Article
Nutrition & Dietetics
Yujing Zhang, Yuan Xue, Dongdong Zhang, Yaping Liu, Ze Xu, Jiaojiao Gao, Wenjie Li, Xing Li
Summary: The clinical research results on vitamin D supplementation in improving prediabetes are controversial. However, this meta-analysis found that supplementing with vitamin D led to significant improvements in FBG, HbA1c, and FINS among prediabetics. Subgroup analysis showed that certain populations, such as those in Asia and individuals with vitamin D deficiency, may benefit more from long-term vitamin D supplementation in terms of glucose metabolism and insulin resistance.
Review
Nutrition & Dietetics
Agata Pienkowska, Justyna Janicka, Michal Duda, Karena Dzwonnik, Kamila Lip, Aleksandra Medza, Agnieszka Szlagatys-Sidorkiewicz, Michal Brzezinski
Summary: This study aimed to evaluate the potential benefits of vitamin D supplementation in preventing diabetes and found that it does not reduce insulin resistance or the risk of developing type 2 diabetes in prediabetes. Due to the variation in study designs and biases, clear interpretation of the results is not possible, and long-term and well-designed studies are still required.
Article
Endocrinology & Metabolism
Neda Rasouli, Irwin G. Brodsky, Ranee Chatterjee, Sun H. Kim, Richard E. Pratley, Myrlene A. Staten, Anastassios G. Pittas
Summary: Supplementation with vitamin D-3 for 24 months did not improve beta-cell function in people with prediabetes, but showed benefits in those with very low baseline vitamin D levels.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Agriculture, Multidisciplinary
Dongdong Zhang, Xiaoqin Zhong, Cheng Cheng, Zhiwei Su, Yuan Xue, Yaping Liu, Yujing Zhang, Mingming Feng, Ze Xu, Tong Zhao, Luoya Zhang, Haoyue Huang, Wenjie Li, Xing Li
Summary: The potential role of vitamin D in beta-cell function is still debated. A randomized, placebo-controlled trial was conducted to investigate the effect of vitamin D and calcium supplementation on beta-cell function in a Chinese population with prediabetes. The results showed that oral administration of vitamin D and calcium increased insulin secretion. Vitamin D-insufficient individuals had improved glucose tolerance after treatment with vitamin D + calcium. Further research is needed to confirm these findings. Given the low vitamin D content in natural foods, fortification of processed foods with vitamin D is necessary.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Nutrition & Dietetics
Ricardo Usategui-Martin, Daniel-Antonio De Luis-Roman, Jose Maria Fernandez-Gomez, Marta Ruiz-Mambrilla, Jose-Luis Perez-Castrillon
Summary: This study evaluated the impact of polymorphisms in the vitamin D receptor gene on the response to vitamin D supplementation through a systematic review and meta-analysis. The results suggest that the TaqI and FokI polymorphisms may play a role in modulating the response to vitamin D supplementation.
Review
Pharmacology & Pharmacy
Antonio Corsello, Marina Macchi, Veronica D'Oria, Chiara Pigazzi, Ilaria Alberti, Giorgio Treglia, Valentina De Cosmi, Alessandra Mazzocchi, Carlo Agostoni, Gregorio Paolo Milani
Summary: Due to the lipophilic nature of vitamin D, overweight and obese patients have an increased risk of inadequate circulating 25-hydroxy-vitamin D concentrations. Although supplementation strategies of vitamin D for pediatric subjects with excessive body weight have been proposed, the efficacy remains controversial. This systematic review and meta-analysis found that vitamin D supplementation slightly increases 25-hydroxy-vitamin D levels in overweight and obese children and adolescents, but its effects on metabolic and cardiovascular outcomes remain controversial.
PHARMACOLOGICAL RESEARCH
(2023)
Review
Nutrition & Dietetics
Amir Hadi, Omid Asbaghi, Maryam Kazemi, Hossein Khadem Haghighian, Ehsan Ghaedi
Summary: This systematic review and meta-analysis evaluated the effects of pistachio consumption on glucoregulatory status in individuals with a high risk of cardiovascular disease (CVD). The results showed that pistachio consumption, isocaloric with other foods, can decrease fasting blood sugar and insulin concentrations in individuals with a high risk of CVD. However, there was no significant change in insulin resistance levels. It is recommended to conduct well-designed trials with an adequate sample size focusing on diabetic populations due to the limited availability of studies with diabetic cases and relatively small sample sizes.
BRITISH JOURNAL OF NUTRITION
(2023)
Review
Nutrition & Dietetics
Myriam Abboud
Summary: Vitamin D supplementation shows promise in improving sleep quality, but further research is needed regarding its effects on sleep quantity and disorders.
Review
Nutrition & Dietetics
Yi-Yan Pei, Yu Zhang, Xing-Chen Peng, Zhe-Ran Liu, Ping Xu, Fang Fang
Summary: This systematic review and meta-analysis found that vitamin D supplementation was not associated with a lower risk of cardiovascular events or mortality. These findings do not support the routine use of vitamin D supplementation.
Review
Food Science & Technology
Felipe Mendes Delpino, Lilian Munhoz Figueiredo, Bruna Goncalves Cordeiro da Silva, Taiciane Goncalves da Silva, Gicele Costa Mintem, Renata Moraes Bielemann, Denise Petrucci Gigante
Summary: The study found that omega-3 supplementation has significant effects in reducing fasting blood glucose and insulin resistance, but not on glycated hemoglobin levels in diabetes.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Felipe Mendes Delpino, Lilian Munhoz Figueiredo
Summary: The systematic review with meta-analysis showed that resveratrol supplementation has protective effects on diabetes parameters. The analysis revealed significant reduction in insulin resistance and glycated hemoglobin, and a significant impact on fasting blood glucose in individuals with diabetes.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Qinyuan Li, Qi Zhou, Guangli Zhang, Xiaoyin Tian, Yuanyuan Li, Zhili Wang, Yan Zhao, Yaolong Chen, Zhengxiu Luo
Summary: This systematic review and meta-analysis investigated the effects of vitamin D supplementation on children with allergic diseases. The results showed that overall, vitamin D supplementation did not significantly reduce the risk of asthma exacerbations in children. However, it may reduce the risk in children with low baseline serum vitamin D levels. Additionally, vitamin D supplementation was found to reduce the severity of atopic dermatitis and symptoms of allergic rhinitis in children.
Article
Pharmacology & Pharmacy
Evangelia Zaromytidou, Theocharis Koufakis, Georgios Dimakopoulos, Despina Drivakou, Stavroula Konstantinidou, Vasiliki Antonopoulou, Maria Grammatiki, Eleni Manthou, Ioannis Iakovou, Anna Gotzamani-Psarrakou, Kalliopi Kotsa
Summary: This study investigated the effect of vitamin D supplementation on glycemic markers in elderly Greek individuals with prediabetes. The results showed that supplemented participants had significantly increased levels of 25(OH)D and decreased levels of fasting glucose and glycated hemoglobin compared to baseline.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2022)
Review
Endocrinology & Metabolism
Marlene Chakhtoura, Dania S. Bacha, Charbel Gharios, Sara Ajjour, Mariam Assaad, Yara Jabbour, Francesca Kahale, Aya Bassatne, Stephanie Antoun, Elie A. Akl, Roger Bouillon, Paul Lips, Peter R. Ebeling, Ghada El-Hajj Fuleihan
Summary: This umbrella review investigated the quality and discrepancies of systematic reviews/meta-analyses on vitamin D supplementation for fracture risk reduction in adults. The results show that vitamin D combined with calcium can reduce the risk of hip and any fractures, potentially driven by findings from institutionalized individuals. However, there are discrepancies in results due to different trial inclusion, search periods, eligibility criteria, and methodologies used. Individual participant data meta-analyses and subgroup analysis are recommended to further explore determinants for a beneficial response to supplementation.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Virology
Timotius Ivan Hariyanto, Denny Intan, Joshua Edward Hananto, Harapan Harapan, Andree Kurniawan
Summary: Vitamin D supplementation may have beneficial effects on Covid-19 outcomes, reducing ICU admission rate, need for mechanical ventilation, and mortality. Additionally, the associations were found to be influenced by age.
REVIEWS IN MEDICAL VIROLOGY
(2022)