HBV-Derived Synthetic Long Peptide Can Boost CD4+ and CD8+ T-Cell Responses in Chronic HBV Patients Ex Vivo

Hepatitis B Virus–Specific and Global T-Cell Dysfunction in Chronic Hepatitis B

(2016) Jang-June Park et al.   GASTROENTEROLOGY

Restoration of T cell function in chronic hepatitis B patients upon treatment with interferon based combination therapy

(2016) Annikki de Niet et al.   JOURNAL OF HEPATOLOGY

Adaptive immunity in HBV infection

(2016) Antonio Bertoletti et al.   JOURNAL OF HEPATOLOGY

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

(2016) Gijs G. Zom et al.   Oncotarget

The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function

(2016) Evelyn van der Aa et al.   PLoS One

Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation

(2014) Bertram Bengsch et al.   JOURNAL OF HEPATOLOGY

Hepatitis B virus infection

(2014) Christian Trépo et al.   LANCET

Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection

(2014) Jia Liu et al.   PLoS Pathogens

Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates

(2014) G. G. Zom et al.   Cancer Immunology Research

Understanding MHC Class I Presentation of Viral Antigens by Human Dendritic Cells as a Basis for Rational Design of Therapeutic Vaccines

(2014) Nadine van Montfoort et al.   Frontiers in Immunology

Mobilizing monocytes to cross-present circulating viral antigen in chronic infection

(2013) Adam J. Gehring et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase I Trial of Overlapping Long Peptides from a Tumor Self-Antigen and Poly-ICLC Shows Rapid Induction of Integrated Immune Response in Ovarian Cancer Patients

(2012) P. Sabbatini et al.   CLINICAL CANCER RESEARCH

Combined Blockade of Programmed Death-1 and Activation of CD137 Increase Responses of Human Liver T Cells Against HBV, But Not HCV

(2012) Paola Fisicaro et al.   GASTROENTEROLOGY

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

(2012) Carolina Boni et al.   GASTROENTEROLOGY

Restoration of TLR3-Activated Myeloid Dendritic Cell Activity Leads to Improved Natural Killer Cell Function in Chronic Hepatitis B Virus Infection

(2012) Eric T. T. L. Tjwa et al.   JOURNAL OF VIROLOGY

Global epidemiology of hepatitis B virus infection: New estimates of age-specific HBsAg seroprevalence and endemicity

(2012) J.J. Ott et al.   VACCINE

Therapeutic vaccines and immune-based therapies for the treatment of chronic hepatitis B: Perspectives and challenges

(2011) Marie-Louise Michel et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus Lacks Immune Activating Capacity, but Actively Inhibits Plasmacytoid Dendritic Cell Function

(2011) Andrea M. Woltman et al.   PLoS One

CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes

(2010) R. Bos et al.   CANCER RESEARCH

Bystander killing of cancer requires the cooperation of CD4+and CD8+T cells during the effector phase

(2010) Andrea Schietinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines

(2010) Adam J. Gehring et al.   JOURNAL OF HEPATOLOGY

Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B

(2010) Eric T.T.L. Tjwa et al.   JOURNAL OF HEPATOLOGY

Induction of p53-Specific Immunity by a p53 Synthetic Long Peptide Vaccine in Patients Treated for Metastatic Colorectal Cancer

(2009) F. M. Speetjens et al.   CLINICAL CANCER RESEARCH

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

(2009) Paola Fisicaro et al.   GASTROENTEROLOGY

Dendritic cells in chronic viral hepatitis B and C: victims or guardian angels?

(2009) A M Woltman et al.   GUT

CD8 + T Cell Control of Hepatitis B Virus Replication: Direct Comparison between Cytolytic and Noncytolytic Functions

(2009) Sandra Phillips et al.   JOURNAL OF IMMUNOLOGY

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

(2009) Gemma G. Kenter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection

(2008) A. Ross Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

(2008) Abhishek Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Understanding the immunopathogenesis of chronic hepatitis B virus: An Asian prospective

(2008) Anthony Tanoto Tan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Host Ethnicity and Virus Genotype Shape the Hepatitis B Virus-Specific T-Cell Repertoire

(2008) A. T. Tan et al.   JOURNAL OF VIROLOGY

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines

(2008) Q. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA