lipid metabolism and inflammation in high-fat fed C57BL/6J mice

(2012) Ulrika Axling et al.   Nutrition & Metabolism

Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice

(2012) A M Neyrinck et al.   Nutrition & Diabetes

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

(2011) Janne Prawitt et al.   Current Diabetes Reports

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice

(2011) Audrey M. Neyrinck et al.   PLoS One

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects

(2010) Anne Sofie Andreasen et al.   BRITISH JOURNAL OF NUTRITION

Potential interest of gut microbial changes induced by non-digestible carbohydrates of wheat in the management of obesity and related disorders

(2010) Audrey M Neyrinck et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese

(2010) L. Sun et al.   DIABETES CARE

Alteration of the murine gut microbiota during infection with the parasitic helminth Heligmosomoides polygyrus

(2010) Seth T. Walk et al.   INFLAMMATORY BOWEL DISEASES

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Can dietary fructans lower serum glucose?

(2010) Nana K.A. BONSU et al.   Journal of Diabetes

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

(2009) Patrice D Cani et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Comparison of prebiotic effects of arabinoxylan oligosaccharides and inulin in a simulator of the human intestinal microbial ecosystem

(2009) Charlotte Grootaert et al.   FEMS MICROBIOLOGY ECOLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Human gut microbiota in obesity and after gastric bypass

(2009) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes

(2008) Sandrine P Claus et al.   Molecular Systems Biology

Evaluation of the prebiotic properties of wheat arabinoxylan fractions and induction of hydrolase activity in gut microflora

(2007) Maria Vardakou et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY