De novosequencing of highly modified therapeutic oligonucleotides by hydrophobic tag sequencing coupled with LC-MS

Clinical and Preclinical Pharmacokinetics and Pharmacodynamics of Mipomersen (Kynamro®): A Second-Generation Antisense Oligonucleotide Inhibitor of Apolipoprotein B

(2015) Richard S. Geary et al.   CLINICAL PHARMACOKINETICS

Bidirectional Direct Sequencing of Noncanonical RNA by Two-Dimensional Analysis of Mass Chromatograms

(2015) Anders Björkbom et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2

(2015) Dominik Oberthür et al.   Nature Communications

Top-Down Interrogation of Chemically Modified Oligonucleotides by Negative Electron Transfer and Collision Induced Dissociation

(2013) Yang Gao et al.   ANALYTICAL CHEMISTRY

De novosequencing of short interfering ribonucleic acids facilitated by use of tandem mass spectrometry with ion mobility spectrometry

(2013) Henry C. Fisher et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Methods for L-ribooligonucleotide sequence determination using LCMS

(2011) John J. Turner et al.   NUCLEIC ACIDS RESEARCH

Hybrid Activation Methods for Elucidating Nucleic Acid Modifications

(2010) Suncerae I. Smith et al.   ANALYTICAL CHEMISTRY

Tandem mass spectrometric de novo sequencing of oligonucleotides using simulated annealing for stochastic optimization

(2010) Herbert Oberacher et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Top-down mass spectrometry for sequencing of larger (up to 61 nt) RNA by CAD and EDD

(2010) Monika Taucher et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Infrared multiphoton dissociation of small-interfering RNA anions and cations

(2010) Myles W. Gardner et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Sequencing of Single and Double Stranded RNA Oligonucleotides by Acid Hydrolysis and MALDI Mass Spectrometry

(2009) Ute Bahr et al.   ANALYTICAL CHEMISTRY

De Novo Sequence Determination of Modified Oligonucleotides

(2009) Julie Farand et al.   ANALYTICAL CHEMISTRY

Ion trap collision-induced dissociation of locked nucleic acids

(2009) Teng-yi Huang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Minimizing base loss and internal fragmentation in collisionally activated dissociation of multiply deprotonated RNA

(2009) Monika Taucher et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Sequence confirmation of chemically modified RNAs using exonuclease digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

(2009) Hong Gao et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Sequence Confirmation of Modified Oligonucleotides Using Chemical Degradation, Electrospray Ionization, Time-of-Flight, and Tandem Mass Spectrometry

(2008) Julie Farand et al.   ANALYTICAL CHEMISTRY