Activation of Myeloid TLR4 Mediates T Lymphocyte Polarization after Traumatic Brain Injury

Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments

(2016) B. R. Achyut et al.   CANCER BIOLOGY & THERAPY

HMGB1Modulates the Treg/Th17 Ratio in Atherosclerotic Patients

(2016) Jia-wang Ding et al.   Journal of Atherosclerosis and Thrombosis

Crosstalk between bone marrow-derived mesenchymal stem cells and regulatory T cells through a glucocorticoid-induced leucine zipper/developmental endothelial locus-1-dependent mechanism

(2015) Nianlan Yang et al.   FASEB JOURNAL

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses

(2015) Christina E. Arnold et al.   IMMUNOBIOLOGY

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Inflammation After Severe Traumatic Brain Injury

(2015) Raj G. Kumar et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Transfer of Myelin-Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone-Fed Mice

(2015) E. G. Baxi et al.   JOURNAL OF NEUROSCIENCE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia

(2014) Chittappen K. Prajeeth et al.   BRAIN BEHAVIOR AND IMMUNITY

Scale and pattern of atrophy in the chronic stages of moderate-severe TBI

(2014) Robin E. A. Green et al.   Frontiers in Human Neuroscience

T cells in the central nervous system: messengers of destruction or purveyors of protection?

(2014) James T. Walsh et al.   IMMUNOLOGY

Regulatory T Cells in Central Nervous System Injury: A Double-Edged Sword

(2014) James T. Walsh et al.   JOURNAL OF IMMUNOLOGY

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

(2014) Hugo González et al.   Journal of Neuroinflammation

CNS Repair Requires Both Effector and Regulatory T Cells with Distinct Temporal and Spatial Profiles

(2014) C. Raposo et al.   JOURNAL OF NEUROSCIENCE

Blocking Lymphocyte Trafficking with FTY720 Prevents Inflammation-Sensitized Hypoxic–Ischemic Brain Injury in Newborns

(2014) Dianer Yang et al.   JOURNAL OF NEUROSCIENCE

Microstructural abnormality in white matter, regulatory T lymphocytes, and depressive symptoms after stroke

(2014) Fumihiko Yasuno et al.   Psychogeriatrics

Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration

(2014) Richard P Tobin et al.   Acta Neuropathologica Communications

Inflammation and white matter degeneration persist for years after a single traumatic brain injury

(2013) Victoria E. Johnson et al.   BRAIN

Traumatic brain injury induces macrophage subsets in the brain

(2013) Christine L. Hsieh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat

(2013) J. Flygt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reciprocal relation between GADD153 and Del-1 in regulation of salivary gland inflammation in Sjögren syndrome

(2013) Babak Baban et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4

(2013) Melissa D. Laird et al.   GLIA

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

(2013) Guohua Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Plasma high-mobility group box 1 levels and prediction of outcome in patients with traumatic brain injury

(2012) Ke-Yi Wang et al.   CLINICA CHIMICA ACTA

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation

(2012) H. Qin et al.   JOURNAL OF IMMUNOLOGY

Challenging the Role of Adaptive Immunity in Neurotrauma: Rag1−/− Mice Lacking Mature B and T Cells Do Not Show Neuroprotection after Closed Head Injury

(2012) Sebastian Weckbach et al.   JOURNAL OF NEUROTRAUMA

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

(2012) Alok Kumar et al.   NEUROBIOLOGY OF AGING

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis

(2010) Adriana M. C. Mus et al.   ARTHRITIS AND RHEUMATISM

Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model

(2010) Fumie Konoeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species

(2010) Angela Pizzolla et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

(2010) Madhav D. Sharma et al.   IMMUNITY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Inflammatory Effects of Ex Vivo Human Th17 Cells Are Suppressed by Regulatory T Cells

(2010) S. Q. Crome et al.   JOURNAL OF IMMUNOLOGY

Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?

(2010) Melissa D. Laird et al.   JOURNAL OF NEUROCHEMISTRY

High-mobility group box 1 promotes early acute allograft rejection by enhancing IL-6-dependent Th17 alloreactive response

(2010) Lihua Duan et al.   LABORATORY INVESTIGATION

Roles of inflammation response in microglia cell through Toll-like receptors 2/interleukin-23/interleukin-17 pathway in cerebral ischemia/reperfusion injury

(2010) M. Lv et al.   NEUROSCIENCE

Elucidating novel mechanisms of brain injury following subarachnoid hemorrhage: an emerging role for neuroproteomics

(2010) Melanie D. King et al.   Neurosurgical Focus

MHC Class II Molecules Enhance Toll-Like Receptor Mediated Innate Immune Responses

(2010) Remo Frei et al.   PLoS One

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

Invited review: Deterioration of the immune system after trauma: signals and cellular mechanisms

(2008) Stefanie B. Flohé et al.   Innate Immunity