Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells

Polyfunctional, Pathogenic CD161+Th17 Lineage Cells Are Resistant to Regulatory T Cell–Mediated Suppression in the Context of Autoimmunity

(2015) Sharee A. Basdeo et al.   JOURNAL OF IMMUNOLOGY

Demethylation of theRORC2andIL17Ain Human CD4+T Lymphocytes Defines Th17 Origin of Nonclassic Th1 Cells

(2015) Alessio Mazzoni et al.   JOURNAL OF IMMUNOLOGY

Targeting GM-CSF in inflammatory diseases

(2015) Ian P. Wicks et al.   Nature Reviews Rheumatology

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids

(2014) Radha Ramesh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TNF-α blockade induces IL-10 expression in human CD4+ T cells

(2014) Hayley G. Evans et al.   Nature Communications

Main features of human T helper 17 cells

(2013) Francesco Annunziato et al.   Annals of the New York Academy of Sciences

IL-17/Th17 mediated synovial inflammation is IL-22 independent

(2013) Jan Piet van Hamburg et al.   ANNALS OF THE RHEUMATIC DISEASES

Reasons for rarity of Th17 cells in inflammatory sites of human disorders

(2013) Francesco Annunziato et al.   SEMINARS IN IMMUNOLOGY

Effect of IL-17A blockade with secukinumab in autoimmune diseases

(2012) Dhavalkumar D Patel et al.   ANNALS OF THE RHEUMATIC DISEASES

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

(2012) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Th17 subsets

(2012) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

CD4+CD161+ T Lymphocytes Infiltrate Crohn’s Disease-Associated Perianal Fistulas and Are Reduced by Anti-TNF-a Local Therapy

(2012) Laura Maggi et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Defining the human T helper 17 cell phenotype

(2012) Francesco Annunziato et al.   TRENDS IN IMMUNOLOGY

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

(2011) Lorenzo Cosmi et al.   ARTHRITIS AND RHEUMATISM

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature

(2011) Pawel Muranski et al.   IMMUNITY

Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression

(2011) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Human TH17 Cells Are Long-Lived Effector Memory Cells

(2011) I. Kryczek et al.   Science Translational Medicine

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Linking Power Doppler Ultrasound to the Presence of Th17 Cells in the Rheumatoid Arthritis Joint

(2010) Nicola J. Gullick et al.   PLoS One

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

Translational Mini-Review Series on Th17 Cells: Function and regulation of human T helper 17 cells in health and disease

(2009) S. Q. Crome et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation

(2008) F. Annunziato et al.   INTERNATIONAL IMMUNOLOGY

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TH-17 cells in rheumatoid arthritis

(2008) Shiva Shahrara et al.   ARTHRITIS RESEARCH & THERAPY