Distribution of FcRn Across Species and Tissues

Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS

(2016) Yao-Yun Fan et al.   ANALYTICAL CHEMISTRY

Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

(2016) Lindsay B. Avery et al.   mAbs

Tissue expression profile of human neonatal Fc receptor (FcRn) in Tg32 transgenic mice

(2016) Yao-Yun Fan et al.   mAbs

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity

(2015) Yasmina Noubia Abdiche et al.   mAbs

FcRn Expression on Placenta and Fetal Jejunum during Early, Mid-, and Late Gestation in Minipigs

(2015) Björn Jacobsen et al.   TOXICOLOGIC PATHOLOGY

A Comparison of the Histological Structure of the Placenta in Experimental Animals

(2014) Satoshi Furukawa et al.   Journal of Toxicologic Pathology

The Role of FcRn in Antigen Presentation

(2014) Kristi Baker et al.   Frontiers in Immunology

Neonatal Fc Receptor Expression in Dendritic Cells Mediates Protective Immunity against Colorectal Cancer

(2013) Kristi Baker et al.   IMMUNITY

Correlations between pharmacokinetics of IgG antibodies in primates vs. FcRn-transgenic mice reveal a rodent model with predictive capabilities

(2013) Susan H. Tam et al.   mAbs

Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies

(2013) Gabriele Proetzel et al.   METHODS

Human and Non-Human Primate Intestinal FcRn Expression and Immunoglobulin G Transcytosis

(2013) Pamela J. Hornby et al.   PHARMACEUTICAL RESEARCH

Abundant Intracellular IgG in Enterocytes and Endoderm Lacking FcRn

(2013) Sudhasri Mohanty et al.   PLoS One

FcRn Overexpression in Transgenic Mice Results in Augmented APC Activity and Robust Immune Response with Increased Diversity of Induced Antibodies

(2012) Attila Végh et al.   PLoS One

Neonatal Fc receptor and IgG-based therapeutics

(2011) Timothy T. Kuo et al.   mAbs

Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates

(2009) Y. A. Yeung et al.   JOURNAL OF IMMUNOLOGY

FcRn in the Yolk Sac Endoderm of Mouse Is Required for IgG Transport to Fetus

(2009) J. Kim et al.   JOURNAL OF IMMUNOLOGY

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

(2009) Héctor Pérez Montoyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular engineering and design of therapeutic antibodies

(2008) Leonard G Presta   CURRENT OPINION IN IMMUNOLOGY