Genetic engineering in nonhuman primates for human disease modeling

TALEN-based generation of a cynomolgus monkey disease model for human microcephaly

(2016) Qiong Ke et al.   CELL RESEARCH

Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing

(2016) Kenya Sato et al.   Cell Stem Cell

Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2

(2016) Zhen Liu et al.   NATURE

Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body

(2016) Yasunari Seita et al.   Scientific Reports

Generation of macaques with sperm derived from juvenile monkey testicular xenografts

(2015) Zhen Liu et al.   CELL RESEARCH

Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis

(2015) Thorsten Boroviak et al.   DEVELOPMENTAL CELL

Germline transmission in transgenic Huntington's disease monkeys

(2015) Sean Moran et al.   THERIOGENOLOGY

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

TALEN-Mediated Gene Mutagenesis in Rhesus and Cynomolgus Monkeys

(2014) Hailiang Liu et al.   Cell Stem Cell

Generation of a monkey with MECP2 mutations by TALEN-based gene targeting

(2014) Zhen Liu et al.   Neuroscience Bulletin

Efficient TALEN construction and evaluation methods for human cell and animal applications

(2013) Tetsushi Sakuma et al.   GENES TO CELLS

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

(2013) Y. H. Sung et al.   GENOME RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity

(2013) Tetsushi Sakuma et al.   Scientific Reports

Accessing naïve human pluripotency

(2012) Alejandro De Los Angeles et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

TALENs: a widely applicable technology for targeted genome editing

(2012) J. Keith Joung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome Engineering With Zinc-Finger Nucleases

(2011) Dana Carroll   GENETICS

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) T. Cermak et al.   NUCLEIC ACIDS RESEARCH

Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28

(2010) Ikuo Tomioka et al.   GENES TO CELLS

Gene Targeting and Subsequent Site-Specific Transgenesis at the β-actin (ACTB) Locus in Common Marmoset Embryonic Stem Cells

(2010) Seiji Shiozawa et al.   STEM CELLS AND DEVELOPMENT

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Generation of transgenic non-human primates with germline transmission

(2009) Erika Sasaki et al.   NATURE

Towards a transgenic model of Huntington’s disease in a non-human primate

(2008) Shang-Hsun Yang et al.   NATURE