Paternal epigenetic programming: evolving metabolic disease risk

Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring

(2016) Mohd Zaki Farah Naquiah et al.   Behavioral and Brain Functions

SpermBase: A Database for Sperm-Borne RNA Contents

(2016) A. Schuster et al.   BIOLOGY OF REPRODUCTION

A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans

(2016) Leah Houri-Ze’evi et al.   CELL

Sperm is epigenetically programmed to regulate gene transcription in embryos

(2016) Marta Teperek et al.   GENOME RESEARCH

High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring

(2016) Thais de Castro Barbosa et al.   Molecular Metabolism

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

(2016) Jennifer E. Cropley et al.   Molecular Metabolism

Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome

(2016) Jackson N. Reilly et al.   Scientific Reports

The MicroRNA Signature of Mouse Spermatozoa Is Substantially Modified During Epididymal Maturation1

(2015) Brett Nixon et al.   BIOLOGY OF REPRODUCTION

I’m Eating for Two: Parental Dietary Effects on Offspring Metabolism

(2015) Oliver J. Rando et al.   CELL

Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome

(2015) Jeremy M. Shea et al.   DEVELOPMENTAL CELL

Developmental Origins of Health and Disease: Integrating Environmental Influences

(2015) Jerrold J. Heindel et al.   ENDOCRINOLOGY

Shifting of undernutrition to overnutrition and its determinants among women of reproductive ages in the 36 low to medium income countries

(2015) Abdullah A. Mamun et al.   Obesity Research & Clinical Practice

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

(2015) Ali B. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

Roll over Weismann: extracellular vesicles in the transgenerational transmission of environmental effects

(2015) Sally A Eaton et al.   Epigenomics

The birth and future health of DOHaD

(2015) M. Hanson   Journal of Developmental Origins of Health and Disease

Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice

(2014) Adam J. Watkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Developmental Programming and Transgenerational Transmission of Obesity

(2014) M.H. Vickers   ANNALS OF NUTRITION AND METABOLISM

Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

(2014) Pankaj Kumar et al.   BMC BIOLOGY

Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity

(2014) Anita Öst et al.   CELL

Programming and Inheritance of Parental DNA Methylomes in Mammals

(2014) Lu Wang et al.   CELL

Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans

(2014) Oded Rechavi et al.   CELL

In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation

(2014) Débora Martínez et al.   Cell Metabolism

Paternal RNA contributions in the Caenorhabditis elegans zygote

(2014) M. Stoeckius et al.   EMBO JOURNAL

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

The rise of regulatory RNA

(2014) Kevin V. Morris et al.   NATURE REVIEWS GENETICS

Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?

(2014) M. A. Hanson et al.   PHYSIOLOGICAL REVIEWS

Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals

(2014) Yanchang Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

(2014) E. J. Radford et al.   SCIENCE

What is a paternal effect?

(2014) Angela J. Crean et al.   TRENDS IN ECOLOGY & EVOLUTION

Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis1

(2013) Clémence Belleannée et al.   BIOLOGY OF REPRODUCTION

Increasing paternal age at childbirth is associated with taller stature and less favourable lipid profiles in their children

(2013) Tim Savage et al.   CLINICAL ENDOCRINOLOGY

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content

(2013) Tod Fullston et al.   FASEB JOURNAL

Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study

(2013) J. S. Tyrrell et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Newborns of obese parents have altered DNA methylation patterns at imprinted genes

(2013) A Soubry et al.   INTERNATIONAL JOURNAL OF OBESITY

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

Parental olfactory experience influences behavior and neural structure in subsequent generations

(2013) Brian G Dias et al.   NATURE NEUROSCIENCE

Structure and function of long noncoding RNAs in epigenetic regulation

(2013) Tim R Mercer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells

(2013) Andrew Sobala et al.   RNA Biology

Paternal age at birth and the risk of obesity in young adulthood: A register-based birth cohort study of norwegian males

(2012) Willy Eriksen et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Daddy Issues: Paternal Effects on Phenotype

(2012) Oliver J. Rando   CELL

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans

(2012) Alyson Ashe et al.   CELL

Developmental origins of non-communicable disease: Implications for research and public health

(2012) Robert Barouki et al.   Environmental Health

piRNA-mediated transgenerational inheritance of an acquired trait

(2012) T. Grentzinger et al.   GENOME RESEARCH

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality

(2012) Bethany A. Buckley et al.   NATURE

Paternal Body Mass Index (BMI) Is Associated with Offspring Intrauterine Growth in a Gender Dependent Manner

(2012) You-Peng Chen et al.   PLoS One

The penetrance of an epigenetic trait in mice is progressively yet reversibly increased by selection and environment

(2012) J. E. Cropley et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Hints of tRNA-Derived Small RNAs Role in RNA Silencing Mechanisms

(2012) Maria Rosa Garcia-Silva et al.   Genes

Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability

(2011)   Epigenetics

Associations between parental and offspring adiposity up to midlife: the contribution of adult lifestyle factors in the 1958 British Birth Cohort Study

(2010) Rachel Cooper et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Maternal High-Fat Diet Promotes Body Length Increases and Insulin Insensitivity in Second-Generation Mice

(2009) Gregory A. Dunn et al.   ENDOCRINOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

(2009) A. P. Feinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Induction and Inheritance of Epigenetic Cardiac Hypertrophy in the Mouse

(2008) Kay D. Wagner et al.   DEVELOPMENTAL CELL

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

(2008) J. C. Jimenez-Chillaron et al.   DIABETES

Birth Weight and Risk of Type 2 Diabetes

(2008)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION