Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

(2015) Denise N. Bronner et al.   IMMUNITY

A novel N-acetyl-glucosamine lectin of Lonchocarpus araripensis attenuates acute cellular inflammation in mice

(2015) Alana F. Pires et al.   INFLAMMATION RESEARCH

Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury

(2015) M Deutsch et al.   Cell Death & Disease

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients

(2013) Lucas Vicuña et al.   BIOLOGICAL RESEARCH

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

(2013) Yiqing Yan et al.   IMMUNITY

Integrin inactivators: balancing cellular functions in vitro and in vivo

(2013) Daniel Bouvard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Jacalin Bound Plasma O-Glycoproteome and Reduced Sialylation of Alpha 2-HS Glycoprotein (A2HSG) in Rheumatoid Arthritis Patients

(2012) Ashish Saroha et al.   PLoS One

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mannose binding lectin: a biomarker of systemic lupus erythematosus disease activity

(2012) Aditya K Panda et al.   ARTHRITIS RESEARCH & THERAPY

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

(2012) P Menu et al.   Cell Death & Disease

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Differential Expression of NLRP3 among Hematopoietic Cells

(2011) G. Guarda et al.   JOURNAL OF IMMUNOLOGY

Antinociceptive and anti-inflammatory activities of lectin from the marine green alga Caulerpa cupressoides

(2010) Edfranck Sousa Oliveira Vanderlei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dietary garlic (Allium sativum) lectins, ASA I and ASA II, are highly stable and immunogenic

(2010) Fatima Clement et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury

(2009) Kenshi Yamasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

Effects of wheat germ agglutinin on human gastrointestinal epithelium: Insights from an experimental model of immune/epithelial cell interaction

(2009) Chiara Dalla Pellegrina et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Superoxide produced by Kupffer cells is an essential effector in concanavalin A-induced hepatitis in mice

(2008) Hiroyuki Nakashima et al.   HEPATOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY