IL-26 Confers Proinflammatory Properties to Extracellular DNA

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA

(2016) Elizabeth E. Gray et al.   IMMUNITY

DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

(2015) Anetta Härtlova et al.   IMMUNITY

LL37 inhibits the inflammatory endothelial response induced by viral or endogenous DNA

(2015) Monika Merkle et al.   JOURNAL OF AUTOIMMUNITY

Regulation of Pulmonary Graft-versus-Host Disease by IL-26+CD26+CD4 T Lymphocytes

(2015) Kei Ohnuma et al.   JOURNAL OF IMMUNOLOGY

Activation and Regulation of DNA-Driven Immune Responses

(2015) Søren R. Paludan   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

(2015) Stephan Meller et al.   NATURE IMMUNOLOGY

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

Interleukin-26 in Antibacterial Host Defense of Human Lungs. Effects on Neutrophil Mobilization

(2014) Karlhans F. Che et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

(2014) Michael J. White et al.   CELL

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

(2014) Anthony Rongvaux et al.   CELL

IL-26 is overexpressed in chronically HCV-infected patients and enhances TRAIL-mediated cytotoxicity and interferon production by human NK cells

(2014) Charline Miot et al.   GUT

Endogenous Intracellular Cathelicidin Enhances TLR9 Activation in Dendritic Cells and Macrophages

(2014) Yukinobu Nakagawa et al.   JOURNAL OF IMMUNOLOGY

Intrinsic Self-DNA Triggers Inflammatory Disease Dependent on STING

(2014) Jeonghyun Ahn et al.   JOURNAL OF IMMUNOLOGY

The enemy within: endogenous retroelements and autoimmune disease

(2014) Hannah E Volkman et al.   NATURE IMMUNOLOGY

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease

(2014) J. Charles Jennette et al.   Nature Reviews Rheumatology

Activated STING in a Vascular and Pulmonary Syndrome

(2014) Yin Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune sensing of nucleic acids in inflammatory skin diseases

(2014) Olivier Demaria et al.   Seminars in Immunopathology

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

Self Double-Stranded (ds)DNA Induces IL-1  Production from Human Monocytes by Activating NLRP3 Inflammasome in the Presence of Anti-dsDNA Antibodies

(2013) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37

(2012) G. Chamilos et al.   BLOOD

The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles

(2012) P. Lacolley et al.   CARDIOVASCULAR RESEARCH

STING manifests self DNA-dependent inflammatory disease

(2012) J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation

(2012) Murielle Corvaisier et al.   PLOS BIOLOGY

MetaDBSite: a meta approach to improve protein DNA-binding sites prediction

(2011) Jingna Si et al.   BMC Systems Biology

Antimicrobial Peptides Inhibit Polyinosinic-Polycytidylic Acid-Induced Immune Responses

(2011) M. Hasan et al.   JOURNAL OF IMMUNOLOGY

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Structure and function of interleukin-22 and other members of the interleukin-10 family

(2010) Daniela Barretto Barbosa Trivella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interleukin-26: An IL-10-related cytokine produced by Th17 cells

(2010) Raymond P. Donnelly et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis

(2010) E. Nogueira et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

LL-37 Promotes Rapid Sensing of CpG Oligodeoxynucleotides by B Lymphocytes and Plasmacytoid Dendritic Cells

(2009) P. Hurtado et al.   JOURNAL OF IMMUNOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

EULAR recommendations for the management of primary small and medium vessel vasculitis

(2008) C Mukhtyar et al.   ANNALS OF THE RHEUMATIC DISEASES

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

(2008) J Dambacher et al.   GUT

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes

(2008) Kerstin Wolk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE